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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= brS-0058
         (781 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC064503-1|AAH64503.1|  527|Homo sapiens G protein pathway suppr...   283   5e-76
U20285-1|AAC50906.2|  500|Homo sapiens Gps1 protein.                  282   9e-76
BC000155-1|AAH00155.3|  491|Homo sapiens G protein pathway suppr...   281   2e-75
BT009834-1|AAP88836.1|  475|Homo sapiens G protein pathway suppr...   276   8e-74
AK093283-1|BAC04120.1|  549|Homo sapiens protein ( Homo sapiens ...   172   1e-42
AB209596-1|BAD92833.1|  284|Homo sapiens G protein pathway suppr...   172   1e-42
BC105005-1|AAI05006.1|  773|Homo sapiens diacylglycerol kinase, ...    31   4.7  
AB018261-1|BAA34438.1|  742|Homo sapiens KIAA0718 protein protein.     31   4.7  
BC035315-1|AAH35315.1|  431|Homo sapiens THNSL2 protein protein.       30   8.1  
AK001778-1|BAA91904.1|  265|Homo sapiens protein ( Homo sapiens ...    30   8.1  
AC092836-2|AAX88906.1|  265|Homo sapiens unknown protein.              30   8.1  

>BC064503-1|AAH64503.1|  527|Homo sapiens G protein pathway
           suppressor 1 protein.
          Length = 527

 Score =  283 bits (694), Expect = 5e-76
 Identities = 132/214 (61%), Positives = 163/214 (76%), Gaps = 4/214 (1%)
 Frame = +2

Query: 110 FSLKKA*NPPIMFEMNTAEPMQVDIPPEDNENNETEC-YVVENPTLDLETYAASYTGFAK 286
           FSL  + +   +      EPMQ+D+ P+++  N  +  YVVENP+LDLE YAASY+G  +
Sbjct: 37  FSLSASLSACTLLYEGAVEPMQIDVDPQEDPQNAPDVNYVVENPSLDLEQYAASYSGLMR 96

Query: 287 LYRLMFVADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-GLPDIAGSQD 463
           + RL F+ADHCP+LR+EALKMA+S+V  T+NV++Y  +H+KLSEA       PD      
Sbjct: 97  IERLQFIADHCPTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESG 156

Query: 464 I--PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTS 637
           +  P LDT WVE+  KKA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++
Sbjct: 157 VEPPALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSN 216

Query: 638 ALKCYSRARDYCTSGKHLVMMCLNVVKVSVYLQN 739
           ALKCYSRARDYCTS KH++ MCLNV+KVSVYLQN
Sbjct: 217 ALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQN 250


>U20285-1|AAC50906.2|  500|Homo sapiens Gps1 protein.
          Length = 500

 Score =  282 bits (692), Expect = 9e-76
 Identities = 132/207 (63%), Positives = 162/207 (78%), Gaps = 5/207 (2%)
 Frame = +2

Query: 134 PPIMFEMNTA-EPMQVDIPPEDNENNETEC-YVVENPTLDLETYAASYTGFAKLYRLMFV 307
           P  +F +  A EPMQ+D+ P+++  N  +  YVVENP+LDLE YAASY+G  ++ RL F+
Sbjct: 17  PVQVFNLQGAVEPMQIDVDPQEDPQNAPDVNYVVENPSLDLEQYAASYSGLMRIERLQFI 76

Query: 308 ADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-GLPDIAGSQDI--PVLD 478
           ADHCP+LR+EALKMA+S+V  T+NV++Y  +H+KLSEA       PD      +  P LD
Sbjct: 77  ADHCPTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESGVEPPALD 136

Query: 479 TIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTSALKCYSR 658
           T WVE+  KKA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++ALKCYSR
Sbjct: 137 TAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSR 196

Query: 659 ARDYCTSGKHLVMMCLNVVKVSVYLQN 739
           ARDYCTS KH++ MCLNV+KVSVYLQN
Sbjct: 197 ARDYCTSAKHVINMCLNVIKVSVYLQN 223


