Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= brP-0092
(700 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209616-1|BAD92853.1| 386|Homo sapiens MAD, mothers against de... 143 5e-34
AB004930-1|BAA22032.1| 435|Homo sapiens Smad 3 protein. 143 5e-34
U76622-1|AAB18967.1| 425|Homo sapiens JV15-2 protein. 140 3e-33
U68019-1|AAB80960.1| 425|Homo sapiens mad protein homolog protein. 140 3e-33
BC050743-1|AAH50743.1| 425|Homo sapiens SMAD family member 3 pr... 140 3e-33
AF025300-1|AAL68976.1| 425|Homo sapiens Smad3 protein. 140 3e-33
U78733-1|AAC39657.1| 467|Homo sapiens Smad2 protein. 125 1e-31
U68018-1|AAB17087.1| 467|Homo sapiens mad protein homolog protein. 125 1e-31
U65019-1|AAB17054.1| 467|Homo sapiens MAD-related protein 2 pro... 125 1e-31
U59911-1|AAC50789.1| 467|Homo sapiens JV18-1 protein. 125 1e-31
BT007422-1|AAP36090.1| 467|Homo sapiens MAD, mothers against de... 125 1e-31
BC025699-1|AAH25699.1| 467|Homo sapiens SMAD family member 2 pr... 125 1e-31
BC014840-1|AAH14840.1| 467|Homo sapiens SMAD family member 2 pr... 125 1e-31
AF027964-1|AAC51918.1| 467|Homo sapiens MAD-related protein Sma... 125 1e-31
U73825-1|AAB95090.1| 465|Homo sapiens Smad5 protein. 131 3e-30
U59913-1|AAC50791.1| 465|Homo sapiens Smad5 protein. 131 3e-30
CR457424-1|CAG33705.1| 465|Homo sapiens MADH5 protein. 131 3e-30
BC009682-1|AAH09682.1| 465|Homo sapiens SMAD family member 5 pr... 131 3e-30
AF010607-1|AAB92396.1| 465|Homo sapiens SMAD5 protein. 131 3e-30
AF010601-1|AAB66353.1| 465|Homo sapiens SMAD5 protein. 131 3e-30
AF009744-1|AAB82655.1| 462|Homo sapiens Mad homolog protein. 131 3e-30
AF009678-1|AAB72180.1| 465|Homo sapiens Smad5 protein. 131 3e-30
D83761-1|BAA21129.1| 430|Homo sapiens mother against dpp (Mad) ... 129 1e-29
D83760-1|BAA21128.1| 467|Homo sapiens mother against dpp (Mad) ... 129 1e-29
BC104762-1|AAI04763.1| 467|Homo sapiens SMAD9 protein protein. 129 1e-29
BC104760-1|AAI04761.1| 467|Homo sapiens SMAD9 protein protein. 129 1e-29
BC011559-1|AAH11559.1| 430|Homo sapiens SMAD family member 9 pr... 129 1e-29
AL138706-3|CAI14007.1| 467|Homo sapiens SMAD family member 9 pr... 129 1e-29
AL138706-2|CAM19158.1| 430|Homo sapiens SMAD family member 9 pr... 129 1e-29
U59912-1|AAC50790.1| 465|Homo sapiens Smad1 protein. 126 6e-29
U59423-1|AAB06852.1| 465|Homo sapiens Smad1 protein. 126 6e-29
U57456-1|AAC50621.1| 465|Homo sapiens transforming growth facto... 126 6e-29
U54826-1|AAC50493.1| 465|Homo sapiens mad-related protein MADR1... 126 6e-29
BT007386-1|AAP36050.1| 465|Homo sapiens MAD, mothers against de... 126 6e-29
BC001878-1|AAH01878.1| 465|Homo sapiens SMAD family member 1 pr... 126 6e-29
U44378-1|AAA91041.1| 552|Homo sapiens Dpc4 protein. 97 7e-20
BC002379-1|AAH02379.1| 552|Homo sapiens SMAD family member 4 pr... 97 7e-20
AF045447-1|AAC03051.1| 552|Homo sapiens deleted in pancreatic c... 97 7e-20
AB043547-1|BAB40977.1| 436|Homo sapiens SMAD4 protein. 97 7e-20
BC012986-1|AAH12986.1| 496|Homo sapiens SMAD family member 6 pr... 55 2e-07
AF043640-1|AAC00497.1| 496|Homo sapiens Smad6 protein. 55 2e-07
AF041065-1|AAF14343.1| 496|Homo sapiens Smad6 protein protein. 55 2e-07
AF037469-1|AAC82331.1| 496|Homo sapiens Smad6 protein. 55 2e-07
AF035528-1|AAB94137.1| 496|Homo sapiens Smad6 protein. 55 2e-07
BC052569-1|AAH52569.1| 344|Homo sapiens SMAD6 protein protein. 50 1e-05
