KWMTBOMO10277

Protein

Length

472 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
1 - 442
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 472

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  6 - 401
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  1 - 442
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  58 - 429
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  3 - 28
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  57 - 438
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

241 - 443

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

4 - 223

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

69L

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

72F

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

73Y

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

76Y

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

80H

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

81L

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

83G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

84G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

133E

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

134G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

137F

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

138P

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

141N

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

142A

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

145A

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

157G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

158S

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

161F

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

162G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

168N

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

262D

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

265Y

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

266F

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

269V

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

270T

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

273P

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

287T

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

291A

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

295Y

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

298M

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

302S

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

359S

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

362L

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

363M

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

366F

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

370M

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

371K

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

374A

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

385I

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

386M

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

389V

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

390N

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

393G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

394A

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

397G

putative substrate translocation pore
69L, 72F, 73Y, 76Y, 80H, 81L, 83G, 84G, 133E, 134G, 137F, 138P, 141N, 142A, 145A, 157G, 158S, 161F, 162G, 168N, 262D, 265Y, 266F, 269V, 270T, 273P, 287T, 291A, 295Y, 298M, 302S, 359S, 362L, 363M, 366F, 370M, 371K, 374A, 385I, 386M, 389V, 390N, 393G, 394A, 397G
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO10277

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component