Protein

KWMTBOMO08649

Length
801 amino acids

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 801

Detailed signature matches

  1. Domain IPR001715
    Calponin homology domain
    1. G3DSA:1.10.41...
    2. SM00033 (ch_5)
    3. PF00307 (CH)
    4. PS50021 (CH)
    5. SSF47576 (Calponin-...)
  2. Domain IPR000219
    Dbl homology (DH) domain
    1. SSF48065 (DBL homol...)
    2. PS50010 (DH_2)
    3. SM00325 (RhoGEF_3)
    4. PF00621 (RhoGEF)
    5. G3DSA:1.20.90...
  3. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  4. Domain IPR001849
    Pleckstrin homology domain
    1. PS50003 (PH_DOMAIN)
    2. SM00233 (PH_update)
    3. PF00169 (PH)
  5. Domain IPR002219
    Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
    1. SM00109 (c1_12)
    2. PF00130 (C1_1)
    3. PS00479 (ZF_DAG_PE_1)
    4. PS50081 (ZF_DAG_PE_2)
    5. cd00029 (C1)
  6. Domain IPR000980
    SH2 domain
    1. PF00017 (SH2)
    2. SM00252 (SH2_5)
    3. PS50001 (SH2)
    4. SSF55550 (SH2 domain)
    5. G3DSA:3.30.50...
  7. Domain IPR001452
    SH3 domain
    1. PF00018 (SH3_1)
    2. PS50002 (SH3)
    3. SSF50044 (SH3-domain)
    4. SM00326 (SH3_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.30.30.40
  2. G3DSA:3.30.60.20
  3. cd00160 (RhoGEF)
  4. cd00174 (SH3)
  5. cd01223 (PH_Vav)

Residue annotation

  1. GTPase interaction...
  2. zinc binding sites...
  3. putative DAG/PE bi...
  4. putative RAS inter...
  5. peptide ligand bin...

GO term prediction

Biological Process

GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding

Cellular Component

None predicted.