BC074819-1|AAH74819.2| 426|Homo sapiens SMAD family member 7 pr... 43 0.001
BC074818-1|AAH74818.2| 426|Homo sapiens SMAD family member 7 pr... 43 0.001
AF026559-1|AAL68977.1| 426|Homo sapiens Smad7 protein. 43 0.001
AF015261-1|AAB81354.1| 426|Homo sapiens Smad7 protein protein. 43 0.001
AF010193-1|AAB81246.1| 426|Homo sapiens MAD-related gene SMAD7 ... 43 0.001
BC114552-1|AAI14553.1| 1395|Homo sapiens G protein-coupled recep... 31 4.0
AL035427-1|CAB55683.1| 1395|Homo sapiens G protein-coupled recep... 31 4.0
AB007903-1|BAA23715.3| 1404|Homo sapiens KIAA0443 protein. 31 4.0
U59914-1|AAC50792.1| 235|Homo sapiens Smad6 protein. 30 6.9
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 30 9.1
AB209603-1|BAD92840.1| 337|Homo sapiens amyloid beta (A4) precu... 30 9.1
>AB209616-1|BAD92853.1| 386|Homo sapiens MAD, mothers against
decapentaplegic homolog 3 variant protein.
Length = 386
Score = 143 bits (347), Expect = 5e-34
Identities = 80/205 (39%), Positives = 115/205 (56%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 13 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 70
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E PP DY H P
Sbjct: 71 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEF-PPLDDYS----HSIP--- 122
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
++ + + L++ + + P GY+SEDG+ DH N ++ S
Sbjct: 123 -ENTNFPAGIELQSNIPETPP----------------PGYLSEDGETSDHQMNHSMDAGS 165
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 166 PNLSPNPMSPAHNNLDLQPVTYCEP 190
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 190 PAFWCSISYYELNQRV 205
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 207 ETFHASQPSMTVDGFTDP 224
>AB004930-1|BAA22032.1| 435|Homo sapiens Smad 3 protein.
Length = 435
Score = 143 bits (347), Expect = 5e-34
Identities = 82/205 (40%), Positives = 113/205 (55%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 52 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E PP DY H P+
Sbjct: 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEF-PPLDDYS----HSIPE-- 162
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
T A +E ++P GY+SEDG+ DH N ++ S
Sbjct: 163 ---NTNFPA-GIEP--QSNIP--EVGTWAAQAGLTPPPGYLSEDGETSDHQMNHSMDAGS 214
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 215 PNLSPNPMSPAHNNLDLQPVTYCEP 239
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 239 PAFWCSISYYELNQRV 254
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 256 ETFHASQPSMTVDGFTDP 273
>U76622-1|AAB18967.1| 425|Homo sapiens JV15-2 protein.
Length = 425
Score = 140 bits (340), Expect = 3e-33
Identities = 79/205 (38%), Positives = 114/205 (55%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 52 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E P P DY H P+
Sbjct: 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-PLDDYS----HSIPE-- 162
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
+ + + ++ + + P GY+SEDG+ DH N ++ S
Sbjct: 163 --NTNFPAGIEPQSNIPETPP----------------PGYLSEDGETSDHQMNHSMDAGS 204
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEP 229
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 229 PAFWCSISYYELNQRV 244
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 246 ETFHASQPSMTVDGFTDP 263
>U68019-1|AAB80960.1| 425|Homo sapiens mad protein homolog protein.