>BC000155-1|AAH00155.3|  491|Homo sapiens G protein pathway
           suppressor 1 protein.
          Length = 491

 Score =  281 bits (690), Expect = 2e-75
 Identities = 133/211 (63%), Positives = 164/211 (77%), Gaps = 9/211 (4%)
 Frame = +2

Query: 134 PPIMFEMNTA-EPMQVDIPPEDNENNETEC-YVVENPTLDLETYAASYTGFAKLYRLMFV 307
           P  +F +  A EPMQ+D+ P+++  N  +  YVVENP+LDLE YAASY+G  ++ RL F+
Sbjct: 4   PVQVFNLQGAVEPMQIDVDPQEDPQNAPDVNYVVENPSLDLEQYAASYSGLMRIERLQFI 63

Query: 308 ADHCPSLRLEALKMAISYVMTTYNVNLYHTLHKKLSEAVASA-----GLPDIAGSQDI-- 466
           ADHCP+LR+EALKMA+S+V  T+NV++Y  +H+KLSEA  S+       PD      +  
Sbjct: 64  ADHCPTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRSSLRELQNAPDAIPESGVEP 123

Query: 467 PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTSALK 646
           P LDT WVE+  KKA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++ALK
Sbjct: 124 PALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALK 183

Query: 647 CYSRARDYCTSGKHLVMMCLNVVKVSVYLQN 739
           CYSRARDYCTS KH++ MCLNV+KVSVYLQN
Sbjct: 184 CYSRARDYCTSAKHVINMCLNVIKVSVYLQN 214


>BT009834-1|AAP88836.1|  475|Homo sapiens G protein pathway
           suppressor 1 protein.
          Length = 475

 Score =  276 bits (676), Expect = 8e-74
 Identities = 128/198 (64%), Positives = 157/198 (79%), Gaps = 8/198 (4%)
 Frame = +2

Query: 170 MQVDIPPEDNENNETEC-YVVENPTLDLETYAASYTGFAKLYRLMFVADHCPSLRLEALK 346
           MQ+D+ P+++  N  +  YVVENP+LDLE YAASY+G  ++ RL F+ADHCP+LR+EALK
Sbjct: 1   MQIDVDPQEDPQNAPDVNYVVENPSLDLEQYAASYSGLMRIERLQFIADHCPTLRVEALK 60

Query: 347 MAISYVMTTYNVNLYHTLHKKLSEAVASA-----GLPDIAGSQDI--PVLDTIWVESKTK 505
           MA+S+V  T+NV++Y  +H+KLSEA  S+       PD      +  P LDT WVE+  K
Sbjct: 61  MALSFVQRTFNVDMYEEIHRKLSEATRSSLRELQNAPDAIPESGVEPPALDTAWVEATRK 120

Query: 506 KAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTSALKCYSRARDYCTSGK 685
           KA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++ALKCYSRARDYCTS K
Sbjct: 121 KALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAK 180

Query: 686 HLVMMCLNVVKVSVYLQN 739
           H++ MCLNV+KVSVYLQN
Sbjct: 181 HVINMCLNVIKVSVYLQN 198


>AK093283-1|BAC04120.1|  549|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35964 fis, clone TESTI2012592, highly similar to
           G PROTEIN PATHWAY SUPPRESSOR 1. ).
          Length = 549

 Score =  172 bits (419), Expect = 1e-42
 Identities = 76/91 (83%), Positives = 83/91 (91%)
 Frame = +2

Query: 467 PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTSALK 646
           P LDT WVE+  KKA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++ALK
Sbjct: 109 PALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALK 168

Query: 647 CYSRARDYCTSGKHLVMMCLNVVKVSVYLQN 739
           CYSRARDYCTS KH++ MCLNV+KVSVYLQN
Sbjct: 169 CYSRARDYCTSAKHVINMCLNVIKVSVYLQN 199


>AB209596-1|BAD92833.1|  284|Homo sapiens G protein pathway
           suppressor 1 isoform 2 variant protein.
          Length = 284

