KWMTBOMO10057

Protein

Length

273 amino acids

Protein family membership

Inositol monophosphatase-like (IPR000760)
- Inositol monophosphatase, Lithium-sensitive (IPR020552)
- Inositol monophosphatase (IPR033942)

Domains and repeats

None predicted.

Detailed signature matches

IPR000760

Inositol monophosphatase-like
1. PF00459 (Inositol_P)
  
  6 - 264
  
  Pfam
  PF00459 (Inositol_P)
2. PR00377 (IMPHPHTASES)
  
  41 - 61
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  184 - 205
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  215 - 239
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  63 - 79
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  136 - 159
  
  PRINTS
  PR00377 (IMPHPHTASES)
  
  87 - 103
  
  PRINTS
  PR00377 (IMPHPHTASES)
IPR033942

Inositol monophosphatase
1. cd01639 (IMPase)
  
  8 - 253
  
  CDD
  cd01639 (IMPase)
IPR020552

Inositol monophosphatase, Lithium-sensitive
1. PR00378 (LIIMPHPHTASE)
  
  161 - 171
  
  PRINTS
  PR00378 (LIIMPHPHTASE)
  
  110 - 120
  
  PRINTS
  PR00378 (LIIMPHPHTASE)
  
  19 - 38
  
  PRINTS
  PR00378 (LIIMPHPHTASE)
  
  243 - 265
  
  PRINTS
  PR00378 (LIIMPHPHTASE)
  
  138 - 156
  
  PRINTS
  PR00378 (LIIMPHPHTASE)
IPR020583

Inositol monophosphatase, metal-binding site
1. PS00629 (IMP_1)
  
  87 - 100
  
  PROSITE patterns
  PS00629 (IMP_1)
IPR020550

Inositol monophosphatase, conserved site
1. PS00630 (IMP_2)
  
  218 - 232
  
  PROSITE patterns
  PS00630 (IMP_2)

no IPR

Unintegrated signatures

G3DSA:3.30.54...

5 - 154

GENE3D
G3DSA:3.30.540.10 (G3DSA:3.30.540.10)
G3DSA:3.40.19...

155 - 267

GENE3D
G3DSA:3.40.190.80 (G3DSA:3.40.190.80)
SSF56655 (Carbohydr...)

6 - 269

SUPERFAMILY
SSF56655 (Carbohydrate phosphatase)

Residue annotation

active site cd01639

36K

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

41D

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

47D

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

70E

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

71E

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

90D

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

91P

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

92V

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

93D

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

94G

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

95T

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

218W

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)

219D

active site
36K, 41D, 47D, 70E, 71E, 90D, 91P, 92V, 93D, 94G, 95T, 218W, 219D
CDD
cd01639 (IMPase)
dimerization inter...

40I

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

42L

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

96M

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

97N

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

99V

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

100H

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

101G

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

102F

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

103P

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

104H

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

156T

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

157A

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

158L

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

160T

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

162E

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

163A

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

172F

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

173K

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

176M

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

179Y

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

182L

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

187H

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

188G

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

189V

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

190R

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

191T

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

192L

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

193G

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

201M

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

205G

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

206G

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

207A

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

208D

dimerization interface
40I, 42L, 96M, 97N, 99V, 100H, 101G, 102F, 103P, 104H, 156T, 157A, 158L, 160T, 162E, 163A, 172F, 173K, 176M, 179Y, 182L, 187H, 188G, 189V, 190R, 191T, 192L, 193G, 201M, 205G, 206G, 207A, 208D
CDD
cd01639 (IMPase)

GO term prediction

Biological Process

GO:0046854 phosphatidylinositol phosphorylation
GO:0046855 inositol phosphate dephosphorylation

Molecular Function

GO:0008934 inositol monophosphate 1-phosphatase activity

Cellular Component