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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fbpv0091
         (776 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w...    81   6e-15
AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w...    81   6e-15
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte...    81   6e-15
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ...    81   6e-15
AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w...    77   7e-14
AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w...    77   7e-14
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.             77   7e-14
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein...    72   3e-12
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.      71   4e-12
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w...    71   4e-12
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.             71   4e-12
BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase w...    66   1e-10
BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase w...    66   1e-10
AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.        66   1e-10
AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and ...    63   9e-10
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida...    62   2e-09
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w...    62   2e-09
DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative s...    61   5e-09
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte...    61   5e-09
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.     61   5e-09
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.     61   5e-09
AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.              56   2e-07
AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.    55   2e-07
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.    55   2e-07
AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease AD...    55   2e-07
BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase w...    55   3e-07
BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase w...    55   3e-07
AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.        55   3e-07
AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase w...    55   3e-07
AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease disinte...    55   3e-07
AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.        55   3e-07
AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.     55   3e-07
BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase w...    54   6e-07
AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with th...    54   6e-07
AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease ...    54   6e-07
AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with ...    54   6e-07
AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.        54   6e-07
AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.     54   6e-07
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w...    53   1e-06
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.    53   1e-06
AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease AD...    53   1e-06
AB209497-1|BAD92734.1|  527|Homo sapiens a disintegrin and metal...    53   1e-06
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.     52   2e-06
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ...    52   2e-06
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w...    52   3e-06
AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens ...    52   3e-06
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte...    52   3e-06
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.            52   3e-06
AP001698-1|BAA95504.1|  412|Homo sapiens disintegrin-like and me...    50   9e-06
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w...    50   1e-05
BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.      50   1e-05
BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.      50   1e-05
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ...    50   1e-05
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot...    50   1e-05
AF175283-1|AAF25806.1|  246|Homo sapiens zinc metalloendopeptida...    50   1e-05
AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.        50   1e-05
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.     50   1e-05
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.    48   5e-05
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.    48   5e-05
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ...    48   5e-05
AK128469-1|BAC87455.1|  327|Homo sapiens protein ( Homo sapiens ...    46   1e-04
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w...    45   3e-04
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c...    45   3e-04
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ...    45   3e-04
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ...    45   3e-04
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w...    45   3e-04
AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ...    45   3e-04
AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ...    45   3e-04
AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ...    45   3e-04
AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein, trun...    45   3e-04
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari...    45   3e-04
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.    45   3e-04
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.             45   3e-04
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c...    45   3e-04
AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and me...    45   4e-04
AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.      44   6e-04
U41766-1|AAC50403.1|  819|Homo sapiens metalloprotease/disintegr...    41   0.006
D14665-1|BAA03499.2|  703|Homo sapiens KIAA0021 protein protein.       41   0.006
BC126406-1|AAI26407.1|  712|Homo sapiens ADAM9 protein protein.        41   0.006
AF495383-1|AAM49575.1|  655|Homo sapiens disintegrin/metalloprot...    41   0.006
DQ995342-1|ABI97387.1|  813|Homo sapiens ADAM metallopeptidase d...    40   0.008
AY358314-1|AAQ88680.1|  813|Homo sapiens Adam33 protein.               40   0.008
AL356755-2|CAI23465.1|  813|Homo sapiens ADAM metallopeptidase d...    40   0.008
AL356755-1|CAM28348.1|  812|Homo sapiens ADAM metallopeptidase d...    40   0.008
AL109804-2|CAI18840.1|  813|Homo sapiens ADAM metallopeptidase d...    40   0.008
AL109804-1|CAM26955.1|  812|Homo sapiens ADAM metallopeptidase d...    40   0.008
AF466288-1|AAM80483.1|  812|Homo sapiens a disintegrin and metal...    40   0.008
AF466287-1|AAM80482.1|  812|Homo sapiens a disintegrin and metal...    40   0.008
AB055891-1|BAB83092.1|  813|Homo sapiens metalloprotease disinte...    40   0.008
U46005-1|AAC51112.1|  814|Homo sapiens MDC15 protein.                  40   0.013
U41767-1|AAC50404.1|  814|Homo sapiens metargidin precursor prot...    40   0.013
BT009764-1|AAP88766.1|  814|Homo sapiens a disintegrin and metal...    40   0.013
BC014566-1|AAH14566.1|  814|Homo sapiens ADAM metallopeptidase d...    40   0.013
AY576417-1|AAS73000.1|  797|Homo sapiens ADAM15 isoform 8 protein.     40   0.013
AY560601-1|AAS72999.1|  822|Homo sapiens ADAM15 isoform 7b protein.    40   0.013
AY560600-1|AAS72998.1|  821|Homo sapiens ADAM15 isoform 7a protein.    40   0.013
AY560599-1|AAS72997.1|  863|Homo sapiens ADAM15 isoform 6b protein.    40   0.013
AY560598-1|AAS72996.1|  862|Homo sapiens ADAM15 isoform 6a protein.    40   0.013
AY560597-1|AAS72995.1|  838|Homo sapiens ADAM15 isoform 5 protein.     40   0.013
AY560596-1|AAS72994.1|  839|Homo sapiens ADAM15 isoform 4a protein.    40   0.013
AY560595-1|AAS72993.1|  796|Homo sapiens ADAM15 isoform 3a protein.    40   0.013
AY560594-1|AAS72992.1|  814|Homo sapiens ADAM15 isoform 2 protein.     40   0.013
AY560593-1|AAS72991.1|  772|Homo sapiens ADAM15 isoform 1 protein.     40   0.013
AY518542-1|AAR99331.1|  772|Homo sapiens ADAM-15 precursor protein.    40   0.013
AL691442-13|CAI15327.1|  814|Homo sapiens ADAM metallopeptidase ...    40   0.013
AL451085-36|CAI13274.1|  814|Homo sapiens ADAM metallopeptidase ...    40   0.013
AF314227-11|AAS72298.1|  797|Homo sapiens ADAM15 isoform 8 protein.    40   0.013
AF314227-10|AAS48596.1|  821|Homo sapiens ADAM15 isoform 7a prot...    40   0.013
AF314227-9|AAS48597.1|  822|Homo sapiens ADAM15 isoform 7b protein.    40   0.013
AF314227-8|AAS48590.1|  772|Homo sapiens ADAM15 isoform 1 protein.     40   0.013
AF314227-7|AAS48591.1|  796|Homo sapiens ADAM15 isoform 3a protein.    40   0.013
AF314227-6|AAM44189.1|  814|Homo sapiens ADAM15 isoform 2 protein.     40   0.013
AF314227-5|AAS48593.1|  838|Homo sapiens ADAM15 isoform 5 protein.     40   0.013
AF314227-4|AAS48594.1|  862|Homo sapiens ADAM15 isoform 6a protein.    40   0.013
AF314227-3|AAS48592.1|  839|Homo sapiens ADAM15 isoform 4a protein.    40   0.013
AF314227-2|AAS48595.1|  863|Homo sapiens ADAM15 isoform 6b protein.    40   0.013
AB209157-1|BAD92394.1|  859|Homo sapiens ADAM15 isoform 6a varia...    40   0.013
BC109025-1|AAI09026.1|  721|Homo sapiens ADAM21 protein protein.       39   0.017
BC109024-1|AAI09025.1|  722|Homo sapiens ADAM metallopeptidase d...    39   0.017
AF158644-1|AAD55255.1|  722|Homo sapiens metalloproteinase-disin...    39   0.017
BC060804-1|AAH60804.1|  737|Homo sapiens ADAM metallopeptidase d...    38   0.053
AY358878-1|AAQ89237.1|  735|Homo sapiens ADAM-12 protein.              38   0.053
AL589787-6|CAI40683.1|  738|Homo sapiens ADAM metallopeptidase d...    38   0.053
AL589787-5|CAI40682.1|  909|Homo sapiens ADAM metallopeptidase d...    38   0.053
AF023477-1|AAC08703.2|  738|Homo sapiens meltrin-S protein.            38   0.053
AF023476-1|AAC08702.2|  909|Homo sapiens meltrin-L precursor pro...    38   0.053
AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein pr...    37   0.070
DQ202398-1|ABA43715.1|  465|Homo sapiens ADAM21-like protein pro...    37   0.093
AF029900-1|AAC52042.1|  542|Homo sapiens ADAM 21 protein.              37   0.093
AF171931-1|AAF03779.1|  787|Homo sapiens metallaproteinase-disin...    36   0.16 
AF171930-1|AAF03778.1|  766|Homo sapiens metallaproteinase-disin...    36   0.16 
AF171929-1|AAF03777.1|  820|Homo sapiens metallaproteinase-disin...    36   0.16 
AF134708-1|AAF22163.1|  820|Homo sapiens disintegrin and metallo...    36   0.16 
AC105914-1|AAY41055.1|  820|Homo sapiens unknown protein.              36   0.16 
BC103829-1|AAI03830.1|  276|Homo sapiens ADAMTS13 protein protein.     34   0.50 
BC103828-1|AAI03829.1|  276|Homo sapiens ADAMTS13 protein protein.     34   0.50 
AY532929-1|AAS54901.1|   90|Homo sapiens von Willebrand factor-c...    34   0.50 
Y13786-1|CAC20585.1|  918|Homo sapiens meltrin-beta/ADAM 19 homo...    34   0.66 
AF311317-1|AAK07852.1|  918|Homo sapiens disintegrin and metallo...    34   0.66 
AF134707-1|AAF22162.1|  857|Homo sapiens disintegrin and metallo...    34   0.66 
D26579-1|BAA05626.1|  824|Homo sapiens transmembrane protein pro...    33   0.87 
BC115404-1|AAI15405.1|  824|Homo sapiens ADAM8 protein protein.        33   0.87 
BC025378-1|AAH25378.2|  776|Homo sapiens ADAM metallopeptidase d...    31   6.1  
AF158643-1|AAD55254.1|  726|Homo sapiens metalloproteinase-disin...    31   6.1  
AF029899-1|AAC52041.1|  726|Homo sapiens ADAM 20 protein.              31   6.1  

>AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 36/83 (43%), Positives = 54/83 (65%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDE 184
           +SLE + +W +    + P  +   D  ++LTR   G PSG+APV G+C   RS A++ ++
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFG-PSGYAPVTGMCHPLRSCALNHED 388

Query: 185 GLTSAFVIAHELAHLLGLTHDGE 253
           G +SAFVIAHE  H+LG+ HDG+
Sbjct: 389 GFSSAFVIAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAPGKWC 535



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 413 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 465


>AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1223

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 36/83 (43%), Positives = 54/83 (65%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDE 184
           +SLE + +W +    + P  +   D  ++LTR   G PSG+APV G+C   RS A++ ++
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFG-PSGYAPVTGMCHPLRSCALNHED 388

Query: 185 GLTSAFVIAHELAHLLGLTHDGE 253
           G +SAFVIAHE  H+LG+ HDG+
Sbjct: 389 GFSSAFVIAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAPGKWC 535



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 413 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 465


>AJ345098-1|CAC87943.1| 1223|Homo sapiens
           metalloprotease-disintegrin protease protein.
          Length = 1223

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 36/83 (43%), Positives = 54/83 (65%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDE 184
           +SLE + +W +    + P  +   D  ++LTR   G PSG+APV G+C   RS A++ ++
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFG-PSGYAPVTGMCHPLRSCALNHED 388

Query: 185 GLTSAFVIAHELAHLLGLTHDGE 253
           G +SAFVIAHE  H+LG+ HDG+
Sbjct: 389 GFSSAFVIAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAPGKWC 535



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 413 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 465


>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motif 14 prec
           protein.
          Length = 1223

 Score = 80.6 bits (190), Expect = 6e-15
 Identities = 36/83 (43%), Positives = 54/83 (65%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDE 184
           +SLE + +W +    + P  +   D  ++LTR   G PSG+APV G+C   RS A++ ++
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFG-PSGYAPVTGMCHPLRSCALNHED 388

Query: 185 GLTSAFVIAHELAHLLGLTHDGE 253
           G +SAFVIAHE  H+LG+ HDG+
Sbjct: 389 GFSSAFVIAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAPGKWC 535



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 413 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 465


>AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 77.0 bits (181), Expect = 7e-14
 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W +    + P  +   D  ++LTR   G  G  G+APV G+C   RS A++ 
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNH 389

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFVIAHE  H+LG+ HDG+
Sbjct: 390 EDGFSSAFVIAHETGHVLGMEHDGQ 414



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 473 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 530

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 531 ECAPGKWC 538



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 416 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 468


>AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 14 protein.
          Length = 1226

 Score = 77.0 bits (181), Expect = 7e-14
 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W +    + P  +   D  ++LTR   G  G  G+APV G+C   RS A++ 
Sbjct: 330 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNH 389

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFVIAHE  H+LG+ HDG+
Sbjct: 390 EDGFSSAFVIAHETGHVLGMEHDGQ 414



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 473 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 530

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 531 ECAPGKWC 538



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 416 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 468


>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
          Length = 1159

 Score = 77.0 bits (181), Expect = 7e-14
 Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W +    + P  +   D  ++LTR   G  G  G+APV G+C   RS A++ 
Sbjct: 263 RSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGYAPVTGMCHPLRSCALNH 322

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFVIAHE  H+LG+ HDG+
Sbjct: 323 EDGFSSAFVIAHETGHVLGMEHDGQ 347



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 406 ELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 463

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 464 ECAPGKWC 471



 Score = 42.7 bits (96), Expect = 0.001
 Identities = 20/53 (37%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H F WS CSK +       + CL +      W
Sbjct: 349 NGCADETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYDCLLDDPFDPAW 401


>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
           protein.
          Length = 1211

 Score = 71.7 bits (168), Expect = 3e-12
 Identities = 37/87 (42%), Positives = 55/87 (63%), Gaps = 4/87 (4%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPE-GSTGW-DATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAI 172
           +SLE + +W Y  L + P+ G   + D  I+LTR   G  G  G+APV G+C   RS  +
Sbjct: 337 QSLENVCRWAY--LQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTL 394

Query: 173 DRDEGLTSAFVIAHELAHLLGLTHDGE 253
           + ++G +SAFV+AHE  H+LG+ HDG+
Sbjct: 395 NHEDGFSSAFVVAHETGHVLGMEHDGQ 421



 Score = 42.3 bits (95), Expect = 0.002
 Identities = 18/53 (33%), Positives = 25/53 (47%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GS+MAP V A  H F WS CS+++       + CL +      W
Sbjct: 423 NRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELSRYLHSYDCLLDDPFAHDW 475



 Score = 39.9 bits (89), Expect = 0.010
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           +L    ++M+EQCR +FG G+ +C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 480 QLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 537

Query: 603 PCGQNQWC 626
            C   + C
Sbjct: 538 MCAPGKHC 545


>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
          Length = 1205

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W  +        S   D  I+LTR   G  G  G+APV G+C   RS  ++ 
Sbjct: 327 RSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNH 386

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFV+AHE  H+LG+ HDG+
Sbjct: 387 EDGFSSAFVVAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+ +C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAAGKWC 535



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 18/53 (33%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H + WS CS ++       + CL +      W
Sbjct: 413 NRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFDHDW 465


>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 3 protein.
          Length = 1205

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W  +        S   D  I+LTR   G  G  G+APV G+C   RS  ++ 
Sbjct: 327 RSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNH 386

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFV+AHE  H+LG+ HDG+
Sbjct: 387 EDGFSSAFVVAHETGHVLGMEHDGQ 411



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+ +C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 470 ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 527

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 528 ECAAGKWC 535



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 18/53 (33%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H + WS CS ++       + CL +      W
Sbjct: 413 NRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFDHDW 465


>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
          Length = 1201

 Score = 71.3 bits (167), Expect = 4e-12
 Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
 Frame = +2

Query: 5   KSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAIDR 178
           +SLE + +W  +        S   D  I+LTR   G  G  G+APV G+C   RS  ++ 
Sbjct: 323 RSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNH 382

Query: 179 DEGLTSAFVIAHELAHLLGLTHDGE 253
           ++G +SAFV+AHE  H+LG+ HDG+
Sbjct: 383 EDGFSSAFVVAHETGHVLGMEHDGQ 407



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           EL    ++MDEQCR +FG G+ +C + R     +   C  P      C  +K+ PPL+GT
Sbjct: 466 ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYF-CK-TKKGPPLDGT 523

