KWMTBOMO11662

Protein

Length

234 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 229
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 234

Detailed signature matches

IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  5 - 221
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  1 - 229
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
IPR020904

Short-chain dehydrogenase/reductase, conserved site
1. PS00061 (ADH_SHORT)
  
  129 - 157
  
  PROSITE patterns
  PS00061 (ADH_SHORT)

no IPR

Unintegrated signatures

PF13561 (adh_short_C2)

43 - 185

Pfam
PF13561 (adh_short_C2)
cd05334 (DHPR_SDR_c...)

4 - 224

CDD
cd05334 (DHPR_SDR_c_like)

Residue annotation

NAD binding site c...

9Y

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

10G

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

12R

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

13G

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

14A

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

15L

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

34D

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

47V

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

56Q

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

79V

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

80A

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

81G

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

82G

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

102Q

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

106S

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

127T

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

128G

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

142Y

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

146K

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

174P

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

175V

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

176T

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

177L

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

179T

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)

182N

NAD binding site
9Y, 10G, 12R, 13G, 14A, 15L, 34D, 47V, 56Q, 79V, 80A, 81G, 82G, 102Q, 106S, 127T, 128G, 142Y, 146K, 174P, 175V, 176T, 177L, 179T, 182N
CDD
cd05334 (DHPR_SDR_c_like)
homodimer interfac...

57E

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

86G

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

87N

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

88A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

89A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

92L

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

93S

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

94K

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

96A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

97D

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

108S

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

112T

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

115A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

132A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

134E

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

135A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

136T

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

137P

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

140I

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

143G

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

144M

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

148A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

151Q

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

152L

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

154K

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

155S

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

156L

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

158A

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

159K

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

160D

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

161S

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)

162G

homodimer interface
57E, 86G, 87N, 88A, 89A, 92L, 93S, 94K, 96A, 97D, 108S, 112T, 115A, 132A, 134E, 135A, 136T, 137P, 140I, 143G, 144M, 148A, 151Q, 152L, 154K, 155S, 156L, 158A, 159K, 160D, 161S, 162G
CDD
cd05334 (DHPR_SDR_c_like)
active site cd05334

142Y

active site
142Y, 146K
CDD
cd05334 (DHPR_SDR_c_like)

146K

active site
142Y, 146K
CDD
cd05334 (DHPR_SDR_c_like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO11662

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component