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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= pg--0064.Seq
         (630 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC001627-1|AAH01627.1|  578|Homo sapiens 2-hydroxyacyl-CoA lyase...   147   2e-35
AJ131753-1|CAB60200.1|  578|Homo sapiens 2-hydroxyphytanoyl-CoA ...   146   4e-35
AK125241-1|BAC86096.1|  569|Homo sapiens protein ( Homo sapiens ...   102   1e-21
U61263-1|AAC50934.1|  632|Homo sapiens acetolactate synthase hom...    54   4e-07
BC011761-1|AAH11761.1|  632|Homo sapiens ilvB (bacterial acetola...    54   4e-07
BC011722-1|AAH11722.1|  632|Homo sapiens ilvB (bacterial acetola...    54   4e-07
AC004794-3|AAC18916.1|  393|Homo sapiens Acetolactate synthase p...    54   4e-07
AC003956-1|AAB94632.1|  632|Homo sapiens acetolactate synthase p...    54   4e-07
BC110508-1|AAI10509.1| 1248|Homo sapiens DKFZP586P0123 protein p...    31   4.5  
AK125894-1|BAC86334.1| 1224|Homo sapiens rp86).  protein.              31   4.5  
AB231764-1|BAE17137.1| 1963|Homo sapiens hypothetical protein pr...    31   4.5  

>BC001627-1|AAH01627.1|  578|Homo sapiens 2-hydroxyacyl-CoA lyase 1
           protein.
          Length = 578

 Score =  147 bits (357), Expect = 2e-35
 Identities = 81/197 (41%), Positives = 113/197 (57%)
 Frame = +3

Query: 3   RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
           R+NW+LHFG PPRY PDVK IQV+I    +    +  ++  L +         + + K  
Sbjct: 282 RLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT-LLGNIHAVTKQLLEELDKTP 340

Query: 183 LIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGAN 362
                + +       + KS     +  AS  ++P+NYYTVF  VQ+ +P+D  +VSEGAN
Sbjct: 341 WQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGAN 400

Query: 363 TMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVLKETLLLAS 542
           TMDIGR +L N  PRHRLDAGTFGTMGVG GFAIAAA+  +D +PG+ +  ++       
Sbjct: 401 TMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVE-----GD 455

Query: 543 QAWX*RHVPVQVTCNYN 593
            A+    + V+  C YN
Sbjct: 456 SAFGFSGMEVETICRYN 472



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/66 (24%), Positives = 35/66 (53%)
 Frame = +1

Query: 46  RPTLKLFRSKYLLQEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLK 225
           +P +K  +     +E  N+ K  + +  +I   T+ L++ L +  +   P++  WW+ L+
Sbjct: 296 QPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESK-WWKTLR 354

Query: 226 QKQKAN 243
           +K K+N
Sbjct: 355 EKMKSN 360


>AJ131753-1|CAB60200.1|  578|Homo sapiens 2-hydroxyphytanoyl-CoA
           lyase protein.
          Length = 578

 Score =  146 bits (355), Expect = 4e-35
 Identities = 81/197 (41%), Positives = 112/197 (56%)
 Frame = +3

Query: 3   RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
           R+NW+LHFG PPRY PDVK IQV+I    +    +  ++  L +         + + K  
Sbjct: 282 RLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVT-LLGNIHAVTKQLLEELDKTP 340

Query: 183 LIATSKQQLVAGTETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGAN 362
                + +       + KS     +  AS  ++P+NYYTVF  VQ+ +P+D  +VSEGAN
Sbjct: 341 WQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGAN 400

Query: 363 TMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRVFVLKETLLLAS 542
           TMDIGR +L N  PRHRLDAGTFGTMGVG GFAIAAA+  +D +PG  +  ++       
Sbjct: 401 TMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGHWIICVE-----GD 455

Query: 543 QAWX*RHVPVQVTCNYN 593
            A+    + V+  C YN
Sbjct: 456 SAFGFSGMEVETICRYN 472



 Score = 36.7 bits (81), Expect = 0.068
 Identities = 16/66 (24%), Positives = 35/66 (53%)
 Frame = +1

Query: 46  RPTLKLFRSKYLLQEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLK 225
           +P +K  +     +E  N+ K  + +  +I   T+ L++ L +  +   P++  WW+ L+
Sbjct: 296 QPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTPWQYPPESK-WWKTLR 354

