KWMTBOMO04944

Protein

Length

501 amino acids

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)

Domains and repeats

Domain
42 - 497
Major facilitator superfamily domain (IPR020846)

1 50 100 150 200 250 300 350 400 450 501

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  121 - 496
  
  Pfam
  PF00083 (Sugar_tr)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  42 - 492
  
  PROSITE profiles
  PS50850 (MFS)
2. cd06174 (MFS)
  
  116 - 488
  
  CDD
  cd06174 (MFS)
3. SSF103473 (MFS gene...)
  
  117 - 497
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)

no IPR

Unintegrated signatures

G3DSA:1.20.12...

117 - 260

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

315 - 495

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

Residue annotation

putative substrate...

123Q

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

126L

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

127M

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

130V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

134V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

135S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

137F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

138C

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

184S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

185G

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

188L

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

189G

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

192S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

193I

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

196A

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

208V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

209S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

212L

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

213V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

219Q

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

334G

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

337F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

338F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

341N

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

342E

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

345S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

353I

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

357V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

361G

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

364V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

368V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

416V

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

419S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

420C

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

423F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

427F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

428T

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

431T

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

442G

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

443F

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

446S

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

447A

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

450T

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

451K

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

454A

putative substrate translocation pore
123Q, 126L, 127M, 130V, 134V, 135S, 137F, 138C, 184S, 185G, 188L, 189G, 192S, 193I, 196A, 208V, 209S, 212L, 213V, 219Q, 334G, 337F, 338F, 341N, 342E, 345S, 353I, 357V, 361G, 364V, 368V, 416V, 419S, 420C, 423F, 427F, 428T, 431T, 442G, 443F, 446S, 447A, 450T, 451K, 454A
CDD
cd06174 (MFS)

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features