KWMTBOMO11058

Protein

Length

909 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
38 - 128
BRCT domain (IPR001357)
281 - 518
UmuC domain (IPR001126)
573 - 696
DNA polymerase, Y-family, little finger domain (IPR017961)
818 - 906
DNA repair protein Rev1, C-terminal (IPR031991)

1 100 200 300 400 500 600 700 800 909

Detailed signature matches

IPR001357

BRCT domain
1. SM00292 (BRCT_7)
  
  44 - 117
  
  SMART
  SM00292 (BRCT_7)
2. G3DSA:3.40.50...
  
  38 - 123
  
  GENE3D
  G3DSA:3.40.50.10190 (G3DSA:3.40.50.10190)
3. PS50172 (BRCT)
  
  42 - 127
  
  PROSITE profiles
  PS50172 (BRCT)
4. PF16589 (BRCT_2)
  
  44 - 126
  
  Pfam
  PF16589 (BRCT_2)
5. SSF52113 (BRCT domain)
  
  40 - 128
  
  SUPERFAMILY
  SSF52113 (BRCT domain)
6. cd00027 (BRCT)
  
  49 - 115
  
  CDD
  cd00027 (BRCT)
IPR001126

UmuC domain
1. PF00817 (IMS)
  
  284 - 487
  
  Pfam
  PF00817 (IMS)
2. PS50173 (UMUC)
  
  281 - 518
  
  PROSITE profiles
  PS50173 (UMUC)
IPR017961

DNA polymerase, Y-family, little finger domain
1. SSF100879 (Lesion b...)
  
  573 - 687
  
  SUPERFAMILY
  SSF100879 (Lesion bypass DNA polymerase (Y-family), little finger domain)
2. G3DSA:3.30.14...
  
  575 - 690
  
  GENE3D
  G3DSA:3.30.1490.100 (G3DSA:3.30.1490.100)
3. PF11799 (IMS_C)
  
  573 - 696
  
  Pfam
  PF11799 (IMS_C)
IPR031991

DNA repair protein Rev1, C-terminal
1. PF16727 (REV1_C)
  
  818 - 906
  
  Pfam
  PF16727 (REV1_C)

no IPR

Unintegrated signatures

Coil

727 - 747

COILS
Coil (Coil)
G3DSA:1.10.15...

501 - 565

GENE3D
G3DSA:1.10.150.20 (G3DSA:1.10.150.20)
G3DSA:3.30.70...

398 - 496

GENE3D
G3DSA:3.30.70.270 (G3DSA:3.30.70.270)
SSF56672 (DNA/RNA p...)

369 - 565

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)

277 - 309

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01701 (PolY_Rev1)

218 - 689

CDD
cd01701 (PolY_Rev1)
mobidb-lite (disord...)

733 - 799

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Dimer interface cd...

63D

Dimer interface
63D, 67C, 70S, 73G, 75V
CDD
cd00027 (BRCT)

67C

Dimer interface
63D, 67C, 70S, 73G, 75V
CDD
cd00027 (BRCT)

70S

Dimer interface
63D, 67C, 70S, 73G, 75V
CDD
cd00027 (BRCT)

73G

Dimer interface
63D, 67C, 70S, 73G, 75V
CDD
cd00027 (BRCT)

75V

Dimer interface
63D, 67C, 70S, 73G, 75V
CDD
cd00027 (BRCT)
BRCT sequence moti...

109W

BRCT sequence motif
109W, 113S
CDD
cd00027 (BRCT)

113S

BRCT sequence motif
109W, 113S
CDD
cd00027 (BRCT)
DNA binding site c...

221E

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

222F

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

223Y

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

225N

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

226S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

227R

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

228L

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

229H

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

231I

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

232S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

239K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

285D

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

286M

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

287D

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

288C

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

289F

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

290F

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

310H

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

374A

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

375S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

378Y

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

381R

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

387N

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

388G

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

390F

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

432V

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

433S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

435D

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

436E

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

490K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

514L

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

515P

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

516G

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

517V

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

518G

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

519R

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

520Q

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

521I

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

524K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

550T

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

551K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

575K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

576S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

577V

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

578S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

579A

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

580E

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

581V

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

582N

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

583Y

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

617C

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

638G

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

639H

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

640G

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

644V

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

645I

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

646N

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

647K

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

648S

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)

650N

DNA binding site
221E, 222F, 223Y, 225N, 226S, 227R, 228L, 229H, 231I, 232S, 239K, 285D, 286M, 287D, 288C, 289F, 290F, 310H, 374A, 375S, 378Y, 381R, 387N, 388G, 390F, 432V, 433S, 435D, 436E, 490K, 514L, 515P, 516G, 517V, 518G, 519R, 520Q, 521I, 524K, 550T, 551K, 575K, 576S, 577V, 578S, 579A, 580E, 581V, 582N, 583Y, 617C, 638G, 639H, 640G, 644V, 645I, 646N, 647K, 648S, 650N
CDD
cd01701 (PolY_Rev1)
active site cd01701

227R

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

285D

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

286M

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

287D

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

288C

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

289F

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

290F

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

374A

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

375S

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

378Y

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

381R

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

387N

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

435D

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

436E

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

490K

active site
227R, 285D, 286M, 287D, 288C, 289F, 290F, 374A, 375S, 378Y, 381R, 387N, 435D, 436E, 490K
CDD
cd01701 (PolY_Rev1)

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003684 damaged DNA binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO11058

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component