KWMTBOMO05992

Protein

Length

244 amino acids

Protein family membership

Short-chain dehydrogenase/reductase SDR (IPR002347)

Domains and repeats

Domain
1 - 244
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 244

Detailed signature matches

IPR002347

Short-chain dehydrogenase/reductase SDR
1. PF00106 (adh_short)
  
  2 - 206
  
  Pfam
  PF00106 (adh_short)
2. PR00080 (SDRFAMILY)
  
  78 - 89
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  166 - 185
  
  PRINTS
  PR00080 (SDRFAMILY)
  
  143 - 151
  
  PRINTS
  PR00080 (SDRFAMILY)
3. PR00081 (GDHRDH)
  
  78 - 89
  
  PRINTS
  PR00081 (GDHRDH)
  
  187 - 204
  
  PRINTS
  PR00081 (GDHRDH)
  
  137 - 153
  
  PRINTS
  PR00081 (GDHRDH)
  
  166 - 185
  
  PRINTS
  PR00081 (GDHRDH)
  
  3 - 20
  
  PRINTS
  PR00081 (GDHRDH)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  1 - 244
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  1 - 244
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)

no IPR

Unintegrated signatures

cd05325 (carb_red_s...)

4 - 244

CDD
cd05325 (carb_red_sniffer_like_SDR_c)

Residue annotation

NADP binding site ...

8G

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

10N

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

11R

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

12G

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

13L

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

35R

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

57D

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

58V

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

86N

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

87A

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

88G

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

89I

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

110V

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

148M

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

149S

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

150S

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

166Y

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

170K

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

195H

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

196P

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

197G

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

198W

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

199V

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

201T

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

203M

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

204G

NADP binding site
8G, 10N, 11R, 12G, 13L, 35R, 57D, 58V, 86N, 87A, 88G, 89I, 110V, 148M, 149S, 150S, 166Y, 170K, 195H, 196P, 197G, 198W, 199V, 201T, 203M, 204G
CDD
cd05325 (carb_red_sniffer_like_SDR_c)
homodimer interfac...

58V

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

68T

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

104L

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

109T

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

112T

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

113V

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

114A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

117M

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

120K

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

121S

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

152L

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

153G

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

154S

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

155I

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

156A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

157Q

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

158N

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

164Y

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

167R

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

168C

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

171A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

172A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

175A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

176A

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

178K

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

179S

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

182I

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

183D

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

243P

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

244W

homodimer interface
58V, 68T, 104L, 109T, 112T, 113V, 114A, 117M, 120K, 121S, 152L, 153G, 154S, 155I, 156A, 157Q, 158N, 164Y, 167R, 168C, 171A, 172A, 175A, 176A, 178K, 179S, 182I, 183D, 243P, 244W
CDD
cd05325 (carb_red_sniffer_like_SDR_c)
active site cd05325

111N

active site
111N, 150S, 166Y, 170K
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

150S

active site
111N, 150S, 166Y, 170K
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

166Y

active site
111N, 150S, 166Y, 170K
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

170K

active site
111N, 150S, 166Y, 170K
CDD
cd05325 (carb_red_sniffer_like_SDR_c)

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO05992

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component