KWMTBOMO05720

Protein

Length

2,488 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
193 - 253
DDT domain (IPR018501)
293 - 333
WHIM1 domain (IPR028942)
341 - 396
Zinc finger, RING/FYVE/PHD-type (IPR013083)
Zinc finger, FYVE/PHD-type (IPR011011)
Zinc finger, PHD-type (IPR001965)
Zinc finger, PHD-finger (IPR019787)
2,084 - 2,100
Bromodomain (IPR001487)
2,254 - 2,309
Zinc finger, RING/FYVE/PHD-type (IPR013083)
Zinc finger, FYVE/PHD-type (IPR011011)
Zinc finger, PHD-type (IPR001965)
Zinc finger, PHD-finger (IPR019787)
2,300 - 2,367
Zinc finger, RING/FYVE/PHD-type (IPR013083)
Zinc finger, FYVE/PHD-type (IPR011011)
Zinc finger, PHD-type (IPR001965)
Zinc finger, PHD-finger (IPR019787)
2,373 - 2,486
Bromodomain (IPR001487)

1 500 1000 1500 2000 2488

Detailed signature matches

IPR018501

DDT domain
1. SM00571 (testlast3)
  
  193 - 253
  
  SMART
  SM00571 (testlast3)
2. PF02791 (DDT)
  
  197 - 250
  
  Pfam
  PF02791 (DDT)
3. PS50827 (DDT)
  
  193 - 253
  
  PROSITE profiles
  PS50827 (DDT)
IPR028942

WHIM1 domain
1. PF15612 (WHIM1)
  
  293 - 333
  
  Pfam
  PF15612 (WHIM1)
IPR013083

Zinc finger, RING/FYVE/PHD-type
1. G3DSA:3.30.40.10
  
  2,310 - 2,365
  
  GENE3D
  G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
  
  2,254 - 2,309
  
  GENE3D
  G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
  
  344 - 396
  
  GENE3D
  G3DSA:3.30.40.10 (G3DSA:3.30.40.10)
IPR011011

Zinc finger, FYVE/PHD-type
1. SSF57903 (FYVE/PHD ...)
  
  341 - 396
  
  SUPERFAMILY
  SSF57903 (FYVE/PHD zinc finger)
  
  2,311 - 2,367
  
  SUPERFAMILY
  SSF57903 (FYVE/PHD zinc finger)
  
  2,256 - 2,309
  
  SUPERFAMILY
  SSF57903 (FYVE/PHD zinc finger)
IPR001965

Zinc finger, PHD-type
1. SM00249 (PHD_3)
  
  2,316 - 2,363
  
  SMART
  SM00249 (PHD_3)
  
  2,260 - 2,307
  
  SMART
  SM00249 (PHD_3)
  
  346 - 389
  
  SMART
  SM00249 (PHD_3)
IPR019787

Zinc finger, PHD-finger
1. PS50016 (ZF_PHD_2)
  
  2,300 - 2,365
  
  PROSITE profiles
  PS50016 (ZF_PHD_2)
  
  344 - 391
  
  PROSITE profiles
  PS50016 (ZF_PHD_2)
2. PF00628 (PHD)
  
  2,261 - 2,308
  
  Pfam
  PF00628 (PHD)
  
  2,316 - 2,364
  
  Pfam
  PF00628 (PHD)
  
  347 - 390
  
  Pfam
  PF00628 (PHD)
IPR001487

Bromodomain
1. SSF47370 (Bromodomain)
  
  2,379 - 2,483
  
  SUPERFAMILY
  SSF47370 (Bromodomain)
2. SM00297 (bromo_6)
  
  2,373 - 2,481
  
  SMART
  SM00297 (bromo_6)
3. PS50014 (BROMODOMAIN_2)
  
  2,392 - 2,462
  
  PROSITE profiles
  PS50014 (BROMODOMAIN_2)
4. PF00439 (Bromodomain)
  
  2,385 - 2,466
  
  Pfam
  PF00439 (Bromodomain)
5. PR00503 (BROMODOMAIN)
  
  2,443 - 2,462
  
  PRINTS
  PR00503 (BROMODOMAIN)
  
  2,409 - 2,425
  
  PRINTS
  PR00503 (BROMODOMAIN)
  
  2,395 - 2,408
  
  PRINTS
  PR00503 (BROMODOMAIN)
  
  2,425 - 2,443
  
  PRINTS
  PR00503 (BROMODOMAIN)
6. G3DSA:1.20.92...
  