Query: 603 PCGQNQWC 626
            C   +WC
Sbjct: 524 ECAAGKWC 531



 Score = 40.7 bits (91), Expect = 0.006
 Identities = 18/53 (33%), Positives = 24/53 (45%)
 Frame = +1

Query: 253 SNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERTLTRVW 411
           + C  E   GSVMAP V A  H + WS CS ++       + CL +      W
Sbjct: 409 NRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFDHDW 461


>BC093777-1|AAH93777.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172
           +L+   KW ++H     +    +DA I  TR  L G       G A VG +C+  RS A+
Sbjct: 337 TLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAV 396

Query: 173 DRDEGLTSAFVIAHELAHLLGLTHD 247
             D+GL +AF +AHE+ HLLGL+HD
Sbjct: 397 IEDDGLHAAFTVAHEIGHLLGLSHD 421



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%)
 Frame = +3

Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           G +EL    +   +QC   FG  +SVC  +    R   C V     + C  +K+ P +EG
Sbjct: 482 GPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 539

Query: 600 TPCGQNQWCV 629
           TPCG+ + C+
Sbjct: 540 TPCGKGRICL 549


>BC093775-1|AAH93775.1|  930|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
          Length = 930

 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172
           +L+   KW ++H     +    +DA I  TR  L G       G A VG +C+  RS A+
Sbjct: 337 TLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAV 396

Query: 173 DRDEGLTSAFVIAHELAHLLGLTHD 247
             D+GL +AF +AHE+ HLLGL+HD
Sbjct: 397 IEDDGLHAAFTVAHEIGHLLGLSHD 421



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%)
 Frame = +3

Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           G +EL    +   +QC   FG  +SVC  +    R   C V     + C  +K+ P +EG
Sbjct: 482 GPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 539

Query: 600 TPCGQNQWCV 629
           TPCG+ + C+
Sbjct: 540 TPCGKGRICL 549


>AF142099-1|AAD49577.1|  930|Homo sapiens aggrecanase-2 protein.
          Length = 930

 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172
           +L+   KW ++H     +    +DA I  TR  L G       G A VG +C+  RS A+
Sbjct: 337 TLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAV 396

Query: 173 DRDEGLTSAFVIAHELAHLLGLTHD 247
             D+GL +AF +AHE+ HLLGL+HD
Sbjct: 397 IEDDGLHAAFTVAHEIGHLLGLSHD 421



 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%)
 Frame = +3

Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           G +EL    +   +QC   FG  +SVC  +    R   C V     + C  +K+ P +EG
Sbjct: 482 GPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 539

Query: 600 TPCGQNQWCV 629
           TPCG+ + C+
Sbjct: 540 TPCGKGRICL 549


>AB209515-1|BAD92752.1|  847|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 847

 Score = 63.3 bits (147), Expect = 9e-10
 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 14/96 (14%)
 Frame = +2

Query: 5   KSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGG 142
           KSL++  KW     N+  H   +PE G    D  + +TR  +        G  G APVGG
Sbjct: 63  KSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGG 122

Query: 143 VCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           +C + RS +++ D GL +AF IAHE+ H  G+ HDG
Sbjct: 123 MCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDG 158


>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 1077

 Score = 62.5 bits (145), Expect = 2e-09
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 14/96 (14%)
 Frame = +2

Query: 5   KSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGG 142
           KSL++  KW     N+  H   +PE G    D  + +TR  +        G  G APVGG
Sbjct: 283 KSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGG 342

Query: 143 VCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           +C + RS +++ D GL  AF IAHE+ H  G+ HDG
Sbjct: 343 MCERERSCSVNEDIGLPQAFTIAHEIGHTFGMNHDG 378


>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 18 protein.
          Length = 1221

 Score = 62.1 bits (144), Expect = 2e-09
 Identities = 29/62 (46%), Positives = 38/62 (61%)
 Frame = +2

Query: 68  TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           TG+D   W  +++     GFAP+ G+C+K RS  I+ D GL  AF IAHE  H  G+ HD
Sbjct: 390 TGFDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 447

Query: 248 GE 253
           GE
Sbjct: 448 GE 449



 Score = 32.3 bits (70), Expect = 2.0
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           +L   ++  D QC+ +FG    +C    V+   ++  C      C T    K  P  EGT
Sbjct: 509 KLPGQIYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCET----KFMPAAEGT 564

Query: 603 PCGQNQWC 626
            CG + WC
Sbjct: 565 VCGLSMWC 572


>DQ266047-1|ABB70405.1|  570|Homo sapiens ADAMTS16s alternative
           splice form protein.
          Length = 570

 Score = 60.9 bits (141), Expect = 5e-09
 Identities = 29/62 (46%), Positives = 37/62 (59%)
 Frame = +2

Query: 68  TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           TG D   W  +++     GFAP+ G+C+K RS  I+ D GL  AF IAHE  H  G+ HD
Sbjct: 387 TGLDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 444

Query: 248 GE 253
           GE
Sbjct: 445 GE 446


>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease
           disintegrin 16 with thrombospondin type I motif protein.
          Length = 1072

 Score = 60.9 bits (141), Expect = 5e-09
 Identities = 29/62 (46%), Positives = 37/62 (59%)
 Frame = +2

Query: 68  TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           TG D   W  +++     GFAP+ G+C+K RS  I+ D GL  AF IAHE  H  G+ HD
Sbjct: 387 TGLDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 444

Query: 248 GE 253
           GE
Sbjct: 445 GE 446



 Score = 31.1 bits (67), Expect = 4.6
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
 Frame = +3

Query: 426 KELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           ++L   ++  + QC+ +FGE   +C     +   +A  C      C T    K  P  EG
Sbjct: 505 EKLPGELYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCET----KFMPAAEG 560

Query: 600 TPCGQNQWC 626
           T CG + WC
Sbjct: 561 TICGHDMWC 569


>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
          Length = 1081

 Score = 60.9 bits (141), Expect = 5e-09
 Identities = 29/62 (46%), Positives = 37/62 (59%)
 Frame = +2

Query: 68  TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           TG+D   W  +++     GFAP  G+C+K RS  I+ D GL  AF IAHE  H  G+ HD
Sbjct: 389 TGFDICSW--KNEPCDTLGFAPTSGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 446

Query: 248 GE 253
           GE
Sbjct: 447 GE 448



 Score = 32.3 bits (70), Expect = 2.0
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAPPLEGT 602
           +L   ++  D QC+ +FG    +C    V+   ++  C      C T    K  P  EGT
Sbjct: 508 KLPGQIYDADTQCKWQFGAKAKLCSLGFVKDICKSLWCHRVGHRCET----KFMPAAEGT 563

Query: 603 PCGQNQWC 626
            CG + WC
Sbjct: 564 VCGLSMWC 571


>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
          Length = 1021

 Score = 60.9 bits (141), Expect = 5e-09
 Identities = 29/62 (46%), Positives = 37/62 (59%)
 Frame = +2

Query: 68  TGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           TG D   W  +++     GFAP+ G+C+K RS  I+ D GL  AF IAHE  H  G+ HD
Sbjct: 184 TGLDICSW--KNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHD 241

Query: 248 GE 253
           GE
Sbjct: 242 GE 243



 Score = 31.1 bits (67), Expect = 4.6
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
 Frame = +3

Query: 426 KELSNYVFTMDEQCRTEFGEGFSVCRS--VRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           ++L   ++  + QC+ +FGE   +C     +   +A  C      C T    K  P  EG
Sbjct: 302 EKLPGELYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCET----KFMPAAEG 357

Query: 600 TPCGQNQWC 626
           T CG + WC
Sbjct: 358 TICGHDMWC 366


>AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.
          Length = 837

 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 31/67 (46%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
 Frame = +2

Query: 62  GSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226
           G   +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF  AHEL H
Sbjct: 306 GPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGH 365

Query: 227 LLGLTHD 247
           +  + HD
Sbjct: 366 VFNMLHD 372



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 501

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 502 MGGRCLHMD 510


>AY692425-1|AAW47398.1|  468|Homo sapiens ADAMTS6 variant 3 protein.
          Length = 468

