KWMTBOMO04474

Protein

Length

528 amino acids

Protein family membership

None predicted.

Domains and repeats

Domain
10 - 172
SMAD/FHA domain (IPR008984)
Forkhead-associated (FHA) domain (IPR000253)
Domain
161 - 455
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 50 100 150 200 250 300 350 400 450 500 528

Detailed signature matches

IPR008984

SMAD/FHA domain
1. SSF49879 (SMAD/FHA ...)
  
  10 - 172
  
  SUPERFAMILY
  SSF49879 (SMAD/FHA domain)
IPR000253

Forkhead-associated (FHA) domain
1. SM00240 (FHA_2)
  
  67 - 128
  
  SMART
  SM00240 (FHA_2)
2. PF00498 (FHA)
  
  69 - 143
  
  Pfam
  PF00498 (FHA)
3. PS50006 (FHA_DOMAIN)
  
  68 - 128
  
  PROSITE profiles
  PS50006 (FHA_DOMAIN)
4. G3DSA:2.60.20...
  
  36 - 160
  
  GENE3D
  G3DSA:2.60.200.20 (G3DSA:2.60.200.20)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  161 - 455
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. SM00220 (serkin_6)
  
  173 - 440
  
  SMART
  SM00220 (serkin_6)
2. PS50011 (PROTEIN_KI...)
  
  173 - 440
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
3. PF00069 (Pkinase)
  
  175 - 440
  
  Pfam
  PF00069 (Pkinase)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  297 - 309
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

287 - 443

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

161 - 286

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd00060 (FHA)

93 - 142

CDD
cd00060 (FHA)
cd14084 (STKc_Chk2)

166 - 440

CDD
cd14084 (STKc_Chk2)
mobidb-lite (disord...)

1 - 28

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

phosphopeptide bin...

94S

phosphopeptide binding site
94S, 95K, 118H, 119N, 120G
CDD
cd00060 (FHA)

95K

phosphopeptide binding site
94S, 95K, 118H, 119N, 120G
CDD
cd00060 (FHA)

118H

phosphopeptide binding site
94S, 95K, 118H, 119N, 120G
CDD
cd00060 (FHA)

119N

phosphopeptide binding site
94S, 95K, 118H, 119N, 120G
CDD
cd00060 (FHA)

120G

phosphopeptide binding site
94S, 95K, 118H, 119N, 120G
CDD
cd00060 (FHA)
dimer interface cd...

174Y

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

175I

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

177R

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

179L

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

181Q

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

189L

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

191Y

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

196C

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

198K

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

207S

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

210T

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

211N

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

212G

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

222K

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

257L

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

264F

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

268T

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

269K

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

344Y

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

379L

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)

382S

dimer interface
174Y, 175I, 177R, 179L, 181Q, 189L, 191Y, 196C, 198K, 207S, 210T, 211N, 212G, 222K, 257L, 264F, 268T, 269K, 344Y, 379L, 382S
CDD
cd14084 (STKc_Chk2)
ATP binding site c...

179L

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

180G

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

181Q

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

182G

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

183A

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

184C

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

185G

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

187V

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

200A

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

202K

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

239I

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

255L

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

256E

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

257L

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

258M

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

262E

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

305E

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

306N

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

308L

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)

322D

ATP binding site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 305E, 306N, 308L, 322D
CDD
cd14084 (STKc_Chk2)
active site cd14084

179L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

180G

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

181Q

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

182G

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

183A

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

184C

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

185G

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

187V

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

200A

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

202K

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

239I

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

255L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

256E

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

257L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

258M

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

262E

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

264F

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

300R

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

301D

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

303K

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

305E

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

306N

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

308L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

321T

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

322D

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

325L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

339C

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

340G

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

341T

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

342P

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

343L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

345L

active site
179L, 180G, 181Q, 182G, 183A, 184C, 185G, 187V, 200A, 202K, 239I, 255L, 256E, 257L, 258M, 262E, 264F, 300R, 301D, 303K, 305E, 306N, 308L, 321T, 322D, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)
polypeptide substr...

183A

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

262E

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

264F

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

300R

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

301D

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

303K

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

305E

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

325L

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

339C

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

340G

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

341T

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

342P

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

343L

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)

345L

polypeptide substrate binding site
183A, 262E, 264F, 300R, 301D, 303K, 305E, 325L, 339C, 340G, 341T, 342P, 343L, 345L
CDD
cd14084 (STKc_Chk2)
activation loop (A...

321T

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

322D

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

323F

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

324G

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

325L

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

326S

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

327K

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

328F

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

329V

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

330G

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

331E

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

335M

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

336K

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

337T

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

338M

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

339C

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

340G

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

341T

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

342P

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

343L

activation loop (A-loop)
321T, 322D, 323F, 324G, 325L, 326S, 327K, 328F, 329V, 330G, 331E, 335M, 336K, 337T, 338M, 339C, 340G, 341T, 342P, 343L
CDD
cd14084 (STKc_Chk2)

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component