Protein

KWMTBOMO08143

Length
628 amino acids

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 628

Detailed signature matches

  1. Family IPR003701
    DNA double-strand break repair protein Mre11
    1. PIRSF000882 (DSB_re...)
    2. TIGR00583
  2. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. G3DSA:3.60.21.10
    2. SSF56300 (Metallo-d...)
  3. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  4. Domain IPR007281
    Mre11, DNA-binding
    1. PF04152 (Mre11_DNA_...)
    2. SM01347 (Mre11_DNA_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd00840 (MPP_Mre11_N)
  3. mobidb-lite (disord...)

Residue annotation

  1. metal binding site...
  2. active site cd00840
  3. DNA binding site c...
  4. heterodimer interf...
  5. homodimer interfac...

GO term prediction

Biological Process

GO:0006302 double-strand break repair

Molecular Function

GO:0004519 endonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding

Cellular Component

GO:0005634 nucleus
GO:0030870 Mre11 complex