KWMTBOMO05236

Protein

Length

408 amino acids

Protein family membership

Major facilitator superfamily (IPR011701)
- Tetracycline resistance protein TetA/multidrug resistance protein MdtG (IPR001958)

Domains and repeats

Domain
2 - 402
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 408

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  9 - 278
  
  Pfam
  PF07690 (MFS_1)
IPR001958

Tetracycline resistance protein TetA/multidrug resistance protein MdtG
1. PR01035 (TCRTETA)
  
  348 - 371
  
  PRINTS
  PR01035 (TCRTETA)
  
  127 - 149
  
  PRINTS
  PR01035 (TCRTETA)
  
  12 - 28
  
  PRINTS
  PR01035 (TCRTETA)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  2 - 402
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  9 - 394
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  6 - 398
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

9 - 180

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

217 - 394

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

17A

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

20L

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

21M

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

22P

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

24L

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

25A

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

42S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

45Y

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

46S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

49Q

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

53G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

54P

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

56V

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

57G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

103K

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

104Q

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

106Q

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

107L

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

110N

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

111A

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

114P

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

127Y

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

128G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

131S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

132T

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

138M

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

231T

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

234V

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

235G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

238F

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

239S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

242S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

256L

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

260I

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

264G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

267G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

271T

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

322A

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

325G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

326S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

329R

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

333L

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

334E

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

337A

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

348I

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

349I

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

352S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

353N

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

356K

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

357S

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

360G

putative substrate translocation pore
17A, 20L, 21M, 22P, 24L, 25A, 42S, 45Y, 46S, 49Q, 53G, 54P, 56V, 57G, 103K, 104Q, 106Q, 107L, 110N, 111A, 114P, 127Y, 128G, 131S, 132T, 138M, 231T, 234V, 235G, 238F, 239S, 242S, 256L, 260I, 264G, 267G, 271T, 322A, 325G, 326S, 329R, 333L, 334E, 337A, 348I, 349I, 352S, 353N, 356K, 357S, 360G
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features

KWMTBOMO05236

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component