KWMTBOMO09077

Protein

Length

628 amino acids

Protein family membership

Glycosyl transferase, family 8 (IPR002495)
- UDP-glucose:Glycoprotein Glucosyltransferase (IPR009448)

Domains and repeats

Domain
344 - 607
Nucleotide-diphospho-sugar transferases (IPR029044)

1 100 200 300 400 500 628

Detailed signature matches

IPR002495

Glycosyl transferase, family 8
1. PF01501 (Glyco_tran...)
  
  359 - 576
  
  Pfam
  PF01501 (Glyco_transf_8)
IPR009448

UDP-glucose:Glycoprotein Glucosyltransferase
1. PF06427 (UDP-g_GGTase)
  
  20 - 312
  
  Pfam
  PF06427 (UDP-g_GGTase)
IPR029044

Nucleotide-diphospho-sugar transferases
1. SSF53448 (Nucleotid...)
  
  344 - 607
  
  SUPERFAMILY
  SSF53448 (Nucleotide-diphospho-sugar transferases)
2. G3DSA:3.90.55...
  
  355 - 589
  
  GENE3D
  G3DSA:3.90.550.10 (G3DSA:3.90.550.10)

no IPR

Unintegrated signatures

cd06432 (GT8_HUGT1_...)

344 - 591

CDD
cd06432 (GT8_HUGT1_C_like)

Residue annotation

putative ligand bi...

349V

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

350A

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

351S

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

354L

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

355Y

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

428I

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

444F

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

446D

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

447A

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

448D

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

473F

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

502I

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

503S

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

504A

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

540D

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

541Q

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

564E

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

565T

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

579D

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

581C

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

582N

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)

587K

putative ligand binding site
349V, 350A, 351S, 354L, 355Y, 428I, 444F, 446D, 447A, 448D, 473F, 502I, 503S, 504A, 540D, 541Q, 564E, 565T, 579D, 581C, 582N, 587K
CDD
cd06432 (GT8_HUGT1_C_like)
metal binding site...

446D

metal binding site
446D, 448D, 579D
CDD
cd06432 (GT8_HUGT1_C_like)

448D

metal binding site
446D, 448D, 579D
CDD
cd06432 (GT8_HUGT1_C_like)

579D

metal binding site
446D, 448D, 579D
CDD
cd06432 (GT8_HUGT1_C_like)

GO term prediction

Biological Process

GO:0006486 protein glycosylation

Molecular Function

GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
GO:0016757 transferase activity, transferring glycosyl groups

Cellular Component

None predicted.

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Entry type

Status

Per-residue features