KWMTBOMO11834

Protein

Length

434 amino acids

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)

Domains and repeats

Domain
1 - 418
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 434

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  3 - 423
  
  Pfam
  PF00083 (Sugar_tr)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 412
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  1 - 404
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  2 - 153
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  207 - 418
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

2 - 142

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

275 - 413

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

10G

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

13V

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

14N

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

17A

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

21T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

22P

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

24C

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

25T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

71A

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

72A

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

75P

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

78T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

79I

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

82S

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

94T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

95S

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

98I

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

99S

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

105L

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

241L

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

244V

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

245V

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

248Q

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

249V

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

252E

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

264P

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

268T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

272A

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

275F

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

279S

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

327M

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

330F

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

331S

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

334Y

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

338P

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

344V

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

347A

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

358C

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

359N

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

362I

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

363N

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

366T

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

367W

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

370N

putative substrate translocation pore
10G, 13V, 14N, 17A, 21T, 22P, 24C, 25T, 71A, 72A, 75P, 78T, 79I, 82S, 94T, 95S, 98I, 99S, 105L, 241L, 244V, 245V, 248Q, 249V, 252E, 264P, 268T, 272A, 275F, 279S, 327M, 330F, 331S, 334Y, 338P, 344V, 347A, 358C, 359N, 362I, 363N, 366T, 367W, 370N
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features