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 14/97 (14%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGST-------GWDATIWLTRSQLG-------GPSGFAPVG 139
           +KSL++  KW    L    +G+T         D  + +TR  +        G  G A V 
Sbjct: 319 DKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVA 378

Query: 140 GVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           G+C   RS +I+ D GL SAF IAHE+ H  G+ HDG
Sbjct: 379 GMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDG 415


>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 1117

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 14/97 (14%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGST-------GWDATIWLTRSQLG-------GPSGFAPVG 139
           +KSL++  KW    L    +G+T         D  + +TR  +        G  G A V 
Sbjct: 319 DKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVA 378

Query: 140 GVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           G+C   RS +I+ D GL SAF IAHE+ H  G+ HDG
Sbjct: 379 GMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDG 415


>AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease
           ADAMTS6 protein.
          Length = 860

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 14/97 (14%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGST-------GWDATIWLTRSQLG-------GPSGFAPVG 139
           +KSL++  KW    L    +G+T         D  + +TR  +        G  G A V 
Sbjct: 319 DKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVA 378

Query: 140 GVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           G+C   RS +I+ D GL SAF IAHE+ H  G+ HDG
Sbjct: 379 GMCEPERSCSINEDIGLGSAFTIAHEIVHNFGMNHDG 415


>BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 15 protein.
          Length = 950

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/63 (42%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           WD  I  TR  L G +     G A VG +C   RS ++  D+GL SAF  AHEL H+  +
Sbjct: 310 WDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNM 369

Query: 239 THD 247
            HD
Sbjct: 370 PHD 372



 Score = 31.5 bits (68), Expect = 3.5
 Identities = 16/68 (23%), Positives = 32/68 (47%)
 Frame = +3

Query: 426 KELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTP 605
           ++L    +T+ +QC   FG G   C  +++  +    G      + C  ++  P  +GT 
Sbjct: 435 EDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQ-MVCQ-TRHFPWADGTS 492

Query: 606 CGQNQWCV 629
           CG+ + C+
Sbjct: 493 CGEGKLCL 500


>BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 33/74 (44%), Positives = 38/74 (51%), Gaps = 7/74 (9%)
 Frame = +2

Query: 47  MKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFV 205
           +  PE S    +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF 
Sbjct: 299 LNTPENSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFT 358

Query: 206 IAHELAHLLGLTHD 247
            AHEL H+  + HD
Sbjct: 359 AAHELGHVFNVLHD 372



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 501

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 502 MGGRCLHMD 510


>AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.
          Length = 837

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF  AHEL H+  +
Sbjct: 310 FDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNM 369

Query: 239 THD 247
            HD
Sbjct: 370 LHD 372



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 501

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 502 MGGRCLHMD 510


>AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF  AHEL H+  +
Sbjct: 310 FDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNM 369

Query: 239 THD 247
            HD
Sbjct: 370 LHD 372



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 501

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 502 MGGRCLHMD 510


>AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease
           disintegrin 15 with thrombospondin domains protein.
          Length = 950

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/63 (42%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           WD  I  TR  L G +     G A VG +C   RS ++  D+GL SAF  AHEL H+  +
Sbjct: 310 WDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNM 369

Query: 239 THD 247
            HD
Sbjct: 370 PHD 372



 Score = 31.5 bits (68), Expect = 3.5
 Identities = 16/68 (23%), Positives = 32/68 (47%)
 Frame = +3

Query: 426 KELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTP 605
           ++L    +T+ +QC   FG G   C  +++  +    G      + C  ++  P  +GT 
Sbjct: 435 EDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQ-MVCQ-TRHFPWADGTS 492

Query: 606 CGQNQWCV 629
           CG+ + C+
Sbjct: 493 CGEGKLCL 500


>AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.
          Length = 837

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF  AHEL H+  +
Sbjct: 310 FDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNM 369

Query: 239 THD 247
            HD
Sbjct: 370 LHD 372



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 443 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 501

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 502 MGGRCLHMD 510


>AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.
          Length = 849

 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           +D  I  TR  L G S     G A VG VC   RS AI  D+GL SAF  AHEL H+  +
Sbjct: 322 FDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNM 381

Query: 239 THD 247
            HD
Sbjct: 382 LHD 384



 Score = 30.3 bits (65), Expect = 8.1
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 1/69 (1%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           +  D QC+  FG     C  +     A  C         C  +K +P  +GTPCG  Q C
Sbjct: 455 YDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQ-TKHSPWADGTPCGPAQAC 513

Query: 627 V-DRVLRXD 650
           +  R L  D
Sbjct: 514 MGGRCLHMD 522


>BC036515-1|AAH36515.1|  967|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 1 protein.
          Length = 967

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 335 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 394

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 395 AAFTTAHELGHVFNMPHD 412



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 476 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 534

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 535 GEGKWCIN 542


>AP001697-1|BAA95502.1|  967|Homo sapiens metalloprotease with
           thrombospondin type 1 motifs protein.
          Length = 967

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 335 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 394

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 395 AAFTTAHELGHVFNMPHD 412



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 476 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 534

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 535 GEGKWCIN 542


>AF207664-1|AAF23772.1|  967|Homo sapiens matrix metalloprotease
           protein.
          Length = 967

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 335 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 394

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 395 AAFTTAHELGHVFNMPHD 412



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 476 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 534

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 535 GEGKWCIN 542


>AF170084-1|AAF15317.1|  967|Homo sapiens metalloproteinase with
           thrombospondin type 1 motifs ADAMTS1 protein.
          Length = 967

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 335 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 394

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 395 AAFTTAHELGHVFNMPHD 412



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 476 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 534

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 535 GEGKWCIN 542


>AF060152-1|AAD48080.1|  950|Homo sapiens METH1 protein protein.
          Length = 950

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 318 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 377

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 378 AAFTTAHELGHVFNMPHD 395



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 459 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 517

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 518 GEGKWCIN 525


>AB037767-1|BAA92584.1|  999|Homo sapiens KIAA1346 protein protein.
          Length = 999

 Score = 54.0 bits (124), Expect = 6e-07
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
 Frame = +2

Query: 29  WNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAIDRDEGLT 193
           W  +H       +  +D  I  TR  L G       G A VG VC  +RS ++  D+GL 
Sbjct: 367 WQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGTVCDPSRSCSVIEDDGLQ 426

Query: 194 SAFVIAHELAHLLGLTHD 247
           +AF  AHEL H+  + HD
Sbjct: 427 AAFTTAHELGHVFNMPHD 444



 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 508 DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 566

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 567 GEGKWCIN 574


>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 7 protein.
          Length = 1686

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160
           + +L++  KW     MK        D  I LTR  L           G + V G+C   R
Sbjct: 311 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 370

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           S +I+ D GL  AF +AHEL H  G+ HDG
Sbjct: 371 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 400



 Score = 37.9 bits (84), Expect = 0.040
 Identities = 19/62 (30%), Positives = 31/62 (50%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623
           ++ +  QCR ++G   + C  +        C V T    TC  SK    ++GT CG+N+W
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGT----TCH-SKLDAAVDGTRCGENKW 521

Query: 624 CV 629
           C+
Sbjct: 522 CL 523


>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
          Length = 1686

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160
           + +L++  KW     MK        D  I LTR  L           G + V G+C   R
Sbjct: 311 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 370

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           S +I+ D GL  AF +AHEL H  G+ HDG
Sbjct: 371 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 400



 Score = 37.9 bits (84), Expect = 0.040
 Identities = 19/62 (30%), Positives = 31/62 (50%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623
           ++ +  QCR ++G   + C  +        C V T    TC  SK    ++GT CG+N+W
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGT----TCH-SKLDAAVDGTRCGENKW 521

Query: 624 CV 629
           C+
Sbjct: 522 CL 523


>AF140675-1|AAD56358.1|  997|Homo sapiens zinc metalloprotease
           ADAMTS7 protein.
          Length = 997

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160
           + +L++  KW     MK        D  I LTR  L           G + V G+C   R
Sbjct: 311 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 370

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           S +I+ D GL  AF +AHEL H  G+ HDG
Sbjct: 371 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 400



 Score = 37.9 bits (84), Expect = 0.040
 Identities = 19/62 (30%), Positives = 31/62 (50%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623
           ++ +  QCR ++G   + C  +        C V T    TC  SK    ++GT CG+N+W
Sbjct: 467 LYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGT----TCH-SKLDAAVDGTRCGENKW 521

