Protein

KWMTBOMO04613

Length
1,259 amino acids

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1259

Detailed signature matches

  1. Domain IPR015123
    Bcr-Abl oncoprotein oligomerisation
    1. PF09036 (Bcr-Abl_Oligo)
    2. G3DSA:4.10.28...
  2. Domain IPR000219
    Dbl homology (DH) domain
    1. SSF48065 (DBL homol...)
    2. PS50010 (DH_2)
    3. SM00325 (RhoGEF_3)
    4. PF00621 (RhoGEF)
    5. G3DSA:1.20.90...
  3. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  4. Domain IPR001849
    Pleckstrin homology domain
    1. PS50003 (PH_DOMAIN)
    2. SM00233 (PH_update)
  5. Domain IPR000008
    C2 domain
    1. G3DSA:2.60.40...
    2. SSF49562 (C2 domain...)
    3. PF00168 (C2)
  6. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  7. Domain IPR000198
    Rho GTPase-activating protein domain
    1. G3DSA:1.10.55...
    2. SM00324 (RhoGAP_3)
    3. PF00620 (RhoGAP)
    4. PS50238 (RHOGAP)
  8. SITE IPR001331
    Guanine-nucleotide dissociation stimulator, CDC24, conserved site
    1. PS00741 (DH_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. cd00160 (RhoGEF)
  3. cd13368 (PH_BCR_art...)
  4. mobidb-lite (disord...)

Residue annotation

  1. GTPase interaction...

GO term prediction

Biological Process

GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

GO:0004674 protein serine/threonine kinase activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding

Cellular Component

None predicted.