KWMTBOMO09592

Protein

Length

372 amino acids

Protein family membership

Asparaginase/glutaminase (IPR006034)

Domains and repeats

Domain
4 - 223
L-asparaginase, N-terminal (IPR027474)
239 - 366
L-asparaginase, C-terminal domain (IPR027473)

1 50 100 150 200 250 300 372

Detailed signature matches

IPR006034

Asparaginase/glutaminase
1. PS51732 (ASN_GLN_ASE_3)
  
  5 - 360
  
  PROSITE profiles
  PS51732 (ASN_GLN_ASE_3)
2. SM00870 (Asparagina...)
  
  6 - 353
  
  SMART
  SM00870 (Asparaginase_2)
3. PIRSF001220 (L-ASNa...)
  
  54 - 365
  
  PIRSF
  PIRSF001220 (L-ASNase_gatD)
4. SSF53774 (Glutamina...)
  
  4 - 365
  
  SUPERFAMILY
  SSF53774 (Glutaminase/Asparaginase)
5. PR00139 (ASNGLNASE)
  
  109 - 127
  
  PRINTS
  PR00139 (ASNGLNASE)
  
  7 - 18
  
  PRINTS
  PR00139 (ASNGLNASE)
  
  289 - 307
  
  PRINTS
  PR00139 (ASNGLNASE)
IPR027474

L-asparaginase, N-terminal
1. PF00710 (Asparaginase)
  
  6 - 217
  
  Pfam
  PF00710 (Asparaginase)
2. G3DSA:3.40.50...
  
  4 - 223
  
  GENE3D
  G3DSA:3.40.50.1170 (G3DSA:3.40.50.1170)
IPR027473

L-asparaginase, C-terminal domain
1. G3DSA:3.40.50.40
  
  239 - 366
  
  GENE3D
  G3DSA:3.40.50.40 (G3DSA:3.40.50.40)

no IPR

Unintegrated signatures

PIRSF500176 (L_ASNase)

67 - 363

PIRSF
PIRSF500176 (L_ASNase)
SFLDS00057 (Glutami...)

3 - 368

SFLD
SFLDS00057 (Glutaminase/Asparaginase)
cd08963 (L-asparagi...)

5 - 346

CDD
cd08963 (L-asparaginase_I)

Residue annotation

active site cd08963

14G

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

15T

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

86S

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

87S

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

116G

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

117T

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

118D

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

143A

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)

189K

active site
14G, 15T, 86S, 87S, 116G, 117T, 118D, 143A, 189K
CDD
cd08963 (L-asparaginase_I)
SFLDS00057

15T

SFLD_Res01
15T, 141T
SFLD
SFLDS00057 (Glutaminase/Asparaginase)

141T

SFLD_Res01
15T, 141T
SFLD
SFLDS00057 (Glutaminase/Asparaginase)
homodimer interfac...

15T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

24G

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

26L

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

27V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

82E

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

85D

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

86S

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

87S

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

88D

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

89F

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

90T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

91I

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

93D

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

94W

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

118D

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

119T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

122Y

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

144Q

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

145V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

189K

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

190V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

191S

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

192N

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

193T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

194R

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

240K

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

241V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

242Y

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

243I

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

244L

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

245K

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

246V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

247A

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

248P

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

249T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

250I

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

252P

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

253E

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

256R

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

259C

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

260E

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

268E

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

270Y

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

271G

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

272N

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

276P

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

301Q

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

304N

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

305G

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

306T

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

307V

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

308L

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

313Y

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

332A

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

336W

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

340C

homodimer interface
15T, 24G, 26L, 27V, 82E, 85D, 86S, 87S, 88D, 89F, 90T, 91I, 93D, 94W, 118D, 119T, 122Y, 144Q, 145V, 189K, 190V, 191S, 192N, 193T, 194R, 240K, 241V, 242Y, 243I, 244L, 245K, 246V, 247A, 248P, 249T, 250I, 252P, 253E, 256R, 259C, 260E, 268E, 270Y, 271G, 272N, 276P, 301Q, 304N, 305G, 306T, 307V, 308L, 313Y, 332A, 336W, 340C
CDD
cd08963 (L-asparaginase_I)

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO09592

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component