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Entry type
Status
Per-residue features
Colour by
Protein
KWMTBOMO06463
Length
1,543 amino acids
Protein family membership
- DNA topoisomerase, type IIA (IPR001241)
- DNA topoisomerase II, eukaryotic-type (IPR001154)
Domains and repeats
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Domain34 - 281
- Histidine kinase-like ATPase, C-terminal domain (IPR003594)
458 - 575- Toprim domain (IPR006171)
576 - 714- C-terminal associated domain of TOPRIM (IPR031660)
718 - 898899 - 999- Arginine repressor C-terminal-like domain (IPR024946)
1,016 - 1,204 -
Domain259 - 429
- Ribosomal protein S5 domain 2-type fold (IPR020568)
430 - 1,201- DNA topoisomerase, type IIA-like domain (IPR013760)
- DNA topoisomerase, type IIA, central domain (IPR013759)
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Domain696 - 1,188
1
200
400
600
800
1000
1200
1400
1543
Detailed signature matches
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PR01158 (TOPISMRASEII)1,008 - 1,034552 - 567443 - 453458 - 465744 - 767821 - 841791 - 813572 - 583506 - 519619 - 631925 - 939
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292 - 421
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430 - 597
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-
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718 - 898
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-
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899 - 999
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-
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1,016 - 1,204
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no IPR
Unintegrated signatures
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598 - 631
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cd00075 (HATPase_c)84 - 188
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cd00187 (TOP4c)714 - 1,190
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cd03365 (TOPRIM_Top...)458 - 578
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cd03481 (TopoIIA_Tr...)269 - 421
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mobidb-lite (disord...)1,201 - 1,2448 - 301,256 - 1,5431,102 - 1,129
Residue annotation
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ATP binding site c...90EATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)94NATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)97DATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)121VATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)123NATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)125GATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)127GATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)128IATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)167GATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)168YATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)169GATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)170AATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)182VATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c)184TATP binding site
90E, 94N, 97D, 121V, 123N, 125G, 127G, 128I, 167G, 168Y, 169G, 170A, 182V, 184T
CDD
cd00075 (HATPase_c) -
Mg2+ binding site ...94N
-
G-X-G motif cd00075
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dimer interface cd...359Q363H378D379S
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ATP binding cd03481
-
putative metal-bin...
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active site cd03365464E465G468A544D546D548D
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CAP-like domain cd...714NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)715VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)716RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)717SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)718ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)719PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)720SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)721MCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)722ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)723DCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)724GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)725LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)726KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)727PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)728GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)729QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)730RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)731KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)732VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)733ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)734FCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)735TCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)736CCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)737ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)738KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)739RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)740NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)743RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)744ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)745VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)746KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)747VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)748ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)749QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)750LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)751ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)752GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)753SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)754VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)755ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)756ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)757HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)758SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)760YCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)761HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)762HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)763GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)764ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)765QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)766SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)767LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)768ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)769MCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)770TCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)771ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)772VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)773NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)774LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)775ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)776QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)777NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)778YCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)781SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)782NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)783NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)784ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)785NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)786LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)787LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)788ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)789PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)790RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)791GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)792QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)793FCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)794GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)795TCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)799GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)800GCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)801KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)802DCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)803SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)804ACAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)805SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)806PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)807RCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)808YCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)809ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)810FCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)811TCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)812LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)813MCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)814SCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)815PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)816LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)817TCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)819LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)820ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)821FCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)822HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)823PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)824HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)825DCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)826DCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)827PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)828LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)829LCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)830VCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)831HCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)832ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)833FCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)834ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)835DCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)836NCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)837QCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)838KCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)839ICAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)840ECAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)841PCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c)844YCAP-like domain
714N, 715V, 716R, 717S, 718I, 719P, 720S, 721M, 722I, 723D, 724G, 725L, 726K, 727P, 728G, 729Q, 730R, 731K, 732V, 733I, 734F, 735T, 736C, 737I, 738K, 739R, 740N, 743R, 744E, 745V, 746K, 747V, 748A, 749Q, 750L, 751A, 752G, 753S, 754V, 755A, 756E, 757H, 758S, 760Y, 761H, 762H, 763G, 764E, 765Q, 766S, 767L, 768A, 769M, 770T, 771I, 772V, 773N, 774L, 775A, 776Q, 777N, 778Y, 781S, 782N, 783N, 784I, 785N, 786L, 787L, 788E, 789P, 790R, 791G, 792Q, 793F, 794G, 795T, 799G, 800G, 801K, 802D, 803S, 804A, 805S, 806P, 807R, 808Y, 809I, 810F, 811T, 812L, 813M, 814S, 815P, 816L, 817T, 819L, 820I, 821F, 822H, 823P, 824H, 825D, 826D, 827P, 828L, 829L, 830V, 831H, 832E, 833F, 834E, 835D, 836N, 837Q, 838K, 839I, 840E, 841P, 844Y
CDD
cd00187 (TOP4c) -
Active site cd00187808Y
-
primary dimer inte...1,057Lprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,058Eprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,059Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,066Iprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,067Eprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,068Nprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,069Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,072Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,142Nprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,143Yprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,144Lprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,145Lprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,146Gprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,147Mprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,148Sprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,149Mprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,150Wprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,151Mprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,152Lprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,153Tprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,154Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,155Eprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,156Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,157Kprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)1,158Dprimary dimer interface
1,057L, 1,058E, 1,059K, 1,066I, 1,067E, 1,068N, 1,069K, 1,072K, 1,142N, 1,143Y, 1,144L, 1,145L, 1,146G, 1,147M, 1,148S, 1,149M, 1,150W, 1,151M, 1,152L, 1,153T, 1,154K, 1,155E, 1,156K, 1,157K, 1,158D
CDD
cd00187 (TOP4c)
GO term prediction
Biological Process
GO:0006259 DNA metabolic process
GO:0006265 DNA topological change
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005524 ATP binding
Cellular Component
None predicted.