Query: 226 QKQKAN 243
           +K K+N
Sbjct: 355 EKMKSN 360


>AK125241-1|BAC86096.1|  569|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43251 fis, clone HEART2006131, weakly  similar
           to Mus musculus 2-hydroxyphytanoyl-CoA lyase
           (Hpcl-pending). ).
          Length = 569

 Score =  102 bits (244), Expect = 1e-21
 Identities = 62/173 (35%), Positives = 96/173 (55%), Gaps = 4/173 (2%)
 Frame = +3

Query: 3   RMNWMLHFGQPPRYAPDVKIIQVEISPARISQQQEIRISSTLRH*TFYRSSCKKVVRKEV 182
           R+NW+LH+G  PR++  V+ IQ++I+P  +   ++  +   L       S   + +  + 
Sbjct: 277 RLNWILHYGHSPRWSNKVRFIQIDIAPEELGNNRQDTLP-LLGDIQLVVSQITQALTGK- 334

Query: 183 LIATSKQQLVAGTETETKS---KHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSII-VS 350
            ++      V+G   + K    K +   ++ S +A+ LNY T F  ++  +P++ I+ VS
Sbjct: 335 -LSNINPDYVSGLVNKVKQNVEKTKTAGSKGSDSAI-LNYSTAFTVIKSLLPENDIVYVS 392

Query: 351 EGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKRV 509
           EGANTMDIGR     + PRHRLDAGT  TMGVG G+AI A  +   Y   KRV
Sbjct: 393 EGANTMDIGRSYFDVHEPRHRLDAGTGATMGVGMGYAIGAQSY---YGDAKRV 442


>U61263-1|AAC50934.1|  632|Homo sapiens acetolactate synthase
           homolog protein.
          Length = 632

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/88 (34%), Positives = 46/88 (52%)
 Frame = +3

Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
           E + + +    E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
           P   LD G FGT+GVG GFA+ A + CR
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR 510


>BC011761-1|AAH11761.1|  632|Homo sapiens ilvB (bacterial
           acetolactate synthase)-like protein.
          Length = 632

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/88 (34%), Positives = 46/88 (52%)
 Frame = +3

Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
           E + + +    E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
           P   LD G FGT+GVG GFA+ A + CR
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR 510


>BC011722-1|AAH11722.1|  632|Homo sapiens ilvB (bacterial
           acetolactate synthase)-like protein.
          Length = 632

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/88 (34%), Positives = 46/88 (52%)
 Frame = +3

Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
           E + + +    E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
           P   LD G FGT+GVG GFA+ A + CR
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR 510


>AC004794-3|AAC18916.1|  393|Homo sapiens Acetolactate synthase
           protein.
          Length = 393

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/88 (34%), Positives = 46/88 (52%)
 Frame = +3

Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
           E + + +    E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 185 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 244

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
           P   LD G FGT+GVG GFA+ A + CR
Sbjct: 245 PLRWLDPGAFGTLGVGAGFALGAKL-CR 271


>AC003956-1|AAB94632.1|  632|Homo sapiens acetolactate synthase
           protein.
          Length = 632

 Score = 54.0 bits (124), Expect = 4e-07
 Identities = 30/88 (34%), Positives = 46/88 (52%)
 Frame = +3

Query: 222 ETETKSKHRICEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 401
           E + + +    E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCR 485
           P   LD G FGT+GVG GFA+ A + CR
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR 510


>BC110508-1|AAI10509.1| 1248|Homo sapiens DKFZP586P0123 protein
           protein.
          Length = 1248

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
 Frame = +3

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKR-VFVLKETLLLA 539
           P  RL    F   G+ PG  +   +WCR Y P  R   V K TL L+
Sbjct: 373 PVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLS 419


>AK125894-1|BAC86334.1| 1224|Homo sapiens rp86).  protein.
          Length = 1224

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
 Frame = +3

Query: 402 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKR-VFVLKETLLLA 539
           P  RL    F   G+ PG  +   +WCR Y P  R   V K TL L+
Sbjct: 349 PVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLS 395


>AB231764-1|BAE17137.1| 1963|Homo sapiens hypothetical protein
            protein.
          Length = 1963

 Score = 30.7 bits (66), Expect = 4.5
 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
 Frame = +3

Query: 402  PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGKR-VFVLKETLLLA 539
            P  RL    F   G+ PG  +   +WCR Y P  R   V K TL L+
Sbjct: 1088 PVQRLLLSAFSAQGLVPGGGVQFEIWCRYYYPNVRDQKVAKGTLPLS 1134


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,888,512
Number of Sequences: 237096
Number of extensions: 2022372
Number of successful extensions: 8812
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8584
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8805
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6860268620
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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