KWMTBOMO05465

Protein

Length

1,437 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
745 - 779
WW domain (IPR001202)
1,073 - 1,437
HECT domain (IPR000569)

1 200 400 600 800 1000 1200 1437

Detailed signature matches

IPR001202

WW domain
1. PS01159 (WW_DOMAIN_1)
  
  752 - 777
  
  PROSITE patterns
  PS01159 (WW_DOMAIN_1)
2. SSF51045 (WW domain)
  
  745 - 778
  
  SUPERFAMILY
  SSF51045 (WW domain)
3. PS50020 (WW_DOMAIN_2)
  
  746 - 779
  
  PROSITE profiles
  PS50020 (WW_DOMAIN_2)
4. PF00397 (WW)
  
  748 - 777
  
  Pfam
  PF00397 (WW)
5. SM00456 (ww_5)
  
  747 - 779
  
  SMART
  SM00456 (ww_5)
IPR000569

HECT domain
1. SSF56204 (Hect, E3 ...)
  
  1,073 - 1,431
  
  SUPERFAMILY
  SSF56204 (Hect, E3 ligase catalytic domain)
2. cd00078 (HECTc)
  
  1,080 - 1,435
  
  CDD
  cd00078 (HECTc)
3. SM00119 (hect_3)
  
  1,099 - 1,437
  
  SMART
  SM00119 (hect_3)
4. PS50237 (HECT)
  
  1,101 - 1,437
  
  PROSITE profiles
  PS50237 (HECT)
5. PF00632 (HECT)
  
  1,132 - 1,436
  
  Pfam
  PF00632 (HECT)

no IPR

Unintegrated signatures

G3DSA:2.20.70.10

745 - 777

GENE3D
G3DSA:2.20.70.10 (G3DSA:2.20.70.10)
G3DSA:3.30.21...

1,205 - 1,280

GENE3D
G3DSA:3.30.2160.10 (G3DSA:3.30.2160.10)
cd00201 (WW)

749 - 777

CDD
cd00201 (WW)
mobidb-lite (disord...)

808 - 843

MobiDB Lite
mobidb-lite (disorder_prediction)

608 - 643

MobiDB Lite
mobidb-lite (disorder_prediction)

549 - 594

MobiDB Lite
mobidb-lite (disorder_prediction)

245 - 264

MobiDB Lite
mobidb-lite (disorder_prediction)

774 - 795

MobiDB Lite
mobidb-lite (disorder_prediction)

155 - 213

MobiDB Lite
mobidb-lite (disorder_prediction)

501 - 532

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

binding pocket cd0...

763F

binding pocket
763F, 774W
CDD
cd00201 (WW)

774W

binding pocket
763F, 774W
CDD
cd00201 (WW)
catalytic cleft cd...

1,086R

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,117E

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,128E

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,189E

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,364F

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,399L

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,400P

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,403H

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,404T

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,405C

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,406F

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,407N

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,427A

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)

1,434F

catalytic cleft
1,086R, 1,117E, 1,128E, 1,189E, 1,364F, 1,399L, 1,400P, 1,403H, 1,404T, 1,405C, 1,406F, 1,407N, 1,427A, 1,434F
CDD
cd00078 (HECTc)
E2 interaction sit...

1,217F

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,220S

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,221L

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,223W

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,224L

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,233L

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,235L

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,239V

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,240S

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,242R

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,248V

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,253L

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,270Y

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

1,274V

E2 interaction site
1,217F, 1,220S, 1,221L, 1,223W, 1,224L, 1,233L, 1,235L, 1,239V, 1,240S, 1,242R, 1,248V, 1,253L, 1,270Y, 1,274V
CDD
cd00078 (HECTc)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO05465

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component