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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0106
         (699 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

EF506887-1|ABO43040.1|  527|Homo sapiens polymerase (DNA directe...   108   2e-23
BC126220-1|AAI26221.1|  527|Homo sapiens polymerase (DNA directe...   108   2e-23
BC126218-1|AAI26219.1|  527|Homo sapiens polymerase (DNA directe...   108   2e-23
BC112962-1|AAI12963.1|  502|Homo sapiens POLE2 protein protein.       108   2e-23
AF387034-1|AAK72254.1|  527|Homo sapiens DNA polymerase epsilon ...   108   2e-23
AF036899-1|AAC39610.1|  527|Homo sapiens DNA polymerase epsilon ...   108   2e-23
AF025840-1|AAC51920.1|  526|Homo sapiens DNA polymerase epsilon ...   108   2e-23

>EF506887-1|ABO43040.1|  527|Homo sapiens polymerase (DNA directed),
           epsilon 2 (p59 subunit) protein.
          Length = 527

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>BC126220-1|AAI26221.1|  527|Homo sapiens polymerase (DNA directed),
           epsilon 2 (p59 subunit) protein.
          Length = 527

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>BC126218-1|AAI26219.1|  527|Homo sapiens polymerase (DNA directed),
           epsilon 2 (p59 subunit) protein.
          Length = 527

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>BC112962-1|AAI12963.1|  502|Homo sapiens POLE2 protein protein.
          Length = 502

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>AF387034-1|AAK72254.1|  527|Homo sapiens DNA polymerase epsilon
           subunit B protein.
          Length = 527

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>AF036899-1|AAC39610.1|  527|Homo sapiens DNA polymerase epsilon
           small subunit protein.
          Length = 527

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


>AF025840-1|AAC51920.1|  526|Homo sapiens DNA polymerase epsilon
           subunit B protein.
          Length = 526

 Score =  108 bits (259), Expect = 2e-23
 Identities = 63/156 (40%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
 Frame = +1

Query: 250 IRKEHLEIAFKECSASGLEETETVLNVIDAFNIPKLSYDNERNKFVKSVHKN----NLYP 417
           I +  +E A +ECS S  E  E V N+I AF+IP+  Y++ER KF+  +  N    NL+ 
Sbjct: 62  IERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFG 121

Query: 418 EPKWKAQFLIDRYEIIWQRTVRNKLFAQEACLHWAEEK--YFQLRKIEALLSSSSRIDDV 591
            P+ KA+   +RY I+ QRT R++LF         +E    FQL+ IE LL S+++I D 
Sbjct: 122 TPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDA 181

Query: 592 IVLGLLIQLTEGNITWKIQLGSVVLDMSPTRYHSRL 699
           IVLG++ QL EG    +   G+V LD+S  ++HS L
Sbjct: 182 IVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGL 217


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,024,717
Number of Sequences: 237096
Number of extensions: 2023231
Number of successful extensions: 4051
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3912
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4030
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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