Protein

KWMTBOMO09597

Length
926 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 926

Detailed signature matches

  1. Family IPR011407
    10-formyltetrahydrofolate dehydrogenase
    1. PIRSF036489 (10-FTHFDH)
  2. Domain IPR002376
    Formyl transferase, N-terminal
    1. G3DSA:3.40.50...
    2. SSF53328 (Formyltra...)
    3. PF00551 (Formyl_tra...)
  3. Domain IPR011034
    Formyl transferase, C-terminal-like
    1. SSF50486 (FMT C-ter...)
  4. Domain IPR005793
    Formyl transferase, C-terminal
    1. PF02911 (Formyl_tra...)
    2. G3DSA:3.10.25.10
  5. Domain IPR009081
    Phosphopantetheine binding ACP domain
    1. G3DSA:1.10.12...
    2. PS50075 (ACP_DOMAIN)
    3. PF00550 (PP-binding)
    4. SSF47336 (ACP-like)
  6. Domain IPR016161
    Aldehyde/histidinol dehydrogenase
    1. SSF53720 (ALDH-like)
  7. Domain IPR016162
    Aldehyde dehydrogenase N-terminal domain
    1. G3DSA:3.40.60...
  8. Domain IPR015590
    Aldehyde dehydrogenase domain
    1. PF00171 (Aldedh)
  9. Domain IPR016163
    Aldehyde dehydrogenase, C-terminal
    1. G3DSA:3.40.30...
  10. SITE IPR029510
    Aldehyde dehydrogenase, glutamic acid active site
    1. PS00687 (ALDEHYDE_D...)
  11. SITE IPR016160
    Aldehyde dehydrogenase, cysteine active site
    1. PS00070 (ALDEHYDE_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07140 (ALDH_F1L_F...)

Residue annotation

  1. homotetrameric int...
  2. NADP binding site ...
  3. catalytic residues...

GO term prediction

Biological Process

GO:0006730 one-carbon metabolic process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0009258 10-formyltetrahydrofolate catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0016155 formyltetrahydrofolate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016742 hydroxymethyl-, formyl- and related transferase activity

Cellular Component

GO:0005737 cytoplasm