KWMTBOMO07272

Protein

Length

551 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
25 - 464
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 551

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  42 - 418
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  31 - 464
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  75 - 460
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  25 - 460
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

259 - 462

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

35 - 236

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
mobidb-lite (disord...)

1 - 21

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

86D

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

89Y

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

90F

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

93Y

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

97Q

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

98V

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

100G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

101G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

149E

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

150G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

153Y

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

154P

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

157H

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

158G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

161R

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

173A

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

174T

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

177F

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

178C

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

184I

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

280T

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

283F

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

284C

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

287V

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

288I

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

291S

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

305S

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

309G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

313H

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

316M

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

320V

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

381G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

384I

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

385S

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

388N

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

392L

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

393D

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

402L

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

403M

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

406S

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

407N

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

410G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

411T

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

414G

putative substrate translocation pore
86D, 89Y, 90F, 93Y, 97Q, 98V, 100G, 101G, 149E, 150G, 153Y, 154P, 157H, 158G, 161R, 173A, 174T, 177F, 178C, 184I, 280T, 283F, 284C, 287V, 288I, 291S, 305S, 309G, 313H, 316M, 320V, 381G, 384I, 385S, 388N, 392L, 393D, 402L, 403M, 406S, 407N, 410G, 411T, 414G
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO07272

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component