KWMTBOMO11497

Protein

Length

513 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
57 - 498
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 513

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  119 - 449
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  57 - 493
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  113 - 486
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  117 - 498
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

308 - 506

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

118 - 273

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

122S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

125Q

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

126T

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

129P

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

133A

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

134L

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

136I

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

137G

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

191G

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

192G

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

197T

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

198M

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

201Y

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

202S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

205S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

217I

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

218G

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

221T

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

222A

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

228K

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

320V

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

323L

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

324L

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

327A

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

328Q

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

331M

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

345Y

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

349L

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

353V

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

356G

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

360S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

409D

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

412S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

413S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

416A

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

420R

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

421S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

424S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

435T

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

436S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

439I

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

440S

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

443E

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

444A

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

447P

putative substrate translocation pore
122S, 125Q, 126T, 129P, 133A, 134L, 136I, 137G, 191G, 192G, 197T, 198M, 201Y, 202S, 205S, 217I, 218G, 221T, 222A, 228K, 320V, 323L, 324L, 327A, 328Q, 331M, 345Y, 349L, 353V, 356G, 360S, 409D, 412S, 413S, 416A, 420R, 421S, 424S, 435T, 436S, 439I, 440S, 443E, 444A, 447P
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO11497

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component