Length = 425
Score = 140 bits (340), Expect = 3e-33
Identities = 79/205 (38%), Positives = 114/205 (55%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 52 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E P P DY H P+
Sbjct: 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-PLDDYS----HSIPE-- 162
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
+ + + ++ + + P GY+SEDG+ DH N ++ S
Sbjct: 163 --NTNFPAGIEPQSNIPETPP----------------PGYLSEDGETSDHQMNHSMDAGS 204
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEP 229
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 229 PAFWCSISYYELNQRV 244
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 246 ETFHASQPSMTVDGFTDP 263
>BC050743-1|AAH50743.1| 425|Homo sapiens SMAD family member 3
protein.
Length = 425
Score = 140 bits (340), Expect = 3e-33
Identities = 79/205 (38%), Positives = 114/205 (55%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 52 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E P P DY H P+
Sbjct: 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-PLDDYS----HSIPE-- 162
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
+ + + ++ + + P GY+SEDG+ DH N ++ S
Sbjct: 163 --NTNFPAGIEPQSNIPETPP----------------PGYLSEDGETSDHQMNHSMDAGS 204
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEP 229
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 229 PAFWCSISYYELNQRV 244
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 246 ETFHASQPSMTVDGFTDP 263
>AF025300-1|AAL68976.1| 425|Homo sapiens Smad3 protein.
Length = 425
Score = 140 bits (340), Expect = 3e-33
Identities = 79/205 (38%), Positives = 114/205 (55%), Gaps = 7/205 (3%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+AI++QN +TKC+TIPR ++ +RKGLPHV+YCRLWRWP L S HEL+ ++ C
Sbjct: 52 EKAITTQNVNTKCITIPRSLDGRLQVS--HRKGLPHVIYCRLWRWPDLHSHHELRAMELC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E+A+ +KKDEVC+NPYHY ++++P LPP+LV R +E P P DY H P+
Sbjct: 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-PLDDYS----HSIPE-- 162
Query: 361 MQSGTGHSALYLEATLAQHVPGNXXXXXXXXXXXXXXXGYISEDGDPMDHNDNMNLTRLS 540
+ + + ++ + + P GY+SEDG+ DH N ++ S
Sbjct: 163 --NTNFPAGIEPQSNIPETPP----------------PGYLSEDGETSDHQMNHSMDAGS 204
Query: 541 P-------SPGGLXXEASPVLYHEP 594
P SP + PV Y EP
Sbjct: 205 PNLSPNPMSPAHNNLDLQPVTYCEP 229
Score = 38.7 bits (86), Expect = 0.020
Identities = 15/16 (93%), Positives = 15/16 (93%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
PAFWCSISYYELN RV
Sbjct: 229 PAFWCSISYYELNQRV 244
Score = 35.1 bits (77), Expect = 0.24
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 246 ETFHASQPSMTVDGFTDP 263
>U78733-1|AAC39657.1| 467|Homo sapiens Smad2 protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>U68018-1|AAB17087.1| 467|Homo sapiens mad protein homolog protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>U65019-1|AAB17054.1| 467|Homo sapiens MAD-related protein 2
protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>U59911-1|AAC50789.1| 467|Homo sapiens JV18-1 protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>BT007422-1|AAP36090.1| 467|Homo sapiens MAD, mothers against
decapentaplegic homolog 2 (Drosophila) protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>BC025699-1|AAH25699.1| 467|Homo sapiens SMAD family member 2
protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>BC014840-1|AAH14840.1| 467|Homo sapiens SMAD family member 2
protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>AF027964-1|AAC51918.1| 467|Homo sapiens MAD-related protein Smad2
protein.
