KWMTBOMO04469

Protein

Length

259 amino acids

Protein family membership

Replication factor A protein 2 (IPR014646)

Domains and repeats

Domain
38 - 153
Nucleic acid-binding, OB-fold (IPR012340)
OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (IPR004365)
190 - 258
Winged helix-turn-helix DNA-binding domain (IPR011991)
Domain
164 - 251
Replication protein A, C-terminal (IPR014892)

1 50 100 150 200 259

Detailed signature matches

IPR014646

Replication factor A protein 2
1. PIRSF036949 (RPA32)
  
  3 - 257
  
  PIRSF
  PIRSF036949 (RPA32)
IPR012340

Nucleic acid-binding, OB-fold
1. SSF50249 (Nucleic a...)
  
  38 - 153
  
  SUPERFAMILY
  SSF50249 (Nucleic acid-binding proteins)
IPR004365

OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
1. PF01336 (tRNA_anti-...)
  
  60 - 132
  
  Pfam
  PF01336 (tRNA_anti-codon)
IPR014892

Replication protein A, C-terminal
1. PF08784 (RPA_C)
  
  164 - 251
  
  Pfam
  PF08784 (RPA_C)
IPR011991

Winged helix-turn-helix DNA-binding domain
1. G3DSA:1.10.10.10
  
  191 - 258
  
  GENE3D
  G3DSA:1.10.10.10 (G3DSA:1.10.10.10)
2. SSF46785 ("Winged h...)
  
  190 - 257
  
  SUPERFAMILY
  SSF46785 ("Winged helix" DNA-binding domain)

no IPR

Unintegrated signatures

G3DSA:2.40.50...

30 - 158

GENE3D
G3DSA:2.40.50.140 (G3DSA:2.40.50.140)
cd04478 (RPA2_DBD_D)

59 - 152

CDD
cd04478 (RPA2_DBD_D)
mobidb-lite (disord...)

1 - 31

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

generic binding su...

66I

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

67R

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

68S

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

77T

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

78Y

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

79T

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

80I

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

82D

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

88R

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

89A

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

90V

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

92W

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

112D

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

119N

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

120V

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

121K

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

128V

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

129L

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)

130M

generic binding surface I
66I, 67R, 68S, 77T, 78Y, 79T, 80I, 82D, 88R, 89A, 90V, 92W, 112D, 119N, 120V, 121K, 128V, 129L, 130M
CDD
cd04478 (RPA2_DBD_D)
RPA2 DBD-D/RPA3 in...

67R

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

81Q

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

83I

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

113Y

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

139D

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

141N

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

143I

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

144T

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

147Y

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)

151I

RPA2 DBD-D/RPA3 interface
67R, 81Q, 83I, 113Y, 139D, 141N, 143I, 144T, 147Y, 151I
CDD
cd04478 (RPA2_DBD_D)
trimerization core...

67R

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

81Q

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

83I

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

113Y

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

132F

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

133K

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

135M

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

139D

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

141N

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

142I

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

143I

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

144T

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

145F

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

147Y

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

149Q

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

151I

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)

152H

trimerization core interface
67R, 81Q, 83I, 113Y, 132F, 133K, 135M, 139D, 141N, 142I, 143I, 144T, 145F, 147Y, 149Q, 151I, 152H
CDD
cd04478 (RPA2_DBD_D)
RPA2 DBD-D/RPA1 DB...

132F

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

133K

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

135M

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

142I

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

145F

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

149Q

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

152H

RPA2 DBD-D/RPA1 DBD-C interface
132F, 133K, 135M, 142I, 145F, 149Q, 152H
CDD
cd04478 (RPA2_DBD_D)

GO term prediction

Biological Process

GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination

Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding

Cellular Component

GO:0005634 nucleus

Filter view on

Entry type

Status

Per-residue features