  2,084 - 2,100
  
  GENE3D
  G3DSA:1.20.920.10 (G3DSA:1.20.920.10)
  
  2,380 - 2,486
  
  GENE3D
  G3DSA:1.20.920.10 (G3DSA:1.20.920.10)
IPR019786

Zinc finger, PHD-type, conserved site
1. PS01359 (ZF_PHD_1)
  
  347 - 388
  
  PROSITE patterns
  PS01359 (ZF_PHD_1)
  
  2,303 - 2,362
  
  PROSITE patterns
  PS01359 (ZF_PHD_1)
  
  2,261 - 2,335
  
  PROSITE patterns
  PS01359 (ZF_PHD_1)
IPR018359

Bromodomain, conserved site
1. PS00633 (BROMODOMAIN_1)
  
  2,397 - 2,454
  
  PROSITE patterns
  PS00633 (BROMODOMAIN_1)

no IPR

Unintegrated signatures

Coil

929 - 949

COILS
Coil (Coil)

1,506 - 1,533

COILS
Coil (Coil)

750 - 771

COILS
Coil (Coil)
cd05509 (Bromo_gcn5...)

2,379 - 2,477

CDD
cd05509 (Bromo_gcn5_like)
cd15559 (PHD1_BPTF)

346 - 388

CDD
cd15559 (PHD1_BPTF)
cd15560 (PHD2_3_BPTF)

2,261 - 2,306

CDD
cd15560 (PHD2_3_BPTF)

2,316 - 2,362

CDD
cd15560 (PHD2_3_BPTF)
mobidb-lite (disord...)

505 - 569

MobiDB Lite
mobidb-lite (disorder_prediction)

1,666 - 1,705

MobiDB Lite
mobidb-lite (disorder_prediction)

1,479 - 1,552

MobiDB Lite
mobidb-lite (disorder_prediction)

1,958 - 1,984

MobiDB Lite
mobidb-lite (disorder_prediction)

2,227 - 2,251

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 178

MobiDB Lite
mobidb-lite (disorder_prediction)

1,593 - 1,616

MobiDB Lite
mobidb-lite (disorder_prediction)

1,441 - 1,465

MobiDB Lite
mobidb-lite (disorder_prediction)

2,072 - 2,139

MobiDB Lite
mobidb-lite (disorder_prediction)

1,167 - 1,211

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative histone H...

346H

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

355D

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

356L

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

357L

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

358C

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

359C

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

363P

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)

383W

putative histone H3 binding site
346H, 355D, 356L, 357L, 358C, 359C, 363P, 383W
CDD
cd15559 (PHD1_BPTF)
Zn binding site cd...

347C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

350C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

359C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

362C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

367H

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

370C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

385C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)

388C

Zn binding site
347C, 350C, 359C, 362C, 367H, 370C, 385C, 388C
CDD
cd15559 (PHD1_BPTF)
Zn binding site cd...

2,261C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,263C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,276C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,279C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,284H

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,287C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,303C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)

2,306C

Zn binding site
2,261C, 2,263C, 2,276C, 2,279C, 2,284H, 2,287C, 2,303C, 2,306C
CDD
cd15560 (PHD2_3_BPTF)
histone H3 binding...

2,267Y

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,269N

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,272F

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,273Y

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,274V

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,275G

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,276C

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,277E

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,280S

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,282W

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,292E

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,295S

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,298M

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)

2,299E

histone H3 binding site
2,267Y, 2,269N, 2,272F, 2,273Y, 2,274V, 2,275G, 2,276C, 2,277E, 2,280S, 2,282W, 2,292E, 2,295S, 2,298M, 2,299E
CDD
cd15560 (PHD2_3_BPTF)
histone H3 binding...

2,316Y

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,323Y

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,325N

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,328F

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,329Y

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,330I

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,331C

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,332C

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,333D

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,336Q

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,338W

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,348Q

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,351A

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,354I

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)

2,355D

histone H3 binding site
2,316Y, 2,323Y, 2,325N, 2,328F, 2,329Y, 2,330I, 2,331C, 2,332C, 2,333D, 2,336Q, 2,338W, 2,348Q, 2,351A, 2,354I, 2,355D
CDD
cd15560 (PHD2_3_BPTF)
Zn binding site cd...

2,317C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,319C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,332C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,335C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,340H

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,343C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,359C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)

2,362C

Zn binding site
2,317C, 2,319C, 2,332C, 2,335C, 2,340H, 2,343C, 2,359C, 2,362C
CDD
cd15560 (PHD2_3_BPTF)
acetyllysine bindi...

2,404V

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

2,409A

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

2,412Y

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

2,451C

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

2,455N

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

2,461F

acetyllysine binding site
2,404V, 2,409A, 2,412Y, 2,451C, 2,455N, 2,461F
CDD
cd05509 (Bromo_gcn5_like)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO05720

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component