Length = 467
Score = 125 bits (302), Expect(2) = 1e-31
Identities = 73/178 (41%), Positives = 95/178 (53%), Gaps = 9/178 (5%)
Frame = +1
Query: 88 YRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPPI 267
+RKGLPHV+YCRLWRWP L S HELK +++CEYA+ LKKDEVC+NPYHY ++++P LPP+
Sbjct: 119 HRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPV 178
Query: 268 LVRRCSEGEVRAPPPYADYHQPILHEHPD-VAMQSGTGHSALYLEATLAQHVPGNXXXXX 444
LV R +E + PP DY H P+ +G + Y+ T
Sbjct: 179 LVPRHTE-ILTELPPLDDY----THSIPENTNFPAGIEPQSNYIPET------------- 220
Query: 445 XXXXXXXXXXGYISEDGDPMDHNDNMNL-----TRLSP---SPGGLXXEASPVLYHEP 594
GYISEDG+ D N ++ LSP SP + PV Y EP
Sbjct: 221 -------PPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEP 271
Score = 37.9 bits (84), Expect = 0.034
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
+ PAFWCSI+YYELN RV
Sbjct: 269 SEPAFWCSIAYYELNQRV 286
Score = 35.5 bits (78), Expect = 0.18
Identities = 14/18 (77%), Positives = 15/18 (83%)
Frame = +3
Query: 645 ETFHAXXPFITVDGFTDP 698
ETFHA P +TVDGFTDP
Sbjct: 288 ETFHASQPSLTVDGFTDP 305
Score = 31.1 bits (67), Expect(2) = 1e-31
Identities = 12/17 (70%), Positives = 16/17 (94%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIP 51
E+AI++QN +TKCVTIP
Sbjct: 62 EKAITTQNCNTKCVTIP 78
>U73825-1|AAB95090.1| 465|Homo sapiens Smad5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>U59913-1|AAC50791.1| 465|Homo sapiens Smad5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>CR457424-1|CAG33705.1| 465|Homo sapiens MADH5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>BC009682-1|AAH09682.1| 465|Homo sapiens SMAD family member 5
protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>AF010607-1|AAB92396.1| 465|Homo sapiens SMAD5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>AF010601-1|AAB66353.1| 465|Homo sapiens SMAD5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>AF009744-1|AAB82655.1| 462|Homo sapiens Mad homolog protein.
Length = 462
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 50 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 107
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 108 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 143
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 265 PKHWCSIVYYELNNRV 280
>AF009678-1|AAB72180.1| 465|Homo sapiens Smad5 protein.
Length = 465
Score = 131 bits (316), Expect = 3e-30
Identities = 55/96 (57%), Positives = 72/96 (75%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+SS +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP+D C
Sbjct: 53 EKALSSPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLDIC 110
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R +E
Sbjct: 111 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNE 146
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>D83761-1|BAA21129.1| 430|Homo sapiens mother against dpp (Mad)
related protein protein.
Length = 430
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 229 CYEEPQHWCSVAYYELNNRV 248
>D83760-1|BAA21128.1| 467|Homo sapiens mother against dpp (Mad)
related protein protein.
Length = 467
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 266 CYEEPQHWCSVAYYELNNRV 285
>BC104762-1|AAI04763.1| 467|Homo sapiens SMAD9 protein protein.
Length = 467
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 266 CYEEPQHWCSVAYYELNNRV 285
>BC104760-1|AAI04761.1| 467|Homo sapiens SMAD9 protein protein.
Length = 467
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 266 CYEEPQHWCSVAYYELNNRV 285
>BC011559-1|AAH11559.1| 430|Homo sapiens SMAD family member 9
protein.
Length = 430
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 229 CYEEPQHWCSVAYYELNNRV 248
>AL138706-3|CAI14007.1| 467|Homo sapiens SMAD family member 9
protein.
Length = 467
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 266 CYEEPQHWCSVAYYELNNRV 285
>AL138706-2|CAM19158.1| 430|Homo sapiens SMAD family member 9
protein.
