Protein

KWMTBOMO09073

Length
1,401 amino acids

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1401

Detailed signature matches

  1. Domain IPR001357
    BRCT domain
    1. G3DSA:3.40.50...
    2. SM00292 (BRCT_7)
    3. PS50172 (BRCT)
    4. PF12738 (PTCB-BRCT)
    5. SSF52113 (BRCT domain)
    6. cd00027 (BRCT)
  2. Domain IPR000219
    Dbl homology (DH) domain
    1. SSF48065 (DBL homol...)
    2. PS50010 (DH_2)
    3. SM00325 (RhoGEF_3)
    4. G3DSA:1.20.90...
    5. PF00621 (RhoGEF)
  3. Domain IPR011993
    PH domain-like
    1. SSF50729 (PH domain...)
  4. SITE IPR001331
    Guanine-nucleotide dissociation stimulator, CDC24, conserved site
    1. PS00741 (DH_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00160 (RhoGEF)
  2. cd01229 (PH_Ect2)
  3. mobidb-lite (disord...)

Residue annotation

  1. Dimer interface cd...
  2. BRCT sequence moti...
  3. GTPase interaction...

GO term prediction

Biological Process

GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity

Cellular Component

None predicted.