KWMTBOMO05325

Protein

Length

1,530 amino acids

Protein family membership

Protein of unknown function DUF1759 (IPR005312)

Retrotransposon, Pao (IPR008042)

Domains and repeats

Domain
647 - 730
Peptidase A2A, retrovirus, catalytic (IPR001995)
Domain
647 - 796
Peptidase aspartic, putative (IPR008737)

1 200 400 600 800 1000 1200 1400 1530

Detailed signature matches

IPR005312

Protein of unknown function DUF1759
1. PF03564 (DUF1759)
  
  295 - 431
  
  Pfam
  PF03564 (DUF1759)
IPR008042

Retrotransposon, Pao
1. PF05380 (Peptidase_A17)
  
  1,172 - 1,335
  
  Pfam
  PF05380 (Peptidase_A17)
IPR001995

Peptidase A2A, retrovirus, catalytic
1. PS50175 (ASP_PROT_R...)
  
  647 - 730
  
  PROSITE profiles
  PS50175 (ASP_PROT_RETROV)
IPR008737

Peptidase aspartic, putative
1. PF05585 (DUF1758)
  
  647 - 796
  
  Pfam
  PF05585 (DUF1758)

no IPR

Unintegrated signatures

Coil

112 - 139

COILS
Coil (Coil)
SSF56672 (DNA/RNA p...)

897 - 1,113

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)

1,150 - 1,342

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd00303 (retropepsi...)

638 - 709

CDD
cd00303 (retropepsin_like)
cd01644 (RT_pepA17)

938 - 1,155

CDD
cd01644 (RT_pepA17)
mobidb-lite (disord...)

1,458 - 1,530

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Catalytic residue ...

652D

Catalytic residue
652D
CDD
cd00303 (retropepsin_like)
catalytic motif cd...

652D

catalytic motif
652D, 653D, 654G
CDD
cd00303 (retropepsin_like)

653D

catalytic motif
652D, 653D, 654G
CDD
cd00303 (retropepsin_like)

654G

catalytic motif
652D, 653D, 654G
CDD
cd00303 (retropepsin_like)
inhibitor binding ...

652D

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)

654G

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)

656T

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)

679V

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)

680N

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)

681G

inhibitor binding site
652D, 654G, 656T, 679V, 680N, 681G
CDD
cd00303 (retropepsin_like)
Active site flap c...

679V

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

680N

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

681G

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

682I

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

685L

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

686S

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)

687R

Active site flap
679V, 680N, 681G, 682I, 685L, 686S, 687R
CDD
cd00303 (retropepsin_like)
putative NTP bindi...

998D

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

999I

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,000R

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,001E

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,002M

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,003F

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,038F

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)

1,076D

putative NTP binding site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,076D
CDD
cd01644 (RT_pepA17)
putative active si...

998D

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

999I

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,000R

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,001E

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,002M

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,003F

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,038F

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,039G

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,074Y

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,076D

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,077D

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,146L

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)

1,147G

putative active site
998D, 999I, 1,000R, 1,001E, 1,002M, 1,003F, 1,038F, 1,039G, 1,074Y, 1,076D, 1,077D, 1,146L, 1,147G
CDD
cd01644 (RT_pepA17)
putative nucleic a...

1,039G

putative nucleic acid binding site
1,039G
CDD
cd01644 (RT_pepA17)

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004190 aspartic-type endopeptidase activity

Cellular Component

None predicted.

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Entry type

Status

Per-residue features

KWMTBOMO05325

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component