Length = 430
Score = 129 bits (311), Expect = 1e-29
Identities = 58/117 (49%), Positives = 77/117 (65%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA+S +KCVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 56 ERALSCPGQPSKCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHP 351
E+ + K+ EVCINPYHY ++++P LPP+LV R SE + A + LH P
Sbjct: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQL-SLLAKFRSASLHSEP 169
Score = 35.1 bits (77), Expect = 0.24
Identities = 12/20 (60%), Positives = 14/20 (70%)
Frame = +2
Query: 581 CTTSPAFWCSISYYELNTRV 640
C P WCS++YYELN RV
Sbjct: 229 CYEEPQHWCSVAYYELNNRV 248
>U59912-1|AAC50790.1| 465|Homo sapiens Smad1 protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>U59423-1|AAB06852.1| 465|Homo sapiens Smad1 protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>U57456-1|AAC50621.1| 465|Homo sapiens transforming growth
factor-beta signaling protein-1 protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>U54826-1|AAC50493.1| 465|Homo sapiens mad-related protein MADR1
protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>BT007386-1|AAP36050.1| 465|Homo sapiens MAD, mothers against
decapentaplegic homolog 1 (Drosophila) protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>BC001878-1|AAH01878.1| 465|Homo sapiens SMAD family member 1
protein.
Length = 465
Score = 126 bits (305), Expect = 6e-29
Identities = 53/96 (55%), Positives = 70/96 (72%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
E+A+S + CVTIPR ++ +RKGLPHV+YCR+WRWP LQS HELKP++ C
Sbjct: 52 EKALSCPGQPSNCVTIPRSLDGRLQVS--HRKGLPHVIYCRVWRWPDLQSHHELKPLECC 109
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSE 288
E+ + K+ EVCINPYHY +++SP LPP+LV R SE
Sbjct: 110 EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSE 145
Score = 31.9 bits (69), Expect = 2.3
Identities = 12/16 (75%), Positives = 12/16 (75%)
Frame = +2
Query: 593 PAFWCSISYYELNTRV 640
P WCSI YYELN RV
Sbjct: 268 PKHWCSIVYYELNNRV 283
>U44378-1|AAA91041.1| 552|Homo sapiens Dpc4 protein.
Length = 552
Score = 96.7 bits (230), Expect = 7e-20
Identities = 43/85 (50%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Frame = +1
Query: 7 AISSQNSH-TKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCE 183
AI++ +H +KCVTI R + G RKG PHV+Y RLWRWP L ++ELK V +C+
Sbjct: 60 AITTNGAHPSKCVTIQRTLDGRLQVAG--RKGFPHVIYARLWRWPDLH-KNELKHVKYCQ 116
Query: 184 YAYQLKKDEVCINPYHYNKIDSPAL 258
YA+ LK D VC+NPYHY ++ SP +
Sbjct: 117 YAFDLKCDSVCVNPYHYERVVSPGI 141
>BC002379-1|AAH02379.1| 552|Homo sapiens SMAD family member 4
protein.
Length = 552
Score = 96.7 bits (230), Expect = 7e-20
Identities = 43/85 (50%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Frame = +1
Query: 7 AISSQNSH-TKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCE 183
AI++ +H +KCVTI R + G RKG PHV+Y RLWRWP L ++ELK V +C+
Sbjct: 60 AITTNGAHPSKCVTIQRTLDGRLQVAG--RKGFPHVIYARLWRWPDLH-KNELKHVKYCQ 116
Query: 184 YAYQLKKDEVCINPYHYNKIDSPAL 258
YA+ LK D VC+NPYHY ++ SP +
Sbjct: 117 YAFDLKCDSVCVNPYHYERVVSPGI 141
>AF045447-1|AAC03051.1| 552|Homo sapiens deleted in pancreatic
carcinoma protein.
Length = 552
Score = 96.7 bits (230), Expect = 7e-20
Identities = 43/85 (50%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Frame = +1
Query: 7 AISSQNSH-TKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCE 183
AI++ +H +KCVTI R + G RKG PHV+Y RLWRWP L ++ELK V +C+
Sbjct: 60 AITTNGAHPSKCVTIQRTLDGRLQVAG--RKGFPHVIYARLWRWPDLH-KNELKHVKYCQ 116
Query: 184 YAYQLKKDEVCINPYHYNKIDSPAL 258
YA+ LK D VC+NPYHY ++ SP +
Sbjct: 117 YAFDLKCDSVCVNPYHYERVVSPGI 141
>AB043547-1|BAB40977.1| 436|Homo sapiens SMAD4 protein.
