Protein

KWMTBOMO10169

Length
473 amino acids

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 473

Detailed signature matches

  1. Family IPR023031
    Orotate phosphoribosyltransferase
    1. MF_01208 (PyrE)
  2. Family IPR014732
    Orotidine 5'-phosphate decarboxylase
    1. TIGR01740
  3. Domain IPR029057
    Phosphoribosyltransferase-like
    1. SSF53271 (PRTase-like)
    2. G3DSA:3.40.50...
  4. Domain IPR000836
    Phosphoribosyltransferase domain
    1. cd06223 (PRTases_typeI)
    2. PF00156 (Pribosyltran)
  5. Domain IPR004467
    Orotate phosphoribosyl transferase domain
    1. TIGR00336
  6. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  7. Domain IPR011060
    Ribulose-phosphate binding barrel
    1. SSF51366 (Ribulose-...)
  8. Domain IPR001754
    Orotidine 5'-phosphate decarboxylase domain
    1. PF00215 (OMPdecase)
    2. SM00934 (OMPdecase_2)
  9. SITE IPR018089
    Orotidine 5'-phosphate decarboxylase, active site
    1. PS00156 (OMPDECASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd04725 (OMP_decarb...)

Residue annotation

  1. active site cd06223
  2. active site cd04725
  3. dimer interface cd...

GO term prediction

Biological Process

GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0008152 metabolic process
GO:0009116 nucleoside metabolic process
GO:0044205 'de novo' UMP biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004588 orotate phosphoribosyltransferase activity
GO:0004590 orotidine-5'-phosphate decarboxylase activity

Cellular Component

None predicted.