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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0117
         (696 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Y10498-1|CAA71523.3|  266|Homo sapiens thymidine kinase 2 protein.     82   2e-15
U80628-1|AAC51168.1|  224|Homo sapiens thymidine kinase 2 isofor...    82   2e-15
U77088-1|AAC51167.1|  234|Homo sapiens thymidine kinase 2 protein.     82   2e-15
BC134344-1|AAI34345.1|  229|Homo sapiens TK2 protein protein.          82   2e-15
AF521891-1|AAN73847.1|  307|Homo sapiens thymidine kinase protein.     82   2e-15
BC142970-1|AAI42971.1|  216|Homo sapiens TK2 protein protein.          79   2e-14
M60527-1|AAA35752.1|  260|Homo sapiens deoxycytidine kinase prot...    56   9e-08
CR541876-1|CAG46674.1|  260|Homo sapiens DCK protein.                  56   9e-08
CR536527-1|CAG38764.1|  260|Homo sapiens DCK protein.                  56   9e-08
BT019942-1|AAV38745.1|  260|Homo sapiens deoxycytidine kinase pr...    56   9e-08
BT019941-1|AAV38744.1|  260|Homo sapiens deoxycytidine kinase pr...    56   9e-08
BC114617-1|AAI14618.1|  260|Homo sapiens deoxycytidine kinase pr...    56   9e-08
BC103764-1|AAI03765.1|  260|Homo sapiens deoxycytidine kinase pr...    56   9e-08
X97386-1|CAA66054.1|  260|Homo sapiens deoxyguanosine kinase pro...    53   1e-06
U41668-1|AAC50624.1|  277|Homo sapiens deoxyguanosine kinase pro...    52   1e-06
BC015757-1|AAH15757.1|  277|Homo sapiens deoxyguanosine kinase p...    52   1e-06
AC073046-3|AAX88910.1|  277|Homo sapiens unknown protein.              52   1e-06
AK131259-1|BAD18437.1|  512|Homo sapiens   protein.                    48   3e-05

>Y10498-1|CAA71523.3|  266|Homo sapiens thymidine kinase 2 protein.
          Length = 266

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 32/58 (55%), Positives = 43/58 (74%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+P   YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 164 WFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 221



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 108 TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 161



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 83  VSKWRNVRGHNPLGLMYHDASRWG 106


>U80628-1|AAC51168.1|  224|Homo sapiens thymidine kinase 2 isoform B
           protein.
          Length = 224

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 32/58 (55%), Positives = 43/58 (74%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+P   YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 123 WFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 180



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 67  TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 120



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 42  VSKWRNVRGHNPLGLMYHDASRWG 65


>U77088-1|AAC51167.1|  234|Homo sapiens thymidine kinase 2 protein.
          Length = 234

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 32/58 (55%), Positives = 43/58 (74%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+P   YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 133 WFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 190



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 77  TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 130



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 52  VSKWRNVRGHNPLGLMYHDASRWG 75


>BC134344-1|AAI34345.1|  229|Homo sapiens TK2 protein protein.
          Length = 229

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 32/58 (55%), Positives = 43/58 (74%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+P   YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 128 WFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 185



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 72  TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 125



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 47  VSKWRNVRGHNPLGLMYHDASRWG 70


>AF521891-1|AAN73847.1|  307|Homo sapiens thymidine kinase protein.
          Length = 307

 Score = 82.2 bits (194), Expect = 2e-15
 Identities = 32/58 (55%), Positives = 43/58 (74%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+P   YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 206 WFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 263



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 150 TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 203



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 125 VSKWRNVRGHNPLGLMYHDASRWG 148


>BC142970-1|AAI42971.1|  216|Homo sapiens TK2 protein protein.
          Length = 216

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 31/58 (53%), Positives = 42/58 (72%)
 Frame = +1

Query: 256 WFXFIQHNIPIDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLI 429
           WF +I  N+ +  DLIVYL+T+    YQR+KKR R EE+ +PL Y+E +H LHE+WLI
Sbjct: 115 WFDWILRNMDVSVDLIVYLRTNHETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLI 172



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 28/54 (51%), Positives = 37/54 (68%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPTPVKLMERSLFSARYCFVEHMMRNNTLHPAQFAVL 250
           T Q+YV LTMLD H RP  + V+LMERS+ SARY FVE++ R+  +    + VL
Sbjct: 59  TLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL 112



 Score = 32.3 bits (70), Expect = 1.7
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +3

