KWMTBOMO09085

Protein

Length

595 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
65 - 138
CRIB domain (IPR000095)
p21 activated kinase binding domain (IPR033923)
311 - 575
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 100 200 300 400 500 595

Detailed signature matches

IPR000095

CRIB domain
1. SM00285 (PBD_5)
  
  69 - 104
  
  SMART
  SM00285 (PBD_5)
2. G3DSA:3.90.81...
  
  65 - 138
  
  GENE3D
  G3DSA:3.90.810.10 (G3DSA:3.90.810.10)
3. PS50108 (CRIB)
  
  69 - 82
  
  PROSITE profiles
  PS50108 (CRIB)
4. PF00786 (PBD)
  
  69 - 125
  
  Pfam
  PF00786 (PBD)
IPR033923

p21 activated kinase binding domain
1. cd01093 (CRIB_PAK_like)
  
  67 - 112
  
  CDD
  cd01093 (CRIB_PAK_like)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  311 - 575
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. SM00220 (serkin_6)
  
  321 - 572
  
  SMART
  SM00220 (serkin_6)
2. PS50011 (PROTEIN_KI...)
  
  321 - 572
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
3. PF00069 (Pkinase)
  
  321 - 572
  
  Pfam
  PF00069 (Pkinase)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  327 - 350
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  436 - 448
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

384 - 576

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

295 - 383

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd06647 (STKc_PAK_I)

313 - 573

CDD
cd06647 (STKc_PAK_I)
mobidb-lite (disord...)

1 - 71

MobiDB Lite
mobidb-lite (disorder_prediction)

130 - 246

MobiDB Lite
mobidb-lite (disorder_prediction)

269 - 300

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

GTPase interaction...

69I

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

72P

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

75F

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

77H

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

80H

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

97W

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)

101L

GTPase interaction site
69I, 72P, 75F, 77H, 80H, 97W, 101L
CDD
cd01093 (CRIB_PAK_like)
ATP binding site c...

327I

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

328G

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

329Q

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

330G

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

331A

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

335V

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

348A

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

350K

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

379V

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

395M

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

396E

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

397Y

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

398L

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

399A

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

401G

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

402S

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

405D

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

444D

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

445N

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

447L

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

457T

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)

458D

ATP binding site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 444D, 445N, 447L, 457T, 458D
CDD
cd06647 (STKc_PAK_I)
active site cd06647

327I

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

328G

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

329Q

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

330G

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

331A

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

335V

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

348A

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

350K

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

379V

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

395M

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

396E

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

397Y

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

398L

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

399A

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

401G

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

402S

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

405D

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

440D

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

442K

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

443S

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

444D

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

445N

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

447L

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

457T

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

458D

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

461F

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

474T

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

475M

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

476V

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

477G

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

478T

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

480Y

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

507E

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

516L

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

517N

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

518E

active site
327I, 328G, 329Q, 330G, 331A, 335V, 348A, 350K, 379V, 395M, 396E, 397Y, 398L, 399A, 401G, 402S, 405D, 440D, 442K, 443S, 444D, 445N, 447L, 457T, 458D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)
polypeptide substr...

330G

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

331A

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

440D

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

442K

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

443S

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

444D

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

461F

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

474T

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

475M

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

476V

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

477G

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

478T

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

480Y

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

507E

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

516L

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

517N

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)

518E

polypeptide substrate binding site
330G, 331A, 440D, 442K, 443S, 444D, 461F, 474T, 475M, 476V, 477G, 478T, 480Y, 507E, 516L, 517N, 518E
CDD
cd06647 (STKc_PAK_I)
AID interaction si...

332S

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

366E

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

435H

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

437I

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

438H

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

439R

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

440D

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

458D

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

459F

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

486V

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

487V

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

489R

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

494P

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

519N

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

522R

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)

525Y

AID interaction site
332S, 366E, 435H, 437I, 438H, 439R, 440D, 458D, 459F, 486V, 487V, 489R, 494P, 519N, 522R, 525Y
CDD
cd06647 (STKc_PAK_I)
activation loop (A...

457T

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

458D

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

459F

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

460G

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

461F

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

462C

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

463A

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

464Q

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

465I

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

466S

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

467P

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

468E

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

469Q

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

470N

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

471K

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

472R

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

473T

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

474T

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

475M

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

476V

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

477G

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

478T

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

479P

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

480Y

activation loop (A-loop)
457T, 458D, 459F, 460G, 461F, 462C, 463A, 464Q, 465I, 466S, 467P, 468E, 469Q, 470N, 471K, 472R, 473T, 474T, 475M, 476V, 477G, 478T, 479P, 480Y
CDD
cd06647 (STKc_PAK_I)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component