KWMTBOMO07687

Protein

Length

341 amino acids

Protein family membership

Peptidase T2, asparaginase 2 (IPR000246)

Domains and repeats

Domain
24 - 332
Nucleophile aminohydrolases, N-terminal (IPR029055)

1 50 100 150 200 250 300 341

Detailed signature matches

IPR000246

Peptidase T2, asparaginase 2
1. PF01112 (Asparagina...)
  
  33 - 331
  
  Pfam
  PF01112 (Asparaginase_2)
IPR029055

Nucleophile aminohydrolases, N-terminal
1. SSF56235 (N-termina...)
  
  24 - 332
  
  SUPERFAMILY
  SSF56235 (N-terminal nucleophile aminohydrolases (Ntn hydrolases))

no IPR

Unintegrated signatures

cd04513 (Glycosylas...)

26 - 327

CDD
cd04513 (Glycosylasparaginase)

Residue annotation

active site cd04513

31W

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

202H

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

203D

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

204T

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

222T

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

232R

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)

255T

active site
31W, 202H, 203D, 204T, 222T, 232R, 255T
CDD
cd04513 (Glycosylasparaginase)
dimer interface cd...

94M

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

95N

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

96I

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

101G

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

121H

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

122S

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

123F

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

124L

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

125V

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

127E

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

128L

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

131Q

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

132F

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

230P

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

231G

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

232R

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

233I

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

238I

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

239P

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

240G

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

244Y

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

259D

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

262L

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

268F

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

272E

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)

290R

dimer interface
94M, 95N, 96I, 101G, 121H, 122S, 123F, 124L, 125V, 127E, 128L, 131Q, 132F, 230P, 231G, 232R, 233I, 238I, 239P, 240G, 244Y, 259D, 262L, 268F, 272E, 290R
CDD
cd04513 (Glycosylasparaginase)
catalytic nucleoph...

204T

catalytic nucleophile
204T
CDD
cd04513 (Glycosylasparaginase)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO07687

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component