KWMTBOMO10849

Protein

Length

549 amino acids

Protein family membership

YjgF/YER057c/UK114 family (IPR006175)

Domains and repeats

Domain
1 - 154
Rossmann-like alpha/beta/alpha sandwich fold (IPR014729)
Domain
1 - 226
Diphthamide synthase domain (IPR002761)
360 - 454
Endoribonuclease L-PSP/chorismate mutase-like (IPR013813)
470 - 548
Endoribonuclease L-PSP/chorismate mutase-like (IPR013813)

1 50 100 150 200 250 300 350 400 450 500 549

Detailed signature matches

IPR006175

YjgF/YER057c/UK114 family
1. PF01042 (Ribonuc_L-PSP)
  
  481 - 537
  
  Pfam
  PF01042 (Ribonuc_L-PSP)
  
  376 - 438
  
  Pfam
  PF01042 (Ribonuc_L-PSP)
IPR014729

Rossmann-like alpha/beta/alpha sandwich fold
1. G3DSA:3.40.50...
  
  1 - 154
  
  GENE3D
  G3DSA:3.40.50.620 (G3DSA:3.40.50.620)
IPR002761

Diphthamide synthase domain
1. TIGR00290
  
  1 - 226
  
  TIGRFAMs
  TIGR00290 (TIGR00290)
2. PF01902 (Diphthami_...)
  
  1 - 226
  
  Pfam
  PF01902 (Diphthami_syn_2)
3. cd01994 (Alpha_ANH_...)
  
  2 - 211
  
  CDD
  cd01994 (Alpha_ANH_like_IV)
IPR013813

Endoribonuclease L-PSP/chorismate mutase-like
1. SSF55298 (YjgF-like)
  
  360 - 441
  
  SUPERFAMILY
  SSF55298 (YjgF-like)
  
  470 - 537
  
  SUPERFAMILY
  SSF55298 (YjgF-like)
2. G3DSA:3.30.13...
  
  472 - 548
  
  GENE3D
  G3DSA:3.30.1330.40 (G3DSA:3.30.1330.40)
  
  364 - 454
  
  GENE3D
  G3DSA:3.30.1330.40 (G3DSA:3.30.1330.40)

no IPR

Unintegrated signatures

G3DSA:3.90.14...

156 - 248

GENE3D
G3DSA:3.90.1490.10 (G3DSA:3.90.1490.10)
SSF52402 (Adenine n...)

1 - 240

SUPERFAMILY
SSF52402 (Adenine nucleotide alpha hydrolases-like)
cd06155 (eu_AANH_C_1)

358 - 452

CDD
cd06155 (eu_AANH_C_1)

Residue annotation

Ligand Binding Sit...

6L

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

7I

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

8S

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

10G

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

11K

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

12D

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

13S

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

31A

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)

33L

Ligand Binding Site
6L, 7I, 8S, 10G, 11K, 12D, 13S, 31A, 33L
CDD
cd01994 (Alpha_ANH_like_IV)
homotrimer interac...

359K

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

361G

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

362W

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

364F

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

366G

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

367G

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

399D

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

401C

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

402S

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

404N

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

406Y

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

417N

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

420Y

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

424F

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

429P

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

430P

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

431T

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

432R

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

433V

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

434C

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

435V

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

436Q

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

437C

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

446I

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

448D

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)

450V

homotrimer interaction site
359K, 361G, 362W, 364F, 366G, 367G, 399D, 401C, 402S, 404N, 406Y, 417N, 420Y, 424F, 429P, 430P, 431T, 432R, 433V, 434C, 435V, 436Q, 437C, 446I, 448D, 450V
CDD
cd06155 (eu_AANH_C_1)
putative active si...

413Y

putative active site
413Y, 417N, 432R, 446I
CDD
cd06155 (eu_AANH_C_1)

417N

putative active site
413Y, 417N, 432R, 446I
CDD
cd06155 (eu_AANH_C_1)

432R

putative active site
413Y, 417N, 432R, 446I
CDD
cd06155 (eu_AANH_C_1)

446I

putative active site
413Y, 417N, 432R, 446I
CDD
cd06155 (eu_AANH_C_1)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO10849

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component