Query: 624 CV 629
           C+
Sbjct: 522 CL 523


>AB209497-1|BAD92734.1|  527|Homo sapiens a disintegrin and
           metalloprotease with thrombospondin motifs-7
           preproprotein va protein.
          Length = 527

 Score = 53.2 bits (122), Expect = 1e-06
 Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTR 160
           + +L++  KW     MK        D  I LTR  L           G + V G+C   R
Sbjct: 276 DNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHR 335

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDG 250
           S +I+ D GL  AF +AHEL H  G+ HDG
Sbjct: 336 SCSINEDTGLPLAFTVAHELGHSFGIQHDG 365


>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
          Length = 1509

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS---GFAPVGGVCTKTR 160
           EK+L +  KW      K        D  + LTR  +      P    G + + G+C   R
Sbjct: 315 EKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHR 374

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           S  I+ D GL  AF IAHEL H  G+ HDG+
Sbjct: 375 SCNINEDSGLPLAFTIAHELGHSFGIQHDGK 405



 Score = 34.3 bits (75), Expect = 0.50
 Identities = 16/62 (25%), Positives = 29/62 (46%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623
           ++ +  QC+ ++G   + C+ V    +   C V    C     SK     +GT CG+ +W
Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVK-GFCR----SKLDAAADGTQCGEKKW 525

Query: 624 CV 629
           C+
Sbjct: 526 CM 527


>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
           metalloprotease (reprolysin type) with thrombospondin ty
           protein.
          Length = 1593

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS---GFAPVGGVCTKTR 160
           EK+L +  KW      K        D  + LTR  +      P    G + + G+C   R
Sbjct: 315 EKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHR 374

Query: 161 SAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           S  I+ D GL  AF IAHEL H  G+ HDG+
Sbjct: 375 SCNINEDSGLPLAFTIAHELGHSFGIQHDGK 405



 Score = 34.3 bits (75), Expect = 0.50
 Identities = 16/62 (25%), Positives = 29/62 (46%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQW 623
           ++ +  QC+ ++G   + C+ V    +   C V    C     SK     +GT CG+ +W
Sbjct: 471 IYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVK-GFCR----SKLDAAADGTQCGEKKW 525

Query: 624 CV 629
           C+
Sbjct: 526 CM 527


>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 17 protein.
          Length = 1095

 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 22/44 (50%), Positives = 27/44 (61%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           G A +GGVC+  R   +  D GL  AF IAHEL H LG+ HD +
Sbjct: 359 GIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDD 402



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           ++ +EQC+  FG   + CR++   L   G         +C  +K  PPL+GT CG ++WC
Sbjct: 470 YSANEQCQILFGMNATFCRNMEH-LMCAGLWCLVEGDTSCK-TKLDPPLDGTECGADKWC 527


>AK131344-1|BAD18500.1|  502|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16363 fis, clone THYMU2031139, weakly  similar
           to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
           mRNA. ).
          Length = 502

 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 22/44 (50%), Positives = 27/44 (61%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           G A +GGVC+  R   +  D GL  AF IAHEL H LG+ HD +
Sbjct: 116 GIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDD 159



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           ++ +EQC+  FG   + CR++   L   G         +C  +K  PPL+GT CG ++WC
Sbjct: 227 YSANEQCQILFGMNATFCRNMEH-LMCAGLWCLVEGDTSCK-TKLDPPLDGTECGADKWC 284


>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
           disintegrin 17, with thrombospondin domains protein.
          Length = 1095

 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 22/44 (50%), Positives = 27/44 (61%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           G A +GGVC+  R   +  D GL  AF IAHEL H LG+ HD +
Sbjct: 359 GIAYLGGVCSAKRKCVLAEDNGLNLAFTIAHELGHNLGMNHDDD 402



 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/60 (33%), Positives = 32/60 (53%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           ++ +EQC+  FG   + CR++   L   G         +C  +K  PPL+GT CG ++WC
Sbjct: 470 YSANEQCQILFGMNATFCRNMEH-LMCAGLWCLVEGDTSCK-TKLDPPLDGTECGADKWC 527


>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
          Length = 1207

 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 18/102 (17%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLP----EGSTGW-------DATIWLTRSQL----GGPS---GF 127
           EK LE+  KW +    K      E ST W       DA I +TR         P    G 
Sbjct: 394 EKMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPCDTVGI 453

Query: 128 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGE 253
           A + G+C++ R   I  D GL  AF IAHE+ H +G+ HD +
Sbjct: 454 AYLSGMCSEKRKCIIAEDNGLNLAFTIAHEMGHNMGINHDND 495



 Score = 36.7 bits (81), Expect = 0.093
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +T DEQC+  FG   S C+ ++  +   G          C  +K  PP++GT C
Sbjct: 557 KLPGMTYTADEQCQILFGPLASFCQEMQHVI-CTGLWCKVEGEKECR-TKLDPPMDGTDC 614

Query: 609 GQNQWC 626
              +WC
Sbjct: 615 DLGKWC 620


>AP001698-1|BAA95504.1|  412|Homo sapiens disintegrin-like and
           metalloprotease with thrombospondin type 1 motif, 5
           protein.
          Length = 412

 Score = 50.0 bits (114), Expect = 9e-06
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
 Frame = +2

Query: 8   SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGVCTKTRSAAI 172
           +L+   KW ++H     +    +DA I  TR  L G       G A VG +C+  RS A+
Sbjct: 337 TLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAV 396

Query: 173 DRDEGLTSAFVIAHEL 220
             D+GL +AF +AHE+
Sbjct: 397 IEDDGLHAAFTVAHEI 412


>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 9 protein.
          Length = 1935

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 20/42 (47%), Positives = 27/42 (64%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G A +G +C   RS +I  D GL++AF IAHEL H+  + HD
Sbjct: 404 GLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHD 445


>BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.
          Length = 676

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPSGF------APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235
           +D  I LTR    G  G       A +G +C   +S ++  DEGL +A  +AHEL H+L 
Sbjct: 98  YDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLS 157

Query: 236 LTHD 247
           + HD
Sbjct: 158 MPHD 161



 Score = 32.7 bits (71), Expect = 1.5
 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVC--RSVRFGLRAQGCGVPTA--LCLTCAGSKRAPPLEGTPCG 611
           ++ +D+QCR  FG  F  C   S +       C    A  LC T  GS   P  +GTPCG
Sbjct: 232 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGS--LPWADGTPCG 289

Query: 612 QNQWC 626
               C
Sbjct: 290 PGHLC 294


>BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.
          Length = 918

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPSGF------APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235
           +D  I LTR    G  G       A +G +C   +S ++  DEGL +A  +AHEL H+L 
Sbjct: 340 YDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLS 399

Query: 236 LTHD 247
           + HD
Sbjct: 400 MPHD 403



 Score = 32.7 bits (71), Expect = 1.5
 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVC--RSVRFGLRAQGCGVPTA--LCLTCAGSKRAPPLEGTPCG 611
           ++ +D+QCR  FG  F  C   S +       C    A  LC T  GS   P  +GTPCG
Sbjct: 474 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGS--LPWADGTPCG 531

Query: 612 QNQWC 626
               C
Sbjct: 532 PGHLC 536


>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 9B
           protein.
          Length = 1935

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 20/42 (47%), Positives = 27/42 (64%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G A +G +C   RS +I  D GL++AF IAHEL H+  + HD
Sbjct: 404 GLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHD 445


>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
           metalloproteinase with thrombospondin repeats protein.
          Length = 1072

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 20/42 (47%), Positives = 27/42 (64%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G A +G +C   RS +I  D GL++AF IAHEL H+  + HD
Sbjct: 404 GLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHD 445


>AF175283-1|AAF25806.1|  246|Homo sapiens zinc metalloendopeptidase
           protein.
          Length = 246

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPSGF------APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235
           +D  I LTR    G  G       A +G +C   +S ++  DEGL +A  +AHEL H+L 
Sbjct: 118 YDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLS 177

