KWMTBOMO10964

Protein

Length

565 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
9 - 54
CRIB domain (IPR000095)
p21 activated kinase binding domain (IPR033923)
298 - 560
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 100 200 300 400 500 565

Detailed signature matches

IPR000095

CRIB domain
1. G3DSA:3.90.81...
  
  10 - 50
  
  GENE3D
  G3DSA:3.90.810.10 (G3DSA:3.90.810.10)
2. SM00285 (PBD_5)
  
  11 - 46
  
  SMART
  SM00285 (PBD_5)
3. PS50108 (CRIB)
  
  11 - 24
  
  PROSITE profiles
  PS50108 (CRIB)
4. PF00786 (PBD)
  
  11 - 48
  
  Pfam
  PF00786 (PBD)
IPR033923

p21 activated kinase binding domain
1. cd01093 (CRIB_PAK_like)
  
  9 - 54
  
  CDD
  cd01093 (CRIB_PAK_like)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  302 - 560
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  298 - 549
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. PF00069 (Pkinase)
  
  302 - 549
  
  Pfam
  PF00069 (Pkinase)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  304 - 327
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

361 - 552

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

292 - 360

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd06648 (STKc_PAK_II)

290 - 550

CDD
cd06648 (STKc_PAK_II)
mobidb-lite (disord...)

96 - 159

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

GTPase interaction...

11I

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

14P

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

17F

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

19H

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

22H

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

39W

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)

43V

GTPase interaction site
11I, 14P, 17F, 19H, 22H, 39W, 43V
CDD
cd01093 (CRIB_PAK_like)
ATP binding site c...

304I

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

305G

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

306K

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

307G

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

308S

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

312V

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

325A

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

327K

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

356V

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

372M

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

373E

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

374Y

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

375M

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

376A

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

378G

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

379A

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

382D

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

421D

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

422S

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

424L

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

434S

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)

435D

ATP binding site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 421D, 422S, 424L, 434S, 435D
CDD
cd06648 (STKc_PAK_II)
active site cd06648

304I

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

305G

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

306K

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

307G

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

308S

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

312V

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

325A

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

327K

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

356V

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

372M

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

373E

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

374Y

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

375M

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

376A

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

378G

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

379A

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

382D

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

417D

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

419K

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

420S

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

421D

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

422S

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

424L

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

434S

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

435D

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

438F

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

451S

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

452L

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

453V

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

454G

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

455T

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

457Y

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

484E

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

493F

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

494N

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

495E

active site
304I, 305G, 306K, 307G, 308S, 312V, 325A, 327K, 356V, 372M, 373E, 374Y, 375M, 376A, 378G, 379A, 382D, 417D, 419K, 420S, 421D, 422S, 424L, 434S, 435D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)
polypeptide substr...

307G

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

308S

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

336R

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

417D

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

419K

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

420S

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

421D

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

438F

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

451S

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

452L

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

453V

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

454G

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

455T

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

457Y

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

484E

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

493F

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

494N

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)

495E

polypeptide substrate binding site
307G, 308S, 336R, 417D, 419K, 420S, 421D, 438F, 451S, 452L, 453V, 454G, 455T, 457Y, 484E, 493F, 494N, 495E
CDD
cd06648 (STKc_PAK_II)
activation loop (A...

434S

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

435D

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

436F

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

437G

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

438F

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

439C

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

440A

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

441Q

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

442V

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

443S

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

444Q

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

445E

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

446L

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

447P

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

448K

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

449R

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

450K

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

451S

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

452L

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

453V

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

454G

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

455T

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

456P

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

457Y

activation loop (A-loop)
434S, 435D, 436F, 437G, 438F, 439C, 440A, 441Q, 442V, 443S, 444Q, 445E, 446L, 447P, 448K, 449R, 450K, 451S, 452L, 453V, 454G, 455T, 456P, 457Y
CDD
cd06648 (STKc_PAK_II)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component