KWMTBOMO06774

Protein

Length

384 amino acids

Protein family membership

Arf GTPase activating protein (IPR001164)

Domains and repeats

Domain
129 - 231
PH domain-like (IPR011993)
Pleckstrin homology domain (IPR001849)
219 - 363
PH domain-like (IPR011993)
Pleckstrin homology domain (IPR001849)

1 50 100 150 200 250 300 350 384

Detailed signature matches

IPR001164

Arf GTPase activating protein
1. PS50115 (ARFGAP)
  
  6 - 127
  
  PROSITE profiles
  PS50115 (ARFGAP)
2. SM00105 (arf_gap_3)
  
  6 - 127
  
  SMART
  SM00105 (arf_gap_3)
3. PR00405 (REVINTRACTNG)
  
  58 - 79
  
  PRINTS
  PR00405 (REVINTRACTNG)
  
  18 - 37
  
  PRINTS
  PR00405 (REVINTRACTNG)
  
  37 - 54
  
  PRINTS
  PR00405 (REVINTRACTNG)
4. PF01412 (ArfGap)
  
  7 - 121
  
  Pfam
  PF01412 (ArfGap)
IPR011993

PH domain-like
1. G3DSA:2.30.29.30
  
  131 - 228
  
  GENE3D
  G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
  
  243 - 361
  
  GENE3D
  G3DSA:2.30.29.30 (G3DSA:2.30.29.30)
2. SSF50729 (PH domain...)
  
  131 - 227
  
  SUPERFAMILY
  SSF50729 (PH domain-like)
  
  219 - 363
  
  SUPERFAMILY
  SSF50729 (PH domain-like)
IPR001849

Pleckstrin homology domain
1. PS50003 (PH_DOMAIN)
  
  251 - 354
  
  PROSITE profiles
  PS50003 (PH_DOMAIN)
  
  129 - 229
  
  PROSITE profiles
  PS50003 (PH_DOMAIN)
2. SM00233 (PH_update)
  
  130 - 231
  
  SMART
  SM00233 (PH_update)
  
  252 - 356
  
  SMART
  SM00233 (PH_update)
3. PF00169 (PH)
  
  254 - 354
  
  Pfam
  PF00169 (PH)
  
  132 - 225
  
  Pfam
  PF00169 (PH)

no IPR

Unintegrated signatures

SSF57863 (ArfGap/Re...)

5 - 122

SUPERFAMILY
SSF57863 (ArfGap/RecO-like zinc finger)
cd01251 (PH2_ADAP)

251 - 355

CDD
cd01251 (PH2_ADAP)
cd13252 (PH1_ADAP)

130 - 237

CDD
cd13252 (PH1_ADAP)

Residue annotation

KIF12B binding sit...

137M

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

143D

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

145R

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

146Y

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

147Q

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

185P

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

186P

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

187K

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

188I

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

189G

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

190H

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

191M

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

192N

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

210Y

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)

212E

KIF12B binding site
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 212E
CDD
cd13252 (PH1_ADAP)
heterotetramer int...

137M

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

143D

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

145R

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

146Y

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

147Q

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

185P

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

186P

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

187K

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

188I

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

189G

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

190H

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

191M

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

192N

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

210Y

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

211H

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

212E

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

213E

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

215E

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)

216V

heterotetramer interface
137M, 143D, 145R, 146Y, 147Q, 185P, 186P, 187K, 188I, 189G, 190H, 191M, 192N, 210Y, 211H, 212E, 213E, 215E, 216V
CDD
cd13252 (PH1_ADAP)
phosphoinositide b...

138K

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

141K

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

142E

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

143D

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

149R

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

162Y

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

164V

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

171K

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)

205R

phosphoinositide binding site
138K, 141K, 142E, 143D, 149R, 162Y, 164V, 171K, 205R
CDD
cd13252 (PH1_ADAP)
putative phosphoin...

260K

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

268A

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

270R

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

272R

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

283Y

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

293K

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

330R

putative phosphoinositide binding site
260K, 268A, 270R, 272R, 283Y, 293K, 330R
CDD
cd01251 (PH2_ADAP)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005096 GTPase activator activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO06774

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component