KWMTBOMO04635

Protein

Length

354 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
21 - 162
GroES-like (IPR011032)
178 - 308
Alcohol dehydrogenase, C-terminal (IPR013149)
314 - 352
GroES-like (IPR011032)
Domain
144 - 321
NAD(P)-binding domain (IPR016040)

1 50 100 150 200 250 300 354

Detailed signature matches

IPR011032

GroES-like
1. G3DSA:3.90.18...
  
  21 - 160
  
  GENE3D
  G3DSA:3.90.180.10 (G3DSA:3.90.180.10)
2. SSF50129 (GroES-like)
  
  314 - 352
  
  SUPERFAMILY
  SSF50129 (GroES-like)
  
  21 - 162
  
  SUPERFAMILY
  SSF50129 (GroES-like)
IPR016040

NAD(P)-binding domain
1. SSF51735 (NAD(P)-bi...)
  
  144 - 316
  
  SUPERFAMILY
  SSF51735 (NAD(P)-binding Rossmann-fold domains)
2. G3DSA:3.40.50...
  
  161 - 321
  
  GENE3D
  G3DSA:3.40.50.720 (G3DSA:3.40.50.720)
IPR013149

Alcohol dehydrogenase, C-terminal
1. PF00107 (ADH_zinc_N)
  
  178 - 308
  
  Pfam
  PF00107 (ADH_zinc_N)

no IPR

Unintegrated signatures

PF16884 (ADH_N_2)

24 - 121

Pfam
PF16884 (ADH_N_2)
cd08294 (leukotrien...)

20 - 353

CDD
cd08294 (leukotriene_B4_DH_like)

Residue annotation

dimer interface cd...

32Q

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

35P

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

36K

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

37K

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

70A

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

73I

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

74G

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

258Y

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

263V

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

264C

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

265G

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

266S

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

269S

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

285I

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

286V

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

289E

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

290L

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

291K

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

292I

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

293E

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

294G

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

295F

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

296L

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)

299R

dimer interface
32Q, 35P, 36K, 37K, 70A, 73I, 74G, 258Y, 263V, 264C, 265G, 266S, 269S, 285I, 286V, 289E, 290L, 291K, 292I, 293E, 294G, 295F, 296L, 299R
CDD
cd08294 (leukotriene_B4_DH_like)
NAD(P) binding sit...

66P

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

149M

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

153T

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

174G

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

177G

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

178A

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

179V

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

198A

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

199G

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

203K

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

219Y

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

242N

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

243V

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

264C

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

265G

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

266S

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

267I

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

268S

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

270Y

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

295F

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

296L

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

297V

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

340M

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

341L

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

343G

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)

345N

NAD(P) binding site
66P, 149M, 153T, 174G, 177G, 178A, 179V, 198A, 199G, 203K, 219Y, 242N, 243V, 264C, 265G, 266S, 267I, 268S, 270Y, 295F, 296L, 297V, 340M, 341L, 343G, 345N
CDD
cd08294 (leukotriene_B4_DH_like)
substrate binding ...

67F

substrate binding site
67F, 70A, 264C, 270Y, 298D
CDD
cd08294 (leukotriene_B4_DH_like)

70A

substrate binding site
67F, 70A, 264C, 270Y, 298D
CDD
cd08294 (leukotriene_B4_DH_like)

264C

substrate binding site
67F, 70A, 264C, 270Y, 298D
CDD
cd08294 (leukotriene_B4_DH_like)

270Y

substrate binding site
67F, 70A, 264C, 270Y, 298D
CDD
cd08294 (leukotriene_B4_DH_like)

298D

substrate binding site
67F, 70A, 264C, 270Y, 298D
CDD
cd08294 (leukotriene_B4_DH_like)

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

KWMTBOMO04635

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

GO term prediction

Biological Process

Molecular Function

Cellular Component