Query: 236 LTHD 247
           + HD
Sbjct: 178 MPHD 181


>AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.
          Length = 890

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
 Frame = +2

Query: 74  WDATIWLTRSQLGGPSGF------APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLG 235
           +D  I LTR    G  G       A +G +C   +S ++  DEGL +A  +AHEL H+L 
Sbjct: 312 YDTAILLTRQNFCGQEGLCDTLGVADIGTICDPNKSCSVIEDEGLQAAHTLAHELGHVLS 371

Query: 236 LTHD 247
           + HD
Sbjct: 372 MPHD 375



 Score = 32.7 bits (71), Expect = 1.5
 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVC--RSVRFGLRAQGCGVPTA--LCLTCAGSKRAPPLEGTPCG 611
           ++ +D+QCR  FG  F  C   S +       C    A  LC T  GS   P  +GTPCG
Sbjct: 446 LYQLDQQCRQIFGPDFRHCPNTSAQDVCAQLWCHTDGAEPLCHTKNGS--LPWADGTPCG 503

Query: 612 QNQWC 626
               C
Sbjct: 504 PGHLC 508


>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
          Length = 1471

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 20/42 (47%), Positives = 27/42 (64%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G A +G +C   RS +I  D GL++AF IAHEL H+  + HD
Sbjct: 246 GLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHD 287


>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
          Length = 1502

 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 20/42 (47%), Positives = 28/42 (66%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G + +G +C   +S  I+ ++GL SAF IAHEL H LG+ HD
Sbjct: 373 GLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD 414



 Score = 31.9 bits (69), Expect = 2.6
 Identities = 18/66 (27%), Positives = 27/66 (40%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           EL    +  ++QC   FG G  +C  +   +    C     L   C  ++  PP +GT C
Sbjct: 477 ELPGSRYDGNKQCELAFGPGSQMCPHINICMHLW-CTSTEKLHKGCF-TQHVPPADGTDC 534

Query: 609 GQNQWC 626
           G    C
Sbjct: 535 GPGMHC 540


>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
          Length = 1908

 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 20/42 (47%), Positives = 28/42 (66%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G + +G +C   +S  I+ ++GL SAF IAHEL H LG+ HD
Sbjct: 373 GLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD 414



 Score = 31.9 bits (69), Expect = 2.6
 Identities = 18/66 (27%), Positives = 27/66 (40%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           EL    +  ++QC   FG G  +C  +   +    C     L   C  ++  PP +GT C
Sbjct: 477 ELPGSRYDGNKQCELAFGPGSQMCPHINICMHLW-CTSTEKLHKGCF-TQHVPPADGTDC 534

Query: 609 GQNQWC 626
           G    C
Sbjct: 535 GPGMHC 540


>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
           metalloprotease with thrombospondin type 1 motifs 20
           protein.
          Length = 1911

 Score = 47.6 bits (108), Expect = 5e-05
 Identities = 20/42 (47%), Positives = 28/42 (66%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHD 247
           G + +G +C   +S  I+ ++GL SAF IAHEL H LG+ HD
Sbjct: 373 GLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD 414



 Score = 31.9 bits (69), Expect = 2.6
 Identities = 18/66 (27%), Positives = 27/66 (40%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           EL    +  ++QC   FG G  +C  +   +    C     L   C  ++  PP +GT C
Sbjct: 477 ELPGSRYDGNKQCELAFGPGSQMCPHINICMHLW-CTSTEKLHKGCF-TQHVPPADGTDC 534

Query: 609 GQNQWC 626
           G    C
Sbjct: 535 GPGMHC 540


>AK128469-1|BAC87455.1|  327|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46613 fis, clone TKIDN2011160, moderately
           similar to ADAM-TS 3 precursor (EC 3.4.24.-). ).
          Length = 327

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
 Frame = +3

Query: 453 MDEQCRTEFGEGFSVCRSVRF--GLRAQGCGVPTALCLTCAGSKRAPPLEGTPCGQNQWC 626
           MDEQCR +FG G+  C + R     +   C  P      C  +K+ PPL+GT C   +WC
Sbjct: 1   MDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYF-CK-TKKGPPLDGTECAPGKWC 58


>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
           factor-cleaving protease precursor protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.1 bits (72), Expect = 1.1
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQ 614
           + + +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG 
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGV 331

Query: 615 NQWC 626
            +WC
Sbjct: 332 EKWC 335


>AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1371

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
           with thrombospondin type 1 motif, 13 protein.
          Length = 1340

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.1 bits (72), Expect = 1.1
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQ 614
           + + +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG 
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGV 331

Query: 615 NQWC 626
            +WC
Sbjct: 332 EKWC 335


>AJ420811-1|CAD12730.1|  344|Homo sapiens ADAMTS-13 protein,
           truncated variant protein.
          Length = 344

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236


>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
           2 protein.
          Length = 1371

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
          Length = 1340

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.1 bits (72), Expect = 1.1
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
 Frame = +3

Query: 444 VFTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQ 614
           + + +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG 
Sbjct: 273 LLSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGV 331

Query: 615 NQWC 626
            +WC
Sbjct: 332 EKWC 335


>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
           factor-cleaving protease protein.
          Length = 1427

 Score = 45.2 bits (102), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGL 238
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H  GL
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGL 232

Query: 239 THDG 250
            HDG
Sbjct: 233 EHDG 236



 Score = 33.9 bits (74), Expect = 0.66
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
 Frame = +3

Query: 447 FTMDEQCRTEFGEGFSVCRSVRFGL---RAQGCGVPTALCLTCAGSKRAPPLEGTPCGQN 617
           ++ +EQCR  FG     C   R  L   +A  C        +C+     P L+GT CG  
Sbjct: 305 YSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCS-RLLVPLLDGTECGVE 363

Query: 618 QWC 626
           +WC
Sbjct: 364 KWC 366


>AP001697-2|BAA95503.1|  517|Homo sapiens disintegrin-like and
           metalloprotease with thrombospondin type 1 motif, 5
           protein.
          Length = 517

 Score = 44.8 bits (101), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%)
 Frame = +3

Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           G +EL    +   +QC   FG  +SVC  +    R   C V     + C  +K+ P +EG
Sbjct: 69  GPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 126

Query: 600 TPCGQNQWCV 629
           TPCG+ + C+
Sbjct: 127 TPCGKGRICL 136


>AF141293-1|AAF02493.1|  518|Homo sapiens ADAMTS5 protein protein.
          Length = 518

 Score = 44.0 bits (99), Expect = 6e-04
 Identities = 23/70 (32%), Positives = 34/70 (48%)
 Frame = +3

Query: 420 GAKELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEG 599
           G +EL    +   +QC   FG  +SVC       R   C V     + C  +K+ P +EG
Sbjct: 70  GPEELPGQTYDATQQCNLTFGPEYSVCPGXDVCARLW-CAVVRQGQMVCL-TKKLPAVEG 127

Query: 600 TPCGQNQWCV 629
           TPCG+ + C+
Sbjct: 128 TPCGKGRICL 137


>U41766-1|AAC50403.1|  819|Homo sapiens
           metalloprotease/disintegrin/cysteine-rich protein
           precursor protein.
          Length = 819

 Score = 40.7 bits (91), Expect = 0.006
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           D+   + +   GG +G A VG VC+++ +  I+    +T    A ++AHEL H LG+ HD
Sbjct: 299 DSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHD 358


>D14665-1|BAA03499.2|  703|Homo sapiens KIAA0021 protein protein.
          Length = 703

 Score = 40.7 bits (91), Expect = 0.006
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           D+   + +   GG +G A VG VC+++ +  I+    +T    A ++AHEL H LG+ HD
Sbjct: 183 DSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHD 242


>BC126406-1|AAI26407.1|  712|Homo sapiens ADAM9 protein protein.
          Length = 712

 Score = 40.7 bits (91), Expect = 0.006
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           D+   + +   GG +G A VG VC+++ +  I+    +T    A ++AHEL H LG+ HD
Sbjct: 299 DSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHD 358


>AF495383-1|AAM49575.1|  655|Homo sapiens
           disintegrin/metalloproteinase domain 9 short protein
           precursor protein.
          Length = 655

 Score = 40.7 bits (91), Expect = 0.006
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           D+   + +   GG +G A VG VC+++ +  I+    +T    A ++AHEL H LG+ HD
Sbjct: 299 DSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHD 358