 Score =  172 bits (419), Expect = 1e-42
 Identities = 76/91 (83%), Positives = 83/91 (91%)
 Frame = +2

Query: 467 PVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHDDLGDHYLDCGDLTSALK 646
           P LDT WVE+  KKA +KLEKLDTDLKNYK NSIKESIRRGHDDLGDHYLDCGDL++ALK
Sbjct: 45  PALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALK 104

Query: 647 CYSRARDYCTSGKHLVMMCLNVVKVSVYLQN 739
           CYSRARDYCTS KH++ MCLNV+KVSVYLQN
Sbjct: 105 CYSRARDYCTSAKHVINMCLNVIKVSVYLQN 135


>BC105005-1|AAI05006.1|  773|Homo sapiens diacylglycerol kinase,
           beta 90kDa protein.
          Length = 773

 Score = 31.1 bits (67), Expect = 4.7
 Identities = 22/103 (21%), Positives = 47/103 (45%)
 Frame = +2

Query: 416 EAVASAGLPDIAGSQDIPVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHD 595
           E +A   +P + G  ++      W ESK +++  ++EK  +D +   T++  + ++    
Sbjct: 657 EGIAILNIPSMHGGSNL------WGESKKRRSHRRIEKKGSDKRTTVTDA--KELKFASQ 708

Query: 596 DLGDHYLDCGDLTSALKCYSRARDYCTSGKHLVMMCLNVVKVS 724
           DL D  L+   L  A++         ++G+ L      V++ S
Sbjct: 709 DLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRTS 751


>AB018261-1|BAA34438.1|  742|Homo sapiens KIAA0718 protein protein.
          Length = 742

 Score = 31.1 bits (67), Expect = 4.7
 Identities = 22/103 (21%), Positives = 47/103 (45%)
 Frame = +2

Query: 416 EAVASAGLPDIAGSQDIPVLDTIWVESKTKKAAIKLEKLDTDLKNYKTNSIKESIRRGHD 595
           E +A   +P + G  ++      W ESK +++  ++EK  +D +   T++  + ++    
Sbjct: 595 EGIAILNIPSMHGGSNL------WGESKKRRSHRRIEKKGSDKRTTVTDA--KELKFASQ 646

Query: 596 DLGDHYLDCGDLTSALKCYSRARDYCTSGKHLVMMCLNVVKVS 724
           DL D  L+   L  A++         ++G+ L      V++ S
Sbjct: 647 DLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVIRTS 689


>BC035315-1|AAH35315.1|  431|Homo sapiens THNSL2 protein protein.
          Length = 431

 Score = 30.3 bits (65), Expect = 8.1
 Identities = 16/30 (53%), Positives = 19/30 (63%)
 Frame = +2

Query: 371 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 460
           T +VNL   LH KLSEAV S  + D A +Q
Sbjct: 294 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 323


>AK001778-1|BAA91904.1|  265|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10916 fis, clone OVARC1000309, weakly similar to
           THREONINE SYNTHASE (EC 4.2.99.2). ).
          Length = 265

 Score = 30.3 bits (65), Expect = 8.1
 Identities = 16/30 (53%), Positives = 19/30 (63%)
 Frame = +2

Query: 371 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 460
           T +VNL   LH KLSEAV S  + D A +Q
Sbjct: 128 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 157


>AC092836-2|AAX88906.1|  265|Homo sapiens unknown protein.
          Length = 265

 Score = 30.3 bits (65), Expect = 8.1
 Identities = 16/30 (53%), Positives = 19/30 (63%)
 Frame = +2

Query: 371 TYNVNLYHTLHKKLSEAVASAGLPDIAGSQ 460
           T +VNL   LH KLSEAV S  + D A +Q
Sbjct: 128 TQSVNLPKELHSKLSEAVTSVSVSDEAITQ 157


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,323,891
Number of Sequences: 237096
Number of extensions: 2175928
Number of successful extensions: 7262
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7100
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7255
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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