KWMTBOMO11256

Protein

Length

234 amino acids

Protein family membership

Peptidase C15, pyroglutamyl peptidase I-like (IPR016125)
- Peptidase C15, pyroglutamyl peptidase I (IPR000816)

Domains and repeats

None predicted.

Detailed signature matches

IPR016125

Peptidase C15, pyroglutamyl peptidase I-like
1. G3DSA:3.40.63...
  
  13 - 208
  
  GENE3D
  G3DSA:3.40.630.20 (G3DSA:3.40.630.20)
2. PF01470 (Peptidase_C15)
  
  13 - 190
  
  Pfam
  PF01470 (Peptidase_C15)
IPR000816

Peptidase C15, pyroglutamyl peptidase I
1. PR00706 (PYROGLUPTASE)
  
  74 - 86
  
  PRINTS
  PR00706 (PYROGLUPTASE)
  
  147 - 163
  
  PRINTS
  PR00706 (PYROGLUPTASE)
  
  13 - 36
  
  PRINTS
  PR00706 (PYROGLUPTASE)
2. PIRSF015592 (Pyrrol...)
  
  10 - 215
  
  PIRSF
  PIRSF015592 (Pyrrolidone-crbxlat_pptds)
3. cd00501 (Peptidase_C15)
  
  12 - 210
  
  CDD
  cd00501 (Peptidase_C15)

no IPR

Unintegrated signatures

SSF53182 (Pyrrolido...)

12 - 206

SUPERFAMILY
SSF53182 (Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase))

Residue annotation

putative substrate...

18F

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)

21F

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)

56V

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)

156Y

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)

157L

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)

158C

putative substrate binding pocket
18F, 21F, 56V, 156Y, 157L, 158C
CDD
cd00501 (Peptidase_C15)
AC domain interfac...

86A

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

87N

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

88E

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

137N

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

140S

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

141P

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

142E

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

147A

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

148V

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

186S

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

187E

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

189T

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

195R

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

196I

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)

198E

AC domain interface
86A, 87N, 88E, 137N, 140S, 141P, 142E, 147A, 148V, 186S, 187E, 189T, 195R, 196I, 198E
CDD
cd00501 (Peptidase_C15)
catalytic triad cd...

92E

catalytic triad
92E, 158C, 177H
CDD
cd00501 (Peptidase_C15)

158C

catalytic triad
92E, 158C, 177H
CDD
cd00501 (Peptidase_C15)

177H

catalytic triad
92E, 158C, 177H
CDD
cd00501 (Peptidase_C15)
AB domain interfac...

93V

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

94Q

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

98K

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

100Y

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

102R

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

112N

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

113H

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

121V

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

122R

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

123I

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

124H

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

130E

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

151K

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

152D

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)

155R

AB domain interface
93V, 94Q, 98K, 100Y, 102R, 112N, 113H, 121V, 122R, 123I, 124H, 130E, 151K, 152D, 155R
CDD
cd00501 (Peptidase_C15)
interchain disulfi...

198E

interchain disulfide
198E
CDD
cd00501 (Peptidase_C15)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0016920 pyroglutamyl-peptidase activity

Cellular Component

GO:0005829 cytosol

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO11256

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component