KWMTBOMO07605

Protein

Length

489 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
17 - 464
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 489

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  93 - 428
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  26 - 464
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  97 - 460
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  17 - 53
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  85 - 464
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
IPR005829

Sugar transporter, conserved site
1. PS00216 (SUGAR_TRAN...)
  
  113 - 130
  
  PROSITE patterns
  PS00216 (SUGAR_TRANSPORT_1)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

88 - 234

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

326 - 463

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

99G

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

102H

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

103S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

106Y

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

110L

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

111L

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

113I

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

114G

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

160G

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

161D

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

164S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

165P

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

168I

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

169L

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

183Y

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

184L

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

187S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

188L

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

194S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

305T

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

308N

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

309Y

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

312I

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

313I

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

316V

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

326F

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

330S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

333D

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

337N

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

386K

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

389S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

390S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

393F

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

397Y

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

398M

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

401S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

412M

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

413H

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

416C

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

417S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

420G

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

421R

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

424S

putative substrate translocation pore
99G, 102H, 103S, 106Y, 110L, 111L, 113I, 114G, 160G, 161D, 164S, 165P, 168I, 169L, 183Y, 184L, 187S, 188L, 194S, 305T, 308N, 309Y, 312I, 313I, 316V, 326F, 330S, 333D, 337N, 386K, 389S, 390S, 393F, 397Y, 398M, 401S, 412M, 413H, 416C, 417S, 420G, 421R, 424S
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features