KWMTBOMO08906

Protein

Length

1,149 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
759 - 1,143
Ras guanine nucleotide exchange factor domain (IPR023578)
Domain
765 - 880
Ras-like guanine nucleotide exchange factor, N-terminal (IPR000651)
909 - 1,140
Ras guanine-nucleotide exchange factors catalytic domain (IPR001895)

1 200 400 600 800 1000 1149

Detailed signature matches

IPR023578

Ras guanine nucleotide exchange factor domain
1. SSF48366 (Ras GEF)
  
  759 - 1,143
  
  SUPERFAMILY
  SSF48366 (Ras GEF)
IPR000651

Ras-like guanine nucleotide exchange factor, N-terminal
1. PS50212 (RASGEF_NTER)
  
  765 - 880
  
  PROSITE profiles
  PS50212 (RASGEF_NTER)
IPR001895

Ras guanine-nucleotide exchange factors catalytic domain
1. PF00617 (RasGEF)
  
  916 - 1,086
  
  Pfam
  PF00617 (RasGEF)
2. cd00155 (RasGEF)
  
  909 - 1,133
  
  CDD
  cd00155 (RasGEF)
3. G3DSA:1.10.84...
  
  916 - 1,127
  
  GENE3D
  G3DSA:1.10.840.10 (G3DSA:1.10.840.10)
4. PS50009 (RASGEF_CAT)
  
  913 - 1,139
  
  PROSITE profiles
  PS50009 (RASGEF_CAT)
5. SM00147 (RasGEF_3)
  
  909 - 1,140
  
  SMART
  SM00147 (RasGEF_3)
IPR019804

Ras guanine-nucleotide exchange factor, conserved site
1. PS00720 (RASGEF)
  
  1,055 - 1,085
  
  PROSITE patterns
  PS00720 (RASGEF)

no IPR

Unintegrated signatures

G3DSA:1.20.87...

735 - 915

GENE3D
G3DSA:1.20.870.10 (G3DSA:1.20.870.10)
mobidb-lite (disord...)

9 - 38

MobiDB Lite
mobidb-lite (disorder_prediction)

612 - 691

MobiDB Lite
mobidb-lite (disorder_prediction)

711 - 747

MobiDB Lite
mobidb-lite (disorder_prediction)

61 - 101

MobiDB Lite
mobidb-lite (disorder_prediction)

229 - 321

MobiDB Lite
mobidb-lite (disorder_prediction)

335 - 362

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Ras interaction si...

940W

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

941P

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

952L

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

953T

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

955F

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

956T

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

957E

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

959F

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

960N

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

963S

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

964Y

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

967R

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,000N

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,003L

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,004A

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,006V

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,007S

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,008A

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,010D

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,011S

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,012P

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,013P

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,015R

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,016R

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,031C

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,034I

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,039S

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,040F

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,041R

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,044R

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,057Y

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,058I

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,059G

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,062L

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,063Q

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,064D

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,066T

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,067F

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,068V

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,070I

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,071G

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,072N

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,073Q

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,088Q

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,092I

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,127E

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,130W

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

1,131Q

Ras interaction site
940W, 941P, 952L, 953T, 955F, 956T, 957E, 959F, 960N, 963S, 964Y, 967R, 1,000N, 1,003L, 1,004A, 1,006V, 1,007S, 1,008A, 1,010D, 1,011S, 1,012P, 1,013P, 1,015R, 1,016R, 1,031C, 1,034I, 1,039S, 1,040F, 1,041R, 1,044R, 1,057Y, 1,058I, 1,059G, 1,062L, 1,063Q, 1,064D, 1,066T, 1,067F, 1,068V, 1,070I, 1,071G, 1,072N, 1,073Q, 1,088Q, 1,092I, 1,127E, 1,130W, 1,131Q
CDD
cd00155 (RasGEF)

GO term prediction

Biological Process

GO:0007264 small GTPase mediated signal transduction

Molecular Function

GO:0005085 guanyl-nucleotide exchange factor activity

Cellular Component