KWMTBOMO04863

Protein

Length

3,376 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
553 - 753
Endonuclease/exonuclease/phosphatase (IPR005135)
1,035 - 1,311
Reverse transcriptase domain (IPR000477)
2,288 - 2,333
Zinc finger, CCHC-type (IPR001878)
2,403 - 2,596
Endonuclease/exonuclease/phosphatase (IPR005135)
2,884 - 3,007
Reverse transcriptase domain (IPR000477)

1 500 1000 1500 2000 2500 3000 3376

Detailed signature matches

IPR005135

Endonuclease/exonuclease/phosphatase
1. G3DSA:3.60.10.10
  
  553 - 753
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
  
  2,404 - 2,596
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
2. PF14529 (Exo_endo_p...)
  
  2,473 - 2,591
  
  Pfam
  PF14529 (Exo_endo_phos_2)
  
  630 - 748
  
  Pfam
  PF14529 (Exo_endo_phos_2)
3. SSF56219 (DNase I-like)
  
  553 - 753
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
  
  2,403 - 2,596
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  2,884 - 3,007
  
  Pfam
  PF00078 (RVT_1)
  
  1,058 - 1,311
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,035 - 1,292
  
  PROSITE profiles
  PS50878 (RT_POL)
IPR001878

Zinc finger, CCHC-type
1. PS50158 (ZF_CCHC)
  
  2,318 - 2,331
  
  PROSITE profiles
  PS50158 (ZF_CCHC)
2. G3DSA:4.10.60.10
  
  2,288 - 2,333
  
  GENE3D
  G3DSA:4.10.60.10 (G3DSA:4.10.60.10)
3. PF00098 (zf-CCHC)
  
  2,317 - 2,332
  
  Pfam
  PF00098 (zf-CCHC)
4. SM00343 (c2hcfinal6)
  
  2,294 - 2,310
  
  SMART
  SM00343 (c2hcfinal6)
  
  2,317 - 2,333
  
  SMART
  SM00343 (c2hcfinal6)
5. SSF57756 (Retroviru...)
  
  2,290 - 2,333
  
  SUPERFAMILY
  SSF57756 (Retrovirus zinc finger-like domains)

no IPR

Unintegrated signatures

Coil

219 - 239

COILS
Coil (Coil)

1,864 - 1,884

COILS
Coil (Coil)

2,692 - 2,712

COILS
Coil (Coil)

1,824 - 1,844

COILS
Coil (Coil)

312 - 332

COILS
Coil (Coil)

266 - 286

COILS
Coil (Coil)

1,917 - 1,937

COILS
Coil (Coil)
SSF56672 (DNA/RNA p...)

992 - 1,298

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01650 (RT_nLTR_like)

1,048 - 1,311

CDD
cd01650 (RT_nLTR_like)
cd09077 (R1-I-EN)

553 - 751

CDD
cd09077 (R1-I-EN)

2,399 - 2,594

CDD
cd09077 (R1-I-EN)
mobidb-lite (disord...)

2,071 - 2,113

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 56

MobiDB Lite
mobidb-lite (disorder_prediction)

442 - 485

MobiDB Lite
mobidb-lite (disorder_prediction)

326 - 430

MobiDB Lite
mobidb-lite (disorder_prediction)

2,799 - 2,833

MobiDB Lite
mobidb-lite (disorder_prediction)

1,553 - 1,656

MobiDB Lite
mobidb-lite (disorder_prediction)

956 - 989

MobiDB Lite
mobidb-lite (disorder_prediction)

1,738 - 1,757

MobiDB Lite
mobidb-lite (disorder_prediction)

1,676 - 1,730

MobiDB Lite
mobidb-lite (disorder_prediction)

73 - 126

MobiDB Lite
mobidb-lite (disorder_prediction)

1,929 - 2,059

MobiDB Lite
mobidb-lite (disorder_prediction)

2,350 - 2,401

MobiDB Lite
mobidb-lite (disorder_prediction)

3,001 - 3,068

MobiDB Lite
mobidb-lite (disorder_prediction)

3,342 - 3,376

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

phosphate binding ...

554N

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)

579E

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)

634Y

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)

668D

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)

670N

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)

745H

phosphate binding site
554N, 579E, 634Y, 668D, 670N, 745H
CDD
cd09077 (R1-I-EN)
putative metal bin...

579E

putative metal binding site
579E, 744D
CDD
cd09077 (R1-I-EN)

744D

putative metal binding site
579E, 744D
CDD
cd09077 (R1-I-EN)
putative catalytic...

579E

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

634Y

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

668D

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

670N

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

718D

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

744D

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)

745H

putative catalytic site
579E, 634Y, 668D, 670N, 718D, 744D, 745H
CDD
cd09077 (R1-I-EN)
putative NTP bindi...

1,139D

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,140V

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,141R

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,142N

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,143A

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,144F

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,198Q

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)

1,233D

putative NTP binding site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,233D
CDD
cd01650 (RT_nLTR_like)
putative active si...

1,139D

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,140V

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,141R

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,142N

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,143A

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,144F

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,198Q

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,199G

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,231Y

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,233D

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,234D

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,309L

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)

1,310G

putative active site
1,139D, 1,140V, 1,141R, 1,142N, 1,143A, 1,144F, 1,198Q, 1,199G, 1,231Y, 1,233D, 1,234D, 1,309L, 1,310G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

1,199G

putative nucleic acid binding site
1,199G
CDD
cd01650 (RT_nLTR_like)
putative metal bin...

2,422E

putative metal binding site
2,422E, 2,587D
CDD
cd09077 (R1-I-EN)

2,587D

putative metal binding site
2,422E, 2,587D
CDD
cd09077 (R1-I-EN)
putative catalytic...

2,422E

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,477Y

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,511D

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,513N

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,561D

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,587D

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)

2,588H

putative catalytic site
2,422E, 2,477Y, 2,511D, 2,513N, 2,561D, 2,587D, 2,588H
CDD
cd09077 (R1-I-EN)
phosphate binding ...

2,422E

phosphate binding site
2,422E, 2,477Y, 2,511D, 2,513N, 2,588H
CDD
cd09077 (R1-I-EN)

2,477Y

phosphate binding site
2,422E, 2,477Y, 2,511D, 2,513N, 2,588H
CDD
cd09077 (R1-I-EN)

2,511D

phosphate binding site
2,422E, 2,477Y, 2,511D, 2,513N, 2,588H
CDD
cd09077 (R1-I-EN)

2,513N

phosphate binding site
2,422E, 2,477Y, 2,511D, 2,513N, 2,588H
CDD
cd09077 (R1-I-EN)

2,588H

phosphate binding site
2,422E, 2,477Y, 2,511D, 2,513N, 2,588H
CDD
cd09077 (R1-I-EN)

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO04863

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component