KWMTBOMO08044

Protein

Length

632 amino acids

Protein family membership

AP endonuclease 1 (IPR004808)

Domains and repeats

Domain
359 - 623
Endonuclease/exonuclease/phosphatase (IPR005135)

1 100 200 300 400 500 632

Detailed signature matches

IPR004808

AP endonuclease 1
1. PS51435 (AP_NUCLEAS...)
  
  371 - 624
  
  PROSITE profiles
  PS51435 (AP_NUCLEASE_F1_4)
2. TIGR00633
  
  372 - 622
  
  TIGRFAMs
  TIGR00633 (TIGR00633)
IPR005135

Endonuclease/exonuclease/phosphatase
1. G3DSA:3.60.10.10
  
  359 - 622
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
2. PF03372 (Exo_endo_phos)
  
  374 - 615
  
  Pfam
  PF03372 (Exo_endo_phos)
3. SSF56219 (DNase I-like)
  
  371 - 623
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
IPR020847

AP endonuclease 1, binding site
1. PS00726 (AP_NUCLEAS...)
  
  398 - 407
  
  PROSITE patterns
  PS00726 (AP_NUCLEASE_F1_1)
IPR020848

AP endonuclease 1, conserved site
1. PS00727 (AP_NUCLEAS...)
  
  557 - 573
  
  PROSITE patterns
  PS00727 (AP_NUCLEASE_F1_2)

no IPR

Unintegrated signatures

Coil

269 - 289

COILS
Coil (Coil)
TIGR00195

372 - 620

TIGRFAMs
TIGR00195 (TIGR00195)
cd09087 (Ape1-like_...)

371 - 622

CDD
cd09087 (Ape1-like_AP-endo)
mobidb-lite (disord...)

1 - 354

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

active site cd09087

377N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

379D

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

380G

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

381I

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

382R

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

383A

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

387K

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

405E

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

407K

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

412K

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

434G

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

435Y

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

478Y

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

481N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

517D

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

529N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

531K

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

533N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

536N

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

537A

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

572F

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

574T

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

575Y

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

576M

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

582K

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

584V

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

586W

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

588L

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

589D

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

active site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 589D, 615H
CDD
cd09087 (Ape1-like_AP-endo)
putative phosphate...

377N

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

405E

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

478Y

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

481N

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

517D

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

putative phosphate binding site
377N, 405E, 478Y, 481N, 517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)
putative catalytic...

377N

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

405E

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

478Y

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

517D

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

589D

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

614D

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

putative catalytic site
377N, 405E, 478Y, 517D, 519N, 589D, 614D, 615H
CDD
cd09087 (Ape1-like_AP-endo)
DNA binding site c...

377N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

379D

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

380G

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

381I

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

382R

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

383A

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

387K

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

405E

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

407K

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

412K

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

434G

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

435Y

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

478Y

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

481N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

517D

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

529N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

531K

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

533N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

536N

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

537A

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

572F

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

574T

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

575Y

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

576M

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

582K

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

584V

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

586W

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

588L

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

DNA binding site
377N, 379D, 380G, 381I, 382R, 383A, 387K, 405E, 407K, 412K, 434G, 435Y, 478Y, 481N, 517D, 519N, 529N, 531K, 533N, 536N, 537A, 572F, 574T, 575Y, 576M, 582K, 584V, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)
metal binding site...

379D

metal binding site A
379D, 405E, 614D
CDD
cd09087 (Ape1-like_AP-endo)

405E

metal binding site A
379D, 405E, 614D
CDD
cd09087 (Ape1-like_AP-endo)

614D

metal binding site A
379D, 405E, 614D
CDD
cd09087 (Ape1-like_AP-endo)
AP binding site cd...

478Y

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

481N

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

517D

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

537A

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

572F

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

586W

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

588L

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

AP binding site
478Y, 481N, 517D, 519N, 537A, 572F, 586W, 588L, 615H
CDD
cd09087 (Ape1-like_AP-endo)
metal binding site...

517D

metal binding site B
517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

519N

metal binding site B
517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

615H

metal binding site B
517D, 519N, 615H
CDD
cd09087 (Ape1-like_AP-endo)

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity

Cellular Component

GO:0005622 intracellular

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Entry type

Status

Per-residue features