KWMTBOMO05535

Protein

Length

520 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
32 - 506
Aldehyde/histidinol dehydrogenase (IPR016161)
Aldehyde dehydrogenase domain (IPR015590)
Domain
32 - 286
Aldehyde dehydrogenase N-terminal domain (IPR016162)
287 - 467
Aldehyde dehydrogenase, C-terminal (IPR016163)

1 50 100 150 200 250 300 350 400 450 520

Detailed signature matches

IPR016162

Aldehyde dehydrogenase N-terminal domain
1. G3DSA:3.40.60...
  
  32 - 286
  
  GENE3D
  G3DSA:3.40.605.10 (G3DSA:3.40.605.10)
IPR016161

Aldehyde/histidinol dehydrogenase
1. SSF53720 (ALDH-like)
  
  32 - 506
  
  SUPERFAMILY
  SSF53720 (ALDH-like)
IPR015590

Aldehyde dehydrogenase domain
1. PF00171 (Aldedh)
  
  39 - 500
  
  Pfam
  PF00171 (Aldedh)
IPR016163

Aldehyde dehydrogenase, C-terminal
1. G3DSA:3.40.30...
  
  287 - 467
  
  GENE3D
  G3DSA:3.40.309.10 (G3DSA:3.40.309.10)
IPR029510

Aldehyde dehydrogenase, glutamic acid active site
1. PS00687 (ALDEHYDE_D...)
  
  272 - 279
  
  PROSITE patterns
  PS00687 (ALDEHYDE_DEHYDR_GLU)

no IPR

Unintegrated signatures

cd07130 (ALDH_F7_AA...)

30 - 506

CDD
cd07130 (ALDH_F7_AASADH)

Residue annotation

tetrameric interfa...

77H

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

83P

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

86A

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

92R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

99R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

138S

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

139R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

141L

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

143G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

145V

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

147P

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

148S

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

149E

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

150R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

157E

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

158K

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

160N

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

257Q

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

260G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

261V

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

264Q

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

269R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

270H

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

297F

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

333G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

347L

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

421E

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

444G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

450I

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

451G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

455S

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

458G

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

460V

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

461N

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

462V

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

463N

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

469A

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

470E

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

474A

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

478E

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

485R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

489S

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

490D

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

493K

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

497R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

498R

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

499A

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

500T

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

501V

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

502T

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

504N

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)

505Y

tetrameric interface
77H, 83P, 86A, 92R, 99R, 138S, 139R, 141L, 143G, 145V, 147P, 148S, 149E, 150R, 157E, 158K, 160N, 257Q, 260G, 261V, 264Q, 269R, 270H, 297F, 333G, 347L, 421E, 444G, 450I, 451G, 455S, 458G, 460V, 461N, 462V, 463N, 469A, 470E, 474A, 478E, 485R, 489S, 490D, 493K, 497R, 498R, 499A, 500T, 501V, 502T, 504N, 505Y
CDD
cd07130 (ALDH_F7_AASADH)
NAD binding site c...

169T

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

170A

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

171F

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

172N

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

195K

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

197S

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

198E

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

235G

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

236E

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

249F

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

250T

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

251G

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

252S

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

255V

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

258Q

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

273E

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

274L

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

275G

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

307C

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

406E

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)

475F

NAD binding site
169T, 170A, 171F, 172N, 195K, 197S, 198E, 235G, 236E, 249F, 250T, 251G, 252S, 255V, 258Q, 273E, 274L, 275G, 307C, 406E, 475F
CDD
cd07130 (ALDH_F7_AASADH)
catalytic residues...

172N

catalytic residues
172N, 273E, 304G, 307C
CDD
cd07130 (ALDH_F7_AASADH)

273E

catalytic residues
172N, 273E, 304G, 307C
CDD
cd07130 (ALDH_F7_AASADH)

304G

catalytic residues
172N, 273E, 304G, 307C
CDD
cd07130 (ALDH_F7_AASADH)

307C

catalytic residues
172N, 273E, 304G, 307C
CDD
cd07130 (ALDH_F7_AASADH)

GO term prediction

Biological Process

GO:0008152 metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

Cellular Component