>DQ995342-1|ABI97387.1|  813|Homo sapiens ADAM metallopeptidase
           domain 33 protein.
          Length = 813

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AY358314-1|AAQ88680.1|  813|Homo sapiens Adam33 protein.
          Length = 813

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AL356755-2|CAI23465.1|  813|Homo sapiens ADAM metallopeptidase
           domain 33 protein.
          Length = 813

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AL356755-1|CAM28348.1|  812|Homo sapiens ADAM metallopeptidase
           domain 33 protein.
          Length = 812

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AL109804-2|CAI18840.1|  813|Homo sapiens ADAM metallopeptidase
           domain 33 protein.
          Length = 813

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AL109804-1|CAM26955.1|  812|Homo sapiens ADAM metallopeptidase
           domain 33 protein.
          Length = 812

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AF466288-1|AAM80483.1|  812|Homo sapiens a disintegrin and
           metalloprotease domain 33 protein.
          Length = 812

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AF466287-1|AAM80482.1|  812|Homo sapiens a disintegrin and
           metalloprotease domain 33 protein.
          Length = 812

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>AB055891-1|BAB83092.1|  813|Homo sapiens metalloprotease
           disintegrin protein.
          Length = 813

 Score = 40.3 bits (90), Expect = 0.008
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +2

Query: 98  RSQLGGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           R+  G   G APV G+C    S  +  D     + +A  +AHE+ H LGL+HD
Sbjct: 304 RAFQGATVGLAPVEGMCRAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHD 356


>U46005-1|AAC51112.1|  814|Homo sapiens MDC15 protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>U41767-1|AAC50404.1|  814|Homo sapiens metargidin precursor
           protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>BT009764-1|AAP88766.1|  814|Homo sapiens a disintegrin and
           metalloproteinase domain 15 (metargidin) protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>BC014566-1|AAH14566.1|  814|Homo sapiens ADAM metallopeptidase
           domain 15 (metargidin) protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY576417-1|AAS73000.1|  797|Homo sapiens ADAM15 isoform 8 protein.
          Length = 797

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560601-1|AAS72999.1|  822|Homo sapiens ADAM15 isoform 7b protein.
          Length = 822

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560600-1|AAS72998.1|  821|Homo sapiens ADAM15 isoform 7a protein.
          Length = 821

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560599-1|AAS72997.1|  863|Homo sapiens ADAM15 isoform 6b protein.
          Length = 863

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560598-1|AAS72996.1|  862|Homo sapiens ADAM15 isoform 6a protein.
          Length = 862

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560597-1|AAS72995.1|  838|Homo sapiens ADAM15 isoform 5 protein.
          Length = 838

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560596-1|AAS72994.1|  839|Homo sapiens ADAM15 isoform 4a protein.
          Length = 839

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560595-1|AAS72993.1|  796|Homo sapiens ADAM15 isoform 3a protein.
          Length = 796

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560594-1|AAS72992.1|  814|Homo sapiens ADAM15 isoform 2 protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY560593-1|AAS72991.1|  772|Homo sapiens ADAM15 isoform 1 protein.
          Length = 772

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AY518542-1|AAR99331.1|  772|Homo sapiens ADAM-15 precursor protein.
          Length = 772

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AL691442-13|CAI15327.1|  814|Homo sapiens ADAM metallopeptidase
           domain 15 protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AL451085-36|CAI13274.1|  814|Homo sapiens ADAM metallopeptidase
           domain 15 protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-11|AAS72298.1|  797|Homo sapiens ADAM15 isoform 8 protein.
          Length = 797

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-10|AAS48596.1|  821|Homo sapiens ADAM15 isoform 7a
           protein.
          Length = 821

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-9|AAS48597.1|  822|Homo sapiens ADAM15 isoform 7b protein.
          Length = 822

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-8|AAS48590.1|  772|Homo sapiens ADAM15 isoform 1 protein.
          Length = 772

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-7|AAS48591.1|  796|Homo sapiens ADAM15 isoform 3a protein.
          Length = 796

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-6|AAM44189.1|  814|Homo sapiens ADAM15 isoform 2 protein.
          Length = 814

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-5|AAS48593.1|  838|Homo sapiens ADAM15 isoform 5 protein.
          Length = 838

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-4|AAS48594.1|  862|Homo sapiens ADAM15 isoform 6a protein.
          Length = 862

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-3|AAS48592.1|  839|Homo sapiens ADAM15 isoform 4a protein.
          Length = 839

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AF314227-2|AAS48595.1|  863|Homo sapiens ADAM15 isoform 6b protein.
          Length = 863

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 280 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 334

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 335 HSTSILGVASSIAHELGHSLGLDHD 359


>AB209157-1|BAD92394.1|  859|Homo sapiens ADAM15 isoform 6a variant
           protein.
          Length = 859

 Score = 39.5 bits (88), Expect = 0.013
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
 Frame = +2

Query: 8   SLEAINKWNYRHLM-KLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCTKTRSAAIDRD 181
           +LE    W   HL+ +LP      D+   +T +   GP+ G A    +C+   S  ++ D
Sbjct: 277 TLENFLHWRRAHLLPRLPH-----DSAQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMD 331

Query: 182 EG---LTSAFVIAHELAHLLGLTHD 247
                L  A  IAHEL H LGL HD
Sbjct: 332 HSTSILGVASSIAHELGHSLGLDHD 356


>BC109025-1|AAI09026.1|  721|Homo sapiens ADAM21 protein protein.
          Length = 721

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181
           E+ L   ++W    L +L       DA     ++ L    G A V G+C       +D  
Sbjct: 272 EQVLNDFSQWKQISLSQLQH-----DAAHMFIKNSLISILGLAYVAGICRPPIDCGVDNF 326

Query: 182 EGLT-SAFV--IAHELAHLLGLTHDGE 253
           +G T S F   +AHEL H LG+ HD E
Sbjct: 327 QGDTWSLFANTVAHELGHTLGMQHDEE 353


>BC109024-1|AAI09025.1|  722|Homo sapiens ADAM metallopeptidase
           domain 21 protein.
          Length = 722

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181
           E+ L   ++W    L +L       DA     ++ L    G A V G+C       +D  
Sbjct: 273 EQVLNDFSQWKQISLSQLQH-----DAAHMFIKNSLISILGLAYVAGICRPPIDCGVDNF 327

Query: 182 EGLT-SAFV--IAHELAHLLGLTHDGE 253
           +G T S F   +AHEL H LG+ HD E
Sbjct: 328 QGDTWSLFANTVAHELGHTLGMQHDEE 354


>AF158644-1|AAD55255.1|  722|Homo sapiens
           metalloproteinase-disintegrin protein.
          Length = 722

 Score = 39.1 bits (87), Expect = 0.017
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181
           E+ L   ++W    L +L       DA     ++ L    G A V G+C       +D  
Sbjct: 273 EQVLNDFSQWKQISLSQLQH-----DAAHMFIKNSLISILGLAYVAGICRPPIDCGVDNF 327

Query: 182 EGLT-SAFV--IAHELAHLLGLTHDGE 253
           +G T S F   +AHEL H LG+ HD E
Sbjct: 328 QGDTWSLFANTVAHELGHTLGMQHDEE 354


>BC060804-1|AAH60804.1|  737|Homo sapiens ADAM metallopeptidase
           domain 12 (meltrin alpha) protein.
          Length = 737

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 310 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 358


>AY358878-1|AAQ89237.1|  735|Homo sapiens ADAM-12 protein.
          Length = 735

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 310 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 358


>AL589787-6|CAI40683.1|  738|Homo sapiens ADAM metallopeptidase
           domain 12 (meltrin alpha) protein.
          Length = 738

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 313 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 361


>AL589787-5|CAI40682.1|  909|Homo sapiens ADAM metallopeptidase
           domain 12 (meltrin alpha) protein.
          Length = 909

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 313 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 361


>AF023477-1|AAC08703.2|  738|Homo sapiens meltrin-S protein.
          Length = 738

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 313 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 361


>AF023476-1|AAC08702.2|  909|Homo sapiens meltrin-L precursor
           protein.
          Length = 909

 Score = 37.5 bits (83), Expect = 0.053
 Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G   G AP+  +CT  +S  I  D     L +A  +AHEL H  G+ HD
Sbjct: 313 GTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHD 361