Length = 436
Score = 96.7 bits (230), Expect = 7e-20
Identities = 43/85 (50%), Positives = 58/85 (68%), Gaps = 1/85 (1%)
Frame = +1
Query: 7 AISSQNSH-TKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCE 183
AI++ +H +KCVTI R + G RKG PHV+Y RLWRWP L ++ELK V +C+
Sbjct: 60 AITTNGAHPSKCVTIQRTLDGRLQVAG--RKGFPHVIYARLWRWPDLH-KNELKHVKYCQ 116
Query: 184 YAYQLKKDEVCINPYHYNKIDSPAL 258
YA+ LK D VC+NPYHY ++ SP +
Sbjct: 117 YAFDLKCDSVCVNPYHYERVVSPGI 141
>BC012986-1|AAH12986.1| 496|Homo sapiens SMAD family member 6
protein.
Length = 496
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYAD 321
C NPYH++++ P PP R S + P +D
Sbjct: 260 CCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSD 295
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 326 TKPSHWCSVAYWEHRTRV 343
>AF043640-1|AAC00497.1| 496|Homo sapiens Smad6 protein.
Length = 496
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYAD 321
C NPYH++++ P PP R S + P +D
Sbjct: 260 CCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSD 295
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 326 TKPSHWCSVAYWEHRTRV 343
>AF041065-1|AAF14343.1| 496|Homo sapiens Smad6 protein protein.
Length = 496
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYAD 321
C NPYH++++ P PP R S + P +D
Sbjct: 260 CCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSD 295
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 326 TKPSHWCSVAYWEHRTRV 343
>AF037469-1|AAC82331.1| 496|Homo sapiens Smad6 protein.
Length = 496
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYAD 321
C NPYH++++ P PP R S + P +D
Sbjct: 260 CCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSD 295
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 326 TKPSHWCSVAYWEHRTRV 343
>AF035528-1|AAB94137.1| 496|Homo sapiens Smad6 protein.
Length = 496
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYAD 321
C NPYH++++ P PP R S + P +D
Sbjct: 260 CCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSD 295
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 326 TKPSHWCSVAYWEHRTRV 343
>BC052569-1|AAH52569.1| 344|Homo sapiens SMAD6 protein protein.
Length = 344
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 37 CVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC-EYAYQLKKDEV 213
CV +PR + + GQ P ++ RL+RWP LQ ELKP+ C +A V
Sbjct: 205 CVLVPRA---DLRLGGQ--PAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTV 259
Query: 214 CINPYHYNKIDSP 252
C NPYH++++ P
Sbjct: 260 CCNPYHFSRLCGP 272
>BC074819-1|AAH74819.2| 426|Homo sapiens SMAD family member 7
protein.
Length = 426
Score = 42.7 bits (96), Expect = 0.001
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = +1
Query: 109 VVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPP 264
++ C+++RWP L+ E+K + CE ++ + VC NP+H +++ PP
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP 208
>BC074818-1|AAH74818.2| 426|Homo sapiens SMAD family member 7
protein.
Length = 426
Score = 42.7 bits (96), Expect = 0.001
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = +1
Query: 109 VVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPP 264
++ C+++RWP L+ E+K + CE ++ + VC NP+H +++ PP
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP 208
>AF026559-1|AAL68977.1| 426|Homo sapiens Smad7 protein.
Length = 426
Score = 42.7 bits (96), Expect = 0.001
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = +1
Query: 109 VVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPP 264
++ C+++RWP L+ E+K + CE ++ + VC NP+H +++ PP
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP 208
>AF015261-1|AAB81354.1| 426|Homo sapiens Smad7 protein protein.
Length = 426
Score = 42.7 bits (96), Expect = 0.001
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = +1
Query: 109 VVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPP 264
++ C+++RWP L+ E+K + CE ++ + VC NP+H +++ PP
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP 208
>AF010193-1|AAB81246.1| 426|Homo sapiens MAD-related gene SMAD7
protein.
