KWMTBOMO05764

Protein

Length

1,309 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
27 - 479
Periplasmic binding protein-like I (IPR028082)
Receptor, ligand binding region (IPR001828)
531 - 869
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Serine-threonine/tyrosine-protein kinase catalytic domain (IPR001245)
Domain
863 - 1,082
Nucleotide cyclase (IPR029787)
Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054)

1 200 400 600 800 1000 1200 1309

Detailed signature matches

IPR028082

Periplasmic binding protein-like I
1. SSF53822 (Periplasm...)
  
  27 - 479
  
  SUPERFAMILY
  SSF53822 (Periplasmic binding protein-like I)
IPR001828

Receptor, ligand binding region
1. PF01094 (ANF_receptor)
  
  49 - 425
  
  Pfam
  PF01094 (ANF_receptor)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  573 - 869
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  531 - 824
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
IPR001245

Serine-threonine/tyrosine-protein kinase catalytic domain
1. PF07714 (Pkinase_Tyr)
  
  572 - 824
  
  Pfam
  PF07714 (Pkinase_Tyr)
IPR029787

Nucleotide cyclase
1. SSF55073 (Nucleotid...)
  
  886 - 1,075
  
  SUPERFAMILY
  SSF55073 (Nucleotide cyclase)
IPR001054

Adenylyl cyclase class-3/4/guanylyl cyclase
1. PS50125 (GUANYLATE_...)
  
  899 - 1,029
  
  PROSITE profiles
  PS50125 (GUANYLATE_CYCLASE_2)
2. SM00044 (cyc_6)
  
  863 - 1,057
  
  SMART
  SM00044 (cyc_6)
3. G3DSA:3.30.70...
  
  887 - 1,082
  
  GENE3D
  G3DSA:3.30.70.1230 (G3DSA:3.30.70.1230)
4. PF00211 (Guanylate_cyc)
  
  891 - 1,075
  
  Pfam
  PF00211 (Guanylate_cyc)
IPR018297

Adenylyl cyclase class-4/guanylyl cyclase, conserved site
1. PS00452 (GUANYLATE_...)
  
  1,006 - 1,029
  
  PROSITE patterns
  PS00452 (GUANYLATE_CYCLASE_1)

no IPR

Unintegrated signatures

Coil

836 - 863

COILS
Coil (Coil)
G3DSA:1.10.51...

637 - 837

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

569 - 636

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
G3DSA:3.40.50...

309 - 413

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)

25 - 142

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)

414 - 479

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)

146 - 306

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
cd07302 (CHD)

898 - 1,074

CDD
cd07302 (CHD)
mobidb-lite (disord...)

1,089 - 1,113

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

nucleotidyl bindin...

902F

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

904D

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

905I

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

906V

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

907G

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

908F

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

909T

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

944E

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

946I

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

947G

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

948D

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

951M

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,016C

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,017L

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,018F

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,022V

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,023N

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,026S

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,027R

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)

1,064K

nucleotidyl binding site
902F, 904D, 905I, 906V, 907G, 908F, 909T, 944E, 946I, 947G, 948D, 951M, 1,016C, 1,017L, 1,018F, 1,022V, 1,023N, 1,026S, 1,027R, 1,064K
CDD
cd07302 (CHD)
metal binding site...

904D

metal binding site
904D, 948D
CDD
cd07302 (CHD)

948D

metal binding site
904D, 948D
CDD
cd07302 (CHD)
dimer interface cd...

909T

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

921V

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

924L

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

925N

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

928Y

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

932D

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

944E

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

945T

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,004V

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,007V

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,017L

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,018F

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,019G

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,020D

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,023N

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

1,064K

dimer interface
909T, 921V, 924L, 925N, 928Y, 932D, 944E, 945T, 1,004V, 1,007V, 1,017L, 1,018F, 1,019G, 1,020D, 1,023N, 1,064K
CDD
cd07302 (CHD)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0016849 phosphorus-oxygen lyase activity

Cellular Component