KWMTBOMO09315

Protein

Length

2,834 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
1 - 94
Diacylglycerol kinase, catalytic domain (IPR001206)
863 - 1,012
Diacylglycerol kinase, accessory domain (IPR000756)
1,688 - 1,843
Ribonuclease H-like domain (IPR012337)
Integrase, catalytic core (IPR001584)
2,442 - 2,567
Diacylglycerol kinase, accessory domain (IPR000756)
2,769 - 2,834
Sterile alpha motif/pointed domain (IPR013761)
Sterile alpha motif domain (IPR001660)
Domain
13 - 88
NAD kinase/diacylglycerol kinase-like domain (IPR016064)
1,012 - 1,194
Reverse transcriptase domain (IPR000477)
2,455 - 2,586
NAD kinase/diacylglycerol kinase-like domain (IPR016064)

1 500 1000 1500 2000 2500 2834

Detailed signature matches

IPR001206

Diacylglycerol kinase, catalytic domain
1. PS50146 (DAGK)
  
  1 - 94
  
  PROSITE profiles
  PS50146 (DAGK)
2. PF00781 (DAGK_cat)
  
  13 - 73
  
  Pfam
  PF00781 (DAGK_cat)
3. SM00046 (dagk_c4a_7)
  
  1 - 86
  
  SMART
  SM00046 (dagk_c4a_7)
IPR016064

NAD kinase/diacylglycerol kinase-like domain
1. SSF111331 (NAD kina...)
  
  13 - 88
  
  SUPERFAMILY
  SSF111331 (NAD kinase/diacylglycerol kinase-like)
  
  2,455 - 2,586
  
  SUPERFAMILY
  SSF111331 (NAD kinase/diacylglycerol kinase-like)
IPR000756

Diacylglycerol kinase, accessory domain
1. SM00045 (dagk_c4b_2)
  
  2,442 - 2,567
  
  SMART
  SM00045 (dagk_c4b_2)
  
  863 - 1,012
  
  SMART
  SM00045 (dagk_c4b_2)
2. PF00609 (DAGK_acc)
  
  863 - 928
  
  Pfam
  PF00609 (DAGK_acc)
  
  2,463 - 2,566
  
  Pfam
  PF00609 (DAGK_acc)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,032 - 1,194
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,012 - 1,194
  
  PROSITE profiles
  PS50878 (RT_POL)
IPR012337

Ribonuclease H-like domain
1. G3DSA:3.30.42...
  
  1,692 - 1,842
  
  GENE3D
  G3DSA:3.30.420.10 (G3DSA:3.30.420.10)
2. SSF53098 (Ribonucle...)
  
  1,690 - 1,843
  
  SUPERFAMILY
  SSF53098 (Ribonuclease H-like)
IPR001584

Integrase, catalytic core
1. PS50994 (INTEGRASE)
  
  1,688 - 1,841
  
  PROSITE profiles
  PS50994 (INTEGRASE)
2. PF00665 (rve)
  
  1,691 - 1,795
  
  Pfam
  PF00665 (rve)
IPR013761

Sterile alpha motif/pointed domain
1. SSF47769 (SAM/Point...)
  
  2,769 - 2,834
  
  SUPERFAMILY
  SSF47769 (SAM/Pointed domain)
2. G3DSA:1.10.15...
  
  2,770 - 2,834
  
  GENE3D
  G3DSA:1.10.150.50 (G3DSA:1.10.150.50)
IPR001660

Sterile alpha motif domain
1. PF00536 (SAM_1)
  
  2,772 - 2,833
  
  Pfam
  PF00536 (SAM_1)
2. SM00454 (SAM_4)
  
  2,770 - 2,834
  
  SMART
  SM00454 (SAM_4)
3. PS50105 (SAM_DOMAIN)
  
  2,773 - 2,834
  
  PROSITE profiles
  PS50105 (SAM_DOMAIN)

no IPR

Unintegrated signatures

Coil

65 - 85

COILS
Coil (Coil)
G3DSA:3.10.10.10

986 - 1,130

GENE3D
G3DSA:3.10.10.10 (G3DSA:3.10.10.10)
SSF56672 (DNA/RNA p...)

956 - 1,392

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01647 (RT_LTR)

1,015 - 1,192

CDD
cd01647 (RT_LTR)
cd09274 (RNase_HI_R...)

1,288 - 1,407

CDD
cd09274 (RNase_HI_RT_Ty3)
mobidb-lite (disord...)

335 - 354

MobiDB Lite
mobidb-lite (disorder_prediction)

718 - 745

MobiDB Lite
mobidb-lite (disorder_prediction)

187 - 207

MobiDB Lite
mobidb-lite (disorder_prediction)

1,441 - 1,512

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative NTP bindi...

1,083D

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,084L

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,085A

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,086S

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,087G

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,088Y

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,117F

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)

1,145D

putative NTP binding site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,145D
CDD
cd01647 (RT_LTR)
putative active si...

1,083D

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,084L

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,085A

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,086S

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,087G

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,088Y

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,117F

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,118G

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,143Y

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,145D

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,146D

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,190L

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)

1,191G

putative active site
1,083D, 1,084L, 1,085A, 1,086S, 1,087G, 1,088Y, 1,117F, 1,118G, 1,143Y, 1,145D, 1,146D, 1,190L, 1,191G
CDD
cd01647 (RT_LTR)
putative nucleic a...

1,118G

putative nucleic acid binding site
1,118G
CDD
cd01647 (RT_LTR)
RNA/DNA hybrid bin...

1,292D

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,293A

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,294S

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,295D

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,328S

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,329T

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,330I

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,333E

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,358D

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,391Y

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

1,407R

RNA/DNA hybrid binding site
1,292D, 1,293A, 1,294S, 1,295D, 1,328S, 1,329T, 1,330I, 1,333E, 1,358D, 1,391Y, 1,407R
CDD
cd09274 (RNase_HI_RT_Ty3)

GO term prediction

Biological Process

GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding
GO:0004143 diacylglycerol kinase activity
GO:0005515 protein binding
GO:0016301 kinase activity

Cellular Component