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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0078
         (739 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Y15056-1|CAA75341.1|  556|Homo sapiens PkB kinase protein.            135   1e-31
CR536517-1|CAG38755.1|  556|Homo sapiens PDPK1 protein.               135   1e-31
BC033494-1|AAH33494.1|  429|Homo sapiens 3-phosphoinositide depe...   135   1e-31
BC012103-1|AAH12103.1|  556|Homo sapiens 3-phosphoinositide depe...   135   1e-31
BC006339-1|AAH06339.2|  429|Homo sapiens 3-phosphoinositide depe...   135   1e-31
AK222581-1|BAD96301.1|  556|Homo sapiens 3-phosphoinositide depe...   135   1e-31
AF017995-1|AAC51825.1|  556|Homo sapiens 3-phosphoinositide depe...   135   1e-31
AC005591-2|AAC33798.1|  319|Homo sapiens PkB-like protein.            135   1e-31
BC146787-1|AAI46788.1| 1364|Homo sapiens pleckstrin homology dom...    33   0.81 
AK123305-1|BAC85577.1|  269|Homo sapiens protein ( Homo sapiens ...    33   0.81 
AB033026-1|BAA86514.1| 1403|Homo sapiens KIAA1200 protein protein.     33   0.81 
AL833400-1|CAD38637.1|  930|Homo sapiens hypothetical protein pr...    33   1.4  
AB095948-1|BAC23124.1| 1449|Homo sapiens KIAA2028 protein protein.     33   1.4  
CR457365-1|CAG33646.1|  201|Homo sapiens CERK protein.                 30   7.5  
BC108712-1|AAI08713.1|  201|Homo sapiens ceramide kinase protein.      30   7.5  
BC004278-1|AAH04278.1|  201|Homo sapiens ceramide kinase protein.      30   7.5  
AK026892-1|BAB15585.1|  201|Homo sapiens protein ( Homo sapiens ...    30   7.5  
AB081753-1|BAC16513.1|  985|Homo sapiens RIN3 protein.                 30   7.5  
AY515311-1|AAS87212.1|  924|Homo sapiens sONE protein.                 30   10.0 
AK096734-1|BAC04853.1|  340|Homo sapiens protein ( Homo sapiens ...    30   10.0 

>Y15056-1|CAA75341.1|  556|Homo sapiens PkB kinase protein.
          Length = 556

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 456 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 515

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 516 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 547


>CR536517-1|CAG38755.1|  556|Homo sapiens PDPK1 protein.
          Length = 556

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 456 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 515

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 516 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 547


>BC033494-1|AAH33494.1|  429|Homo sapiens 3-phosphoinositide
           dependent protein kinase-1 protein.
          Length = 429

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 329 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 388

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 389 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 420


>BC012103-1|AAH12103.1|  556|Homo sapiens 3-phosphoinositide
           dependent protein kinase-1 protein.
          Length = 556

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 456 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 515

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 516 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 547


>BC006339-1|AAH06339.2|  429|Homo sapiens 3-phosphoinositide
           dependent protein kinase-1 protein.
          Length = 429

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 329 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 388

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 389 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 420


>AK222581-1|BAD96301.1|  556|Homo sapiens 3-phosphoinositide
           dependent protein kinase-1 variant protein.
          Length = 556

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 456 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 515

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 516 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 547


>AF017995-1|AAC51825.1|  556|Homo sapiens 3-phosphoinositide
           dependent protein kinase-1 protein.
          Length = 556

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 456 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 515

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 516 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 547


>AC005591-2|AAC33798.1|  319|Homo sapiens PkB-like protein.
          Length = 319

 Score =  135 bits (327), Expect = 1e-31
 Identities = 64/92 (69%), Positives = 69/92 (75%)
 Frame = +3

Query: 6   LILKQGLVDKRKGLFPRRRMLLLTTGPRLFYVDPANMILKGEIPWSPELRVEAKNFRIFL 185
           LILK G VDKRKGLF RRR LLLT GP L+YVDP N +LKGEIPWS ELR EAKNF+ F 
Sbjct: 219 LILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFF 278

