KWMTBOMO06889

Protein

Length

2,439 amino acids

Protein family membership

Protein of unknown function DUF1759 (IPR005312)

Retrotransposon, Pao (IPR008042)

Domains and repeats

Domain
64 - 337
Reverse transcriptase domain (IPR000477)
994 - 1,025
Zinc finger, CCHC-type (IPR001878)
2,116 - 2,300
Ribonuclease H-like domain (IPR012337)
Integrase, catalytic core (IPR001584)

1 500 1000 1500 2000 2439

Detailed signature matches

IPR005312

Protein of unknown function DUF1759
1. PF03564 (DUF1759)
  
  805 - 941
  
  Pfam
  PF03564 (DUF1759)
IPR008042

Retrotransposon, Pao
1. PF05380 (Peptidase_A17)
  
  1,626 - 1,787
  
  Pfam
  PF05380 (Peptidase_A17)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  84 - 336
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  64 - 337
  
  PROSITE profiles
  PS50878 (RT_POL)
IPR001878

Zinc finger, CCHC-type
1. PS50158 (ZF_CCHC)
  
  1,004 - 1,021
  
  PROSITE profiles
  PS50158 (ZF_CCHC)
2. SSF57756 (Retroviru...)
  
  994 - 1,025
  
  SUPERFAMILY
  SSF57756 (Retrovirus zinc finger-like domains)
IPR012337

Ribonuclease H-like domain
1. G3DSA:3.30.42...
  
  2,116 - 2,279
  
  GENE3D
  G3DSA:3.30.420.10 (G3DSA:3.30.420.10)
2. SSF53098 (Ribonucle...)
  
  2,117 - 2,281
  
  SUPERFAMILY
  SSF53098 (Ribonuclease H-like)
IPR001584

Integrase, catalytic core
1. PS50994 (INTEGRASE)
  
  2,118 - 2,300
  
  PROSITE profiles
  PS50994 (INTEGRASE)
2. PF00665 (rve)
  
  2,120 - 2,245
  
  Pfam
  PF00665 (rve)

no IPR

Unintegrated signatures

Coil

2,196 - 2,216

COILS
Coil (Coil)

656 - 707

COILS
Coil (Coil)
SSF56672 (DNA/RNA p...)

1,357 - 1,814

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)

28 - 305

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01644 (RT_pepA17)

1,389 - 1,604

CDD
cd01644 (RT_pepA17)
cd01650 (RT_nLTR_like)

78 - 334

CDD
cd01650 (RT_nLTR_like)
mobidb-lite (disord...)

1,926 - 1,961

MobiDB Lite
mobidb-lite (disorder_prediction)

691 - 711

MobiDB Lite
mobidb-lite (disorder_prediction)

621 - 650

MobiDB Lite
mobidb-lite (disorder_prediction)

2,420 - 2,439

MobiDB Lite
mobidb-lite (disorder_prediction)

971 - 1,004

MobiDB Lite
mobidb-lite (disorder_prediction)

459 - 595

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative NTP bindi...

163D

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

164I

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

165E

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

166K

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

167A

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

168F

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

222Q

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)

259D

putative NTP binding site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 259D
CDD
cd01650 (RT_nLTR_like)
putative active si...

163D

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

164I

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

165E

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

166K

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

167A

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

168F

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

222Q

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

223G

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

257F

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

259D

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

260D

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

333L

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)

334G

putative active site
163D, 164I, 165E, 166K, 167A, 168F, 222Q, 223G, 257F, 259D, 260D, 333L, 334G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

223G

putative nucleic acid binding site
223G
CDD
cd01650 (RT_nLTR_like)
putative NTP bindi...

1,452D

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,453I

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,454T

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,455E

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,456M

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,457F

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,492F

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)

1,530D

putative NTP binding site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,530D
CDD
cd01644 (RT_pepA17)
putative active si...

1,452D

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,453I

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,454T

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,455E

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,456M

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,457F

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,492F

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,493G

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,528Y

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,530D

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,531D

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,595L

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)

1,596G

putative active site
1,452D, 1,453I, 1,454T, 1,455E, 1,456M, 1,457F, 1,492F, 1,493G, 1,528Y, 1,530D, 1,531D, 1,595L, 1,596G
CDD
cd01644 (RT_pepA17)
putative nucleic a...

1,493G

putative nucleic acid binding site
1,493G
CDD
cd01644 (RT_pepA17)

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO06889

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component