KWMTBOMO10502

Protein

Length

444 amino acids

Protein family membership

Fumarate lyase family (IPR000362)
- Adenylosuccinate lyase (IPR004769)

Domains and repeats

Domain
7 - 66
Fumarase/histidase, N-terminal (IPR024083)
63 - 262
Fumarate lyase, N-terminal (IPR022761)
334 - 418
Adenylosuccinate lyase C-terminal (IPR019468)
Domain
8 - 419
L-Aspartase-like (IPR008948)

1 50 100 150 200 250 300 350 400 444

Detailed signature matches

IPR000362

Fumarate lyase family
1. PR00149 (FUMRATELYASE)
  
  108 - 126
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  202 - 229
  
  PRINTS
  PR00149 (FUMRATELYASE)
  
  245 - 261
  
  PRINTS
  PR00149 (FUMRATELYASE)
IPR004769

Adenylosuccinate lyase
1. TIGR00928
  
  8 - 417
  
  TIGRFAMs
  TIGR00928 (TIGR00928)
IPR024083

Fumarase/histidase, N-terminal
1. G3DSA:1.10.27...
  
  7 - 66
  
  GENE3D
  G3DSA:1.10.275.10 (G3DSA:1.10.275.10)
IPR008948

L-Aspartase-like
1. SSF48557 (L-asparta...)
  
  8 - 419
  
  SUPERFAMILY
  SSF48557 (L-aspartase-like)
IPR022761

Fumarate lyase, N-terminal
1. PF00206 (Lyase_1)
  
  63 - 262
  
  Pfam
  PF00206 (Lyase_1)
IPR019468

Adenylosuccinate lyase C-terminal
1. PF10397 (ADSL_C)
  
  335 - 417
  
  Pfam
  PF10397 (ADSL_C)
2. SM00998 (ADSL_C_2)
  
  334 - 418
  
  SMART
  SM00998 (ADSL_C_2)
IPR020557

Fumarate lyase, conserved site
1. PS00163 (FUMARATE_L...)
  
  245 - 254
  
  PROSITE patterns
  PS00163 (FUMARATE_LYASES)

no IPR

Unintegrated signatures

G3DSA:1.20.20...

67 - 415

GENE3D
G3DSA:1.20.200.10 (G3DSA:1.20.200.10)
PR00145 (ARGSUCLYASE)

202 - 226

PRINTS
PR00145 (ARGSUCLYASE)

245 - 261

PRINTS
PR00145 (ARGSUCLYASE)

103 - 123

PRINTS
PR00145 (ARGSUCLYASE)
cd03302 (Adenylsucc...)

8 - 409

CDD
cd03302 (Adenylsuccinate_lyase_2)

Residue annotation

active site cd03302

43H

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

64H

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

116H

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

198Q

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

252K

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

254N

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)

259E

active site
43H, 64H, 116H, 198Q, 252K, 254N, 259E
CDD
cd03302 (Adenylsuccinate_lyase_2)
tetramer interface...

44D

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

53G

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

62I

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

63I

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

65L

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

66G

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

114F

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

115T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

116H

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

117L

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

118Q

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

119P

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

121Q

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

127K

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

128R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

131L

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

134N

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

135D

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

141R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

142A

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

158T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

159T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

160G

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

161T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

164S

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

193Y

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

195V

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

196T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

203K

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

207E

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

214G

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

221K

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

225D

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

227R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

228I

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

230A

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

231S

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

253R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

254N

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

259E

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

263A

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

266R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

267H

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

269I

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

270T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

273A

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

274N

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

277N

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

278T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

282Q

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

283W

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

284L

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

285E

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

286R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

287T

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

288L

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

292A

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

293N

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

295R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

300E

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

340E

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

344M

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

347V

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

353R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

354Q

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

407I

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

409R

tetramer interface
44D, 53G, 62I, 63I, 65L, 66G, 114F, 115T, 116H, 117L, 118Q, 119P, 121Q, 127K, 128R, 131L, 134N, 135D, 141R, 142A, 158T, 159T, 160G, 161T, 164S, 193Y, 195V, 196T, 203K, 207E, 214G, 221K, 225D, 227R, 228I, 230A, 231S, 253R, 254N, 259E, 263A, 266R, 267H, 269I, 270T, 273A, 274N, 277N, 278T, 282Q, 283W, 284L, 285E, 286R, 287T, 288L, 292A, 293N, 295R, 300E, 340E, 344M, 347V, 353R, 354Q, 407I, 409R
CDD
cd03302 (Adenylsuccinate_lyase_2)

GO term prediction

Biological Process

GO:0009152 purine ribonucleotide biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features