KWMTBOMO09941

Protein

Length

508 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
13 - 469
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 508

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  106 - 427
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  18 - 469
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  108 - 463
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  13 - 53
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  102 - 465
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

102 - 249

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

14 - 53

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

282 - 470

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

109F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

110M

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

113F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

117G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

118V

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

120L

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

121G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

167E

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

168S

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

171N

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

172P

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

175T

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

176G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

179T

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

191L

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

192S

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

195N

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

196W

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

202Y

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

296H

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

299G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

300M

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

303A

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

304Y

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

307D

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

320G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

324F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

328V

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

331G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

335V

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

389F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

392E

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

395F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

399F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

400A

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

403V

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

414T

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

415V

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

418F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

420F

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

423N

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

424N

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

427G

putative substrate translocation pore
109F, 110M, 113F, 117G, 118V, 120L, 121G, 167E, 168S, 171N, 172P, 175T, 176G, 179T, 191L, 192S, 195N, 196W, 202Y, 296H, 299G, 300M, 303A, 304Y, 307D, 320G, 324F, 328V, 331G, 335V, 389F, 392E, 395F, 399F, 400A, 403V, 414T, 415V, 418F, 420F, 423N, 424N, 427G
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO09941

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component