Query: 12  VEMWRDLKGCNLLELMYKDPEKWG 83
           V  WR+++G N L LMY D  +WG
Sbjct: 34  VSKWRNVRGHNPLGLMYHDASRWG 57


>M60527-1|AAA35752.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>CR541876-1|CAG46674.1|  260|Homo sapiens DCK protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>CR536527-1|CAG38764.1|  260|Homo sapiens DCK protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>BT019942-1|AAV38745.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>BT019941-1|AAV38744.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>BC114617-1|AAI14618.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>BC103764-1|AAI03765.1|  260|Homo sapiens deoxycytidine kinase
           protein.
          Length = 260

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 23/50 (46%), Positives = 34/50 (68%)
 Frame = +1

Query: 286 IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           ++ D I+YL+ +P     RI  R R+EEQ +PL Y+E+LH  HE WL++R
Sbjct: 170 LELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHR 219


>X97386-1|CAA66054.1|  260|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 260

 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 20/44 (45%), Positives = 33/44 (75%)
 Frame = +1

Query: 304 VYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           +YL+ SP +  +R+ +RAR EE+ + L+Y+E+LH  HE WLI++
Sbjct: 173 IYLQASPQVCLKRLYQRAREEEEGIELAYLEQLHGQHEAWLIHK 216



 Score = 35.5 bits (78), Expect = 0.18
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 7/60 (11%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPT-------PVKLMERSLFSARYCFVEHMMRNNTLHPAQFAV 247
           TFQ++  L+ L +   P P        PV++ ERS++S RY F +++  N++L   ++ +
Sbjct: 92  TFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENDSLSDIEWHI 151


>U41668-1|AAC50624.1|  277|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 277

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 20/44 (45%), Positives = 33/44 (75%)
 Frame = +1

Query: 304 VYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           +YL+ SP +  +R+ +RAR EE+ + L+Y+E+LH  HE WLI++
Sbjct: 190 IYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHK 233



 Score = 35.1 bits (77), Expect = 0.24
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 7/60 (11%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPT-------PVKLMERSLFSARYCFVEHMMRNNTLHPAQFAV 247
           TFQ++  L+ L +   P P        PV++ ERS++S RY F +++  N +L   ++ +
Sbjct: 109 TFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHI 168


>BC015757-1|AAH15757.1|  277|Homo sapiens deoxyguanosine kinase
           protein.
          Length = 277

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 20/44 (45%), Positives = 33/44 (75%)
 Frame = +1

Query: 304 VYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           +YL+ SP +  +R+ +RAR EE+ + L+Y+E+LH  HE WLI++
Sbjct: 190 IYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHK 233



 Score = 35.1 bits (77), Expect = 0.24
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 7/60 (11%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPT-------PVKLMERSLFSARYCFVEHMMRNNTLHPAQFAV 247
           TFQ++  L+ L +   P P        PV++ ERS++S RY F +++  N +L   ++ +
Sbjct: 109 TFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHI 168


>AC073046-3|AAX88910.1|  277|Homo sapiens unknown protein.
          Length = 277

 Score = 52.4 bits (120), Expect = 1e-06
 Identities = 20/44 (45%), Positives = 33/44 (75%)
 Frame = +1

Query: 304 VYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWLINR 435
           +YL+ SP +  +R+ +RAR EE+ + L+Y+E+LH  HE WLI++
Sbjct: 190 IYLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHK 233



 Score = 35.1 bits (77), Expect = 0.24
 Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 7/60 (11%)
 Frame = +2

Query: 89  TFQSYVSLTMLDMHRRPAPT-------PVKLMERSLFSARYCFVEHMMRNNTLHPAQFAV 247
           TFQ++  L+ L +   P P        PV++ ERS++S RY F +++  N +L   ++ +
Sbjct: 109 TFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHI 168


>AK131259-1|BAD18437.1|  512|Homo sapiens   protein.
          Length = 512

 Score = 48.0 bits (109), Expect = 3e-05
 Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
 Frame = +1

Query: 256 WFXFIQHNIP-IDADLIVYLKTSPSIVYQRIKKRARSEEQCVPLSYIEELHRLHEDWL 426
           WF  +  ++P +  D  +YL+ SP   ++R+  R R+EE  V L Y+ +LH  HE WL
Sbjct: 319 WFDPVVSSLPGLIPDGFIYLRASPDTCHKRMMLRKRTEEGGVSLDYLCDLHEKHESWL 376


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,054,648
Number of Sequences: 237096
Number of extensions: 1937566
Number of successful extensions: 5143
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4912
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5139
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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