KWMTBOMO12013

Protein

Length

1,561 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
246 - 499
Endonuclease/exonuclease/phosphatase (IPR005135)
1,128 - 1,371
Reverse transcriptase domain (IPR000477)

1 200 400 600 800 1000 1200 1400 1561

Detailed signature matches

IPR005135

Endonuclease/exonuclease/phosphatase
1. PF14529 (Exo_endo_p...)
  
  353 - 488
  
  Pfam
  PF14529 (Exo_endo_phos_2)
2. G3DSA:3.60.10.10
  
  252 - 492
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
3. SSF56219 (DNase I-like)
  
  246 - 499
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,162 - 1,349
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,128 - 1,371
  
  PROSITE profiles
  PS50878 (RT_POL)

no IPR

Unintegrated signatures

Coil

1 - 28

COILS
Coil (Coil)
SSF56672 (DNA/RNA p...)

1,165 - 1,343

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01650 (RT_nLTR_like)

1,159 - 1,371

CDD
cd01650 (RT_nLTR_like)
cd09076 (L1-EN)

257 - 492

CDD
cd09076 (L1-EN)
mobidb-lite (disord...)

144 - 180

MobiDB Lite
mobidb-lite (disorder_prediction)

1,127 - 1,160

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative catalytic...

261N

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

290E

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

358Y

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

392D

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

394N

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

461D

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

484D

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)

485H

putative catalytic site
261N, 290E, 358Y, 392D, 394N, 461D, 484D, 485H
CDD
cd09076 (L1-EN)
putative metal bin...

290E

putative metal binding site
290E, 484D
CDD
cd09076 (L1-EN)

484D

putative metal binding site
290E, 484D
CDD
cd09076 (L1-EN)
putative phosphate...

358Y

putative phosphate binding site
358Y, 394N, 485H
CDD
cd09076 (L1-EN)

394N

putative phosphate binding site
358Y, 394N, 485H
CDD
cd09076 (L1-EN)

485H

putative phosphate binding site
358Y, 394N, 485H
CDD
cd09076 (L1-EN)
putative NTP bindi...

1,206D

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,207Y

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,208Q

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,209K

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,210A

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,211F

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,264Q

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)

1,305D

putative NTP binding site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,305D
CDD
cd01650 (RT_nLTR_like)
putative active si...

1,206D

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,207Y

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,208Q

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,209K

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,210A

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,211F

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,264Q

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,265G

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,303F

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,305D

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,306D

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,367L

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)

1,368G

putative active site
1,206D, 1,207Y, 1,208Q, 1,209K, 1,210A, 1,211F, 1,264Q, 1,265G, 1,303F, 1,305D, 1,306D, 1,367L, 1,368G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

1,265G

putative nucleic acid binding site
1,265G
CDD
cd01650 (RT_nLTR_like)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO12013

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component