Length = 426
Score = 42.7 bits (96), Expect = 0.001
Identities = 16/52 (30%), Positives = 31/52 (59%)
Frame = +1
Query: 109 VVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKIDSPALPP 264
++ C+++RWP L+ E+K + CE ++ + VC NP+H +++ PP
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP 208
>BC114552-1|AAI14553.1| 1395|Homo sapiens G protein-coupled receptor
associated sorting protein 1 protein.
Length = 1395
Score = 31.1 bits (67), Expect = 4.0
Identities = 22/107 (20%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Frame = +1
Query: 67 ESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKID 246
E+GI + R G W W + Q+ + + C+ +++E I + + +++
Sbjct: 563 EAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVE 622
Query: 247 SPALPPILVRRCSEGEVRAPPPYADYHQ---PILHEHPDVAMQSGTG 378
+ C EG+V + D + P +V+M+ GTG
Sbjct: 623 A----------CVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTG 659
>AL035427-1|CAB55683.1| 1395|Homo sapiens G protein-coupled receptor
associated sorting protein 1 protein.
Length = 1395
Score = 31.1 bits (67), Expect = 4.0
Identities = 22/107 (20%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Frame = +1
Query: 67 ESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKID 246
E+GI + R G W W + Q+ + + C+ +++E I + + +++
Sbjct: 563 EAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVE 622
Query: 247 SPALPPILVRRCSEGEVRAPPPYADYHQ---PILHEHPDVAMQSGTG 378
+ C EG+V + D + P +V+M+ GTG
Sbjct: 623 A----------CVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTG 659
>AB007903-1|BAA23715.3| 1404|Homo sapiens KIAA0443 protein.
Length = 1404
Score = 31.1 bits (67), Expect = 4.0
Identities = 22/107 (20%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Frame = +1
Query: 67 ESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEVCINPYHYNKID 246
E+GI + R G W W + Q+ + + C+ +++E I + + +++
Sbjct: 572 EAGIGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVE 631
Query: 247 SPALPPILVRRCSEGEVRAPPPYADYHQ---PILHEHPDVAMQSGTG 378
+ C EG+V + D + P +V+M+ GTG
Sbjct: 632 A----------CVEGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTG 668
>U59914-1|AAC50792.1| 235|Homo sapiens Smad6 protein.
Length = 235
Score = 30.3 bits (65), Expect = 6.9
Identities = 10/18 (55%), Positives = 14/18 (77%)
Frame = +2
Query: 587 TSPAFWCSISYYELNTRV 640
T P+ WCS++Y+E TRV
Sbjct: 65 TKPSHWCSVAYWEHRTRV 82
>DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short form
variant 2 protein.
Length = 1178
Score = 29.9 bits (64), Expect = 9.1
Identities = 27/125 (21%), Positives = 47/125 (37%)
Frame = +1
Query: 1 ERAISSQNSHTKCVTIPRVKPNESGINGQYRKGLPHVVYCRLWRWPQLQSQHELKPVDHC 180
ERA Q H+ I + N ++ GLP V ++W + + + D
Sbjct: 21 ERAKHDQQFHS-LKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM---DQV 76
Query: 181 EYAYQLKKDEVCINPYHYNKIDSPALPPILVRRCSEGEVRAPPPYADYHQPILHEHPDVA 360
E++ +K ++ + Y P + V S A PP A+ P++ P A
Sbjct: 77 EFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPPFAAVPPLANGAPPVIQPLPAFA 136
Query: 361 MQSGT 375
+ T
Sbjct: 137 HPAAT 141
>AB209603-1|BAD92840.1| 337|Homo sapiens amyloid beta (A4)
precursor protein-binding, family A, member 3 variant
protein.
Length = 337
Score = 29.9 bits (64), Expect = 9.1
Identities = 15/36 (41%), Positives = 16/36 (44%)
Frame = -2
Query: 465 SLHC*GAHVYSCVARHVLCKCSLEIQCAVSCTRLHG 358
S C H+ S AR C C I C C RLHG
Sbjct: 277 SRRCQLPHIASLQARSSPCTCDHLIPCLPLCLRLHG 312
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.316 0.135 0.426
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,058,217
Number of Sequences: 237096
Number of extensions: 2330494
Number of successful extensions: 5795
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 5340
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5756
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
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