KWMTBOMO09224

Protein

Length

494 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)
- Tetracycline resistance protein TetA/multidrug resistance protein MdtG (IPR001958)

Domains and repeats

Domain
2 - 401
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 494

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  8 - 318
  
  Pfam
  PF07690 (MFS_1)
IPR001958

Tetracycline resistance protein TetA/multidrug resistance protein MdtG
1. PR01035 (TCRTETA)
  
  345 - 368
  
  PRINTS
  PR01035 (TCRTETA)
  
  38 - 57
  
  PRINTS
  PR01035 (TCRTETA)
  
  162 - 182
  
  PRINTS
  PR01035 (TCRTETA)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  2 - 401
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  3 - 395
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  3 - 396
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

205 - 395

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

3 - 188

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

17V

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

20Q

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

21A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

22P

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

24Y

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

25P

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

42F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

45F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

46E

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

49V

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

53S

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

54P

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

56Y

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

57G

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

110N

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

111A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

114L

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

115T

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

118F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

119A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

122A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

133F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

134A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

137E

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

138T

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

144L

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

217T

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

220S

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

221I

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

224L

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

225Q

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

228L

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

242L

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

246F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

250G

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

253Y

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

257A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

312G

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

315I

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

316G

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

325D

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

329T

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

330S

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

333S

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

345V

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

346S

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

349W

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

350T

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

353F

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

354A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

357A

putative substrate translocation pore
17V, 20Q, 21A, 22P, 24Y, 25P, 42F, 45F, 46E, 49V, 53S, 54P, 56Y, 57G, 110N, 111A, 114L, 115T, 118F, 119A, 122A, 133F, 134A, 137E, 138T, 144L, 217T, 220S, 221I, 224L, 225Q, 228L, 242L, 246F, 250G, 253Y, 257A, 312G, 315I, 316G, 325D, 329T, 330S, 333S, 345V, 346S, 349W, 350T, 353F, 354A, 357A
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features