>AL162080-1|CAB82413.1|  550|Homo sapiens hypothetical protein
           protein.
          Length = 550

 Score = 37.1 bits (82), Expect = 0.070
 Identities = 18/68 (26%), Positives = 29/68 (42%)
 Frame = +3

Query: 429 ELSNYVFTMDEQCRTEFGEGFSVCRSVRFGLRAQGCGVPTALCLTCAGSKRAPPLEGTPC 608
           +L    +  + QC+  FGE    C           C   +   L C  +K  P  +GT C
Sbjct: 59  DLPGTSYDANRQCQFTFGEDSKHCPDAASTCSTLWCTGTSGGVLVCQ-TKHFPWADGTSC 117

Query: 609 GQNQWCVD 632
           G+ +WC++
Sbjct: 118 GEGKWCIN 125


>DQ202398-1|ABA43715.1|  465|Homo sapiens ADAM21-like protein
           protein.
          Length = 465

 Score = 36.7 bits (81), Expect = 0.093
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEGLT-SAFV--IAHELAHLLGLTHDGE 253
           G A + G+C       +D  +G T S F   +AHEL H LG+ HD E
Sbjct: 138 GLAYIAGICRPPIDCGVDNFQGDTWSLFANTVAHELGHTLGMQHDEE 184


>AF029900-1|AAC52042.1|  542|Homo sapiens ADAM 21 protein.
          Length = 542

 Score = 36.7 bits (81), Expect = 0.093
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = +2

Query: 2   EKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRD 181
           E+ L   ++W    L +L       DA     ++ L    G A V G+C       +D  
Sbjct: 93  EQVLNDFSQWKQISLSQLQH-----DAAHMFIKNSLISILGLAYVAGICRPPIDCGVDNF 147

Query: 182 EGLT-SAFV--IAHELAHLLGLTHDGE 253
           +G T S F   +AHEL + LG+ HD E
Sbjct: 148 QGDTWSLFANTVAHELGYTLGMQHDEE 174


>AF171931-1|AAF03779.1|  787|Homo sapiens
           metallaproteinase-disintegrin gama protein.
          Length = 787

 Score = 35.9 bits (79), Expect = 0.16
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244
           D +   T   L G SG     G+CT  RS AI    ++  G T +  +AH L H LG+ H
Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342

Query: 245 D 247
           D
Sbjct: 343 D 343


>AF171930-1|AAF03778.1|  766|Homo sapiens
           metallaproteinase-disintegrin beta protein.
          Length = 766

 Score = 35.9 bits (79), Expect = 0.16
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244
           D +   T   L G SG     G+CT  RS AI    ++  G T +  +AH L H LG+ H
Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342

Query: 245 D 247
           D
Sbjct: 343 D 343


>AF171929-1|AAF03777.1|  820|Homo sapiens
           metallaproteinase-disintegrin protein.
          Length = 820

 Score = 35.9 bits (79), Expect = 0.16
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244
           D +   T   L G SG     G+CT  RS AI    ++  G T +  +AH L H LG+ H
Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342

Query: 245 D 247
           D
Sbjct: 343 D 343


>AF134708-1|AAF22163.1|  820|Homo sapiens disintegrin and
           metalloproteinase domain 29 protein.
          Length = 820

 Score = 35.9 bits (79), Expect = 0.16
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244
           D +   T   L G SG     G+CT  RS AI    ++  G T +  +AH L H LG+ H
Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342

Query: 245 D 247
           D
Sbjct: 343 D 343


>AC105914-1|AAY41055.1|  820|Homo sapiens unknown protein.
          Length = 820

 Score = 35.9 bits (79), Expect = 0.16
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI----DRDEGLTSAFVIAHELAHLLGLTH 244
           D +   T   L G SG     G+CT  RS AI    ++  G T +  +AH L H LG+ H
Sbjct: 284 DTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLG-TFSIAVAHHLGHNLGMNH 342

Query: 245 D 247
           D
Sbjct: 343 D 343


>BC103829-1|AAI03830.1|  276|Homo sapiens ADAMTS13 protein protein.
          Length = 276

 Score = 34.3 bits (75), Expect = 0.50
 Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228


>BC103828-1|AAI03829.1|  276|Homo sapiens ADAMTS13 protein protein.
          Length = 276

 Score = 34.3 bits (75), Expect = 0.50
 Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H
Sbjct: 173 DLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228


>AY532929-1|AAS54901.1|   90|Homo sapiens von Willebrand
           factor-cleaving protease protein.
          Length = 90

 Score = 34.3 bits (75), Expect = 0.50
 Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
 Frame = +2

Query: 77  DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 226
           D  +++TR  L  P G   V      GG C+ T S  I  D G      IAHE+ H
Sbjct: 35  DLVLYITRFDLELPDGNRQVRVVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 90


>Y13786-1|CAC20585.1|  918|Homo sapiens meltrin-beta/ADAM 19
           homologue protein.
          Length = 918

 Score = 33.9 bits (74), Expect = 0.66
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           G   G AP+  +C+  +S  ++ D    +   A  +AHE+ H  G+THD
Sbjct: 308 GTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHD 356


>AF311317-1|AAK07852.1|  918|Homo sapiens disintegrin and
           metalloproteinase ADAM19 protein.
          Length = 918

 Score = 33.9 bits (74), Expect = 0.66
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           G   G AP+  +C+  +S  ++ D    +   A  +AHE+ H  G+THD
Sbjct: 308 GTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHD 356


>AF134707-1|AAF22162.1|  857|Homo sapiens disintegrin and
           metalloproteinase domain 19 protein.
          Length = 857

 Score = 33.9 bits (74), Expect = 0.66
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHD 247
           G   G AP+  +C+  +S  ++ D    +   A  +AHE+ H  G+THD
Sbjct: 210 GTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHD 258


>D26579-1|BAA05626.1|  824|Homo sapiens transmembrane protein
           protein.
          Length = 824

 Score = 33.5 bits (73), Expect = 0.87
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHDG--EAIVSLKR 274
           G   GFA V  +C+ + S A+++D        A  +AHE+ H LG+ HD   +     +R
Sbjct: 298 GTTVGFARVSAMCSHS-SGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQER 356

Query: 275 FEA 283
           FEA
Sbjct: 357 FEA 359


>BC115404-1|AAI15405.1|  824|Homo sapiens ADAM8 protein protein.
          Length = 824

 Score = 33.5 bits (73), Expect = 0.87
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
 Frame = +2

Query: 110 GGPSGFAPVGGVCTKTRSAAIDRDEGLTS---AFVIAHELAHLLGLTHDG--EAIVSLKR 274
           G   GFA V  +C+ + S A+++D        A  +AHE+ H LG+ HD   +     +R
Sbjct: 298 GTTVGFARVSAMCSHS-SGAVNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQER 356

Query: 275 FEA 283
           FEA
Sbjct: 357 FEA 359


>BC025378-1|AAH25378.2|  776|Homo sapiens ADAM metallopeptidase
           domain 20 protein.
          Length = 776

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G A V G+C    +  +D  E    +  A  + HEL H LG+ HD
Sbjct: 359 GVAYVKGICQNPFNTGVDVFEDNRLVVFAITLGHELGHNLGMQHD 403


>AF158643-1|AAD55254.1|  726|Homo sapiens
           metalloproteinase-disintegrin protein.
          Length = 726

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G A V G+C    +  +D  E    +  A  + HEL H LG+ HD
Sbjct: 309 GVAYVKGICQNPFNTGVDVFEDNRLVVFAITLGHELGHNLGMQHD 353


>AF029899-1|AAC52041.1|  726|Homo sapiens ADAM 20 protein.
          Length = 726

 Score = 30.7 bits (66), Expect = 6.1
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
 Frame = +2

Query: 122 GFAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAHLLGLTHD 247
           G A V G+C    +  +D  E    +  A  + HEL H LG+ HD
Sbjct: 309 GVAYVKGICQNPFNTGVDVFEDNRLVVFAITLGHELGHNLGMQHD 353


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 133,779,278
Number of Sequences: 237096
Number of extensions: 3216707
Number of successful extensions: 12441
Number of sequences better than 10.0: 145
Number of HSP's better than 10.0 without gapping: 11452
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12349
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9423020542
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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