Query: 186 VHTPNRTYYLEDPDSYALEWERVIDEVRIETY 281
           VHTPNRTYYL DP   A +W R I EV  + Y
Sbjct: 279 VHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRY 310


>BC146787-1|AAI46788.1| 1364|Homo sapiens pleckstrin homology domain
           containing, family H (with MyTH4 domain) member 1
           protein.
          Length = 1364

 Score = 33.5 bits (73), Expect = 0.81
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
 Frame = +3

Query: 54  RRRMLLLTTGPRLFYVDPANMILK--GEIPWSPELR-VEAKNFRIFLVHTPNRTYYL-ED 221
           +RR  +L  G  ++Y  P+++I K  G++  +   + V  +  + F + +  +TYYL  D
Sbjct: 596 KRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTAD 655

Query: 222 PDSYALEWERVIDEV 266
             S   EW RV+  +
Sbjct: 656 SPSLLEEWIRVLQSL 670


>AK123305-1|BAC85577.1|  269|Homo sapiens protein ( Homo sapiens
           cDNA FLJ41311 fis, clone BRAMY2042760. ).
          Length = 269

 Score = 33.5 bits (73), Expect = 0.81
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
 Frame = +3

Query: 54  RRRMLLLTTGPRLFYVDPANMILK--GEIPWSPELR-VEAKNFRIFLVHTPNRTYYL-ED 221
           +RR  +L  G  ++Y  P+++I K  G++  +   + V  +  + F + +  +TYYL  D
Sbjct: 111 KRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTAD 170

Query: 222 PDSYALEWERVIDEV 266
             S   EW RV+  +
Sbjct: 171 SPSLLEEWIRVLQSL 185


>AB033026-1|BAA86514.1| 1403|Homo sapiens KIAA1200 protein protein.
          Length = 1403

 Score = 33.5 bits (73), Expect = 0.81
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
 Frame = +3

Query: 54  RRRMLLLTTGPRLFYVDPANMILK--GEIPWSPELR-VEAKNFRIFLVHTPNRTYYL-ED 221
           +RR  +L  G  ++Y  P+++I K  G++  +   + V  +  + F + +  +TYYL  D
Sbjct: 635 KRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTAD 694

Query: 222 PDSYALEWERVIDEV 266
             S   EW RV+  +
Sbjct: 695 SPSLLEEWIRVLQSL 709


>AL833400-1|CAD38637.1|  930|Homo sapiens hypothetical protein
           protein.
          Length = 930

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
 Frame = +3

Query: 3   ELILKQGLVDKRKGLFP--RRRMLLLTTGPRLFYVDPANMILK--GEIPWSPELRV-EAK 167
           E + K G + K  G     +RR  +L  G  L+Y  P+++I K  G I  S    +    
Sbjct: 139 EPLEKSGYLLKMSGKVKSWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGD 198

Query: 168 NFRIFLVHTPNRTYYL-EDPDSYALEWERVIDEV 266
           N +   + T   TYYL  D  +   EW +V+  V
Sbjct: 199 NKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNV 232


>AB095948-1|BAC23124.1| 1449|Homo sapiens KIAA2028 protein protein.
          Length = 1449

 Score = 32.7 bits (71), Expect = 1.4
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
 Frame = +3

Query: 3   ELILKQGLVDKRKGLFP--RRRMLLLTTGPRLFYVDPANMILK--GEIPWSPELRV-EAK 167
           E + K G + K  G     +RR  +L  G  L+Y  P+++I K  G I  S    +    
Sbjct: 658 EPLEKSGYLLKMSGKVKSWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGD 717

Query: 168 NFRIFLVHTPNRTYYL-EDPDSYALEWERVIDEV 266
           N +   + T   TYYL  D  +   EW +V+  V
Sbjct: 718 NKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNV 751


>CR457365-1|CAG33646.1|  201|Homo sapiens CERK protein.
          Length = 201

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +1

Query: 139 GPQNCALKPKISEYF*YIRRIVHIT*KIQILTHWNGNVSSTKCVL--KHMGA-TRLKCRR 309
           GP+ C   P +S  F +    + I   + +L+  + N  S  C+L   H G+      R 
Sbjct: 115 GPEVCTRGPDLSLSFLHTEFSIFIE-HLVLLSQSSVNCVSDVCLLPRSHDGSLVSSAARG 173

Query: 310 CRRPEQSLRRCRGPRAP 360
            RRPE S R+   PR+P
Sbjct: 174 LRRPEDSSRKAFLPRSP 190


>BC108712-1|AAI08713.1|  201|Homo sapiens ceramide kinase protein.
          Length = 201

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +1

Query: 139 GPQNCALKPKISEYF*YIRRIVHIT*KIQILTHWNGNVSSTKCVL--KHMGA-TRLKCRR 309
           GP+ C   P +S  F +    + I   + +L+  + N  S  C+L   H G+      R 
Sbjct: 115 GPEVCTRGPDLSLSFLHTEFSIFIE-HLVLLSQSSVNCVSDVCLLPRSHDGSLVSSAARG 173

Query: 310 CRRPEQSLRRCRGPRAP 360
            RRPE S R+   PR+P
Sbjct: 174 LRRPEDSSRKAFLPRSP 190


>BC004278-1|AAH04278.1|  201|Homo sapiens ceramide kinase protein.
          Length = 201

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +1

Query: 139 GPQNCALKPKISEYF*YIRRIVHIT*KIQILTHWNGNVSSTKCVL--KHMGA-TRLKCRR 309
           GP+ C   P +S  F +    + I   + +L+  + N  S  C+L   H G+      R 
Sbjct: 115 GPEVCTRGPDLSLSFLHTEFSIFIE-HLVLLSQSSVNCVSDVCLLPRSHDGSLVSSAARG 173

Query: 310 CRRPEQSLRRCRGPRAP 360
            RRPE S R+   PR+P
Sbjct: 174 LRRPEDSSRKAFLPRSP 190


>AK026892-1|BAB15585.1|  201|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ23239 fis, clone COL01248. ).
          Length = 201

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
 Frame = +1

Query: 139 GPQNCALKPKISEYF*YIRRIVHIT*KIQILTHWNGNVSSTKCVL--KHMGA-TRLKCRR 309
           GP+ C   P +S  F +    + I   + +L+  + N  S  C+L   H G+      R 
Sbjct: 115 GPEVCTRGPDLSLSFLHTEFSIFIE-HLVLLSQSSVNCVSDVCLLPRSHDGSLVSSAARG 173

Query: 310 CRRPEQSLRRCRGPRAP 360
            RRPE S R+   PR+P
Sbjct: 174 LRRPEDSSRKAFLPRSP 190


>AB081753-1|BAC16513.1|  985|Homo sapiens RIN3 protein.
          Length = 985

 Score = 30.3 bits (65), Expect = 7.5
 Identities = 15/38 (39%), Positives = 18/38 (47%)
 Frame = +3

Query: 312 PQTRAEPATLPRPSGPAFYHSTPLVECAHIGNCSLGFE 425
           PQ R +PA  PR   P F   + L   AH  NC+   E
Sbjct: 187 PQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIE 224


>AY515311-1|AAS87212.1|  924|Homo sapiens sONE protein.
          Length = 924

 Score = 29.9 bits (64), Expect = 10.0
 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
 Frame = +3

Query: 300 MPALPQTRAEPATLPRPSGPAF-YHSTP 380
           +PA P T+A+PA  P  + P++  HSTP
Sbjct: 93  IPATPPTQAQPAMTPASASPSWGSHSTP 120


>AK096734-1|BAC04853.1|  340|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39415 fis, clone PLACE6016160. ).
          Length = 340

 Score = 29.9 bits (64), Expect = 10.0
 Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
 Frame = +3

Query: 300 MPALPQTRAEPATLPRPSGPAF-YHSTP 380
           +PA P T+A+PA  P  + P++  HSTP
Sbjct: 93  IPATPPTQAQPAMTPASASPSWGSHSTP 120


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,641,654
Number of Sequences: 237096
Number of extensions: 2381693
Number of successful extensions: